Fiber-optic immunosensor based on lossy mode resonances induced by indium tin oxide thin-films
Fecha
2017Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Contribución a congreso / Biltzarrerako ekarpena
Versión
Versión aceptada / Onetsi den bertsioa
Impacto
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10.1109/ICSENS.2016.7808860
Resumen
A novel immunosensor based on lossy mode resonances (LMRs) induced in optical fibers is developed in this contribution. Indium tin oxide (ITO) is sputtered on the optical substrate to generate an LMR in the transmission spectrum. Type G immunoglobulins (IgGs) are then attached to the ITO-coated fiber using (3-glycidyloxypropyl)trimethoxysilane (GPTMS). A phosphate buffer saline solution containin ...
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A novel immunosensor based on lossy mode resonances (LMRs) induced in optical fibers is developed in this contribution. Indium tin oxide (ITO) is sputtered on the optical substrate to generate an LMR in the transmission spectrum. Type G immunoglobulins (IgGs) are then attached to the ITO-coated fiber using (3-glycidyloxypropyl)trimethoxysilane (GPTMS). A phosphate buffer saline solution containing anti-IgGs is used to detect the biological reactions. The presented device is capable of detecting anti-IgG concentrations up to 10 nM. These results will permit the fabrication of biosensors based on a covalent attachment of bioreceptors over an LMR inducing thin-film. [--]
Materias
Optical fiber,
Immunosensors,
Thin-films,
Lossy mode resonances,
Indium tin oxide
Editor
IEEE
Publicado en
En: IEEE. 2016 IEEE Sensors. 1 IEEE; 2017. p.1-3 978-1-4799-8287-5
Departamento
Universidad Pública de Navarra/Nafarroako Unibertsitate Publikoa. Institute of Smart Cities - ISC /
Universidad Pública de Navarra. Departamento de Ingeniería Eléctrica y Electrónica /
Nafarroako Unibertsitate Publikoa. Ingeniaritza Elektrikoa eta Elektronikoa Saila
Versión del editor
Entidades Financiadoras
This work was supported by a postdoctoral research grant of the Public
University of Navarre, by a Government of Navarre project “Development of
biosensors for Alzheimer’s disease” and by the Spanish Ministry of Economy
and Competitiveness project FEDER TEC2013-43679-R.