• Suicidal ideation and attempts among patients with lifetime physical and/or sexual abuse in treatment for substance use disorders 

  Fernández-Montalvo, Javier ; López-Goñi, José Javier ; Arteaga Olleta, Alfonso ; Haro Escribano, Begoña  (Taylor & Francis, 2019)   Artículo / Artikulua

  Background: Several studies indicate that lifetime abuse is a relevant risk factor for suicidal ideation and/or attempts. However, little is known about this phenomenon in patients seeking treatment for substance use ...

• International study of objectively-measured physical activity and sedentary time with body mass index and obesity: IPEN adult study 

  Dyck, Delfien Van; Cerin, Ester; Bourdeaudhuij, Ilse de; Hinckson, Erica A.; Reis, Rodrigo S.; Davey, Rachel; Sarmiento, Olga L.; Mitas, Josef; Troelsen, Jens; Aguinaga Ontoso, Inés  (Springer Nature, 2015)   Artículo / Artikulua  

  BACKGROUND: Physical activity (PA) has been consistently implicated in the etiology of obesity, whereas recent evidence on the importance of sedentary time remains inconsistent. Understanding of dose-response associations ...

• Transcriptional regulation of type 11 17β-hydroxysteroid dehydrogenase expression in prostate cancer cells 

  Rotinen Díaz, Mirja Sofia; Villar Bécares, Joaquín; Celay Leoz, Ion; Serrano Mendioroz, Irantzu; Notario, Vicente; Encío Martínez, Ignacio  (Elsevier, 2011)   Artículo / Artikulua  

  Type 11 Hydroxysteroid (17-beta) dehydrogenase (HSD17B11) catalyzes the conversion of 5α-androstan-3α,17β-diol into androsterone suggesting that it may play an important role in androgen metabolism. We previously described ...

• Perceived neighbourhood environmental attributes associated with adults’ recreational walking: IPEN Adult study in 12 countries 

  Sugiyama, Takemi; Cerin, Ester; Owen, Neville; Oyeyemi, Adewale L.; Conway, Terry L.; Dyck, Delfien Van; Schipperijn, Jasper; MacFarlane, Duncan; Salvo, Deborah; Orzanco Garralda, María Rosario  (Elsevier, 2014)   Artículo / Artikulua  

  This study examined the strength and shape of associations between perceived environmental attributes and adults’ recreational walking, using data collected from 13,745 adult participants in 12 countries. Perceived residential ...

• Moderating effects of age, gender and education on the associations of perceived neighborhood environment attributes with accelerometer-based physical activity: the IPEN Adult study 

  Dyck, Delfien Van; Cerin, Ester; Bourdeaudhuij, Ilse de; Salvo, Deborah; Christiansen, Lars Breum; MacFarlane, Duncan; Owen, Neville; Mitas, Josef; Troelsen, Jens; Aguinaga Ontoso, Inés  (Elsevier, 2015)   Artículo / Artikulua  

  The study's purpose was to examine age, gender, and education as potential moderators of the associations of perceived neighborhood environment variables with accelerometer-based moderate-to-vigorous physical activity ...

• Treatment effectiveness of intimate partner violence perpetration among patients in a drug-addiction programme 

  Fernández-Montalvo, Javier ; Arteaga Olleta, Alfonso ; López-Goñi, José Javier  (American Psychological Association, 2019)   Artículo / Artikulua  

  Objective: This article evaluates the treatment effectiveness of an integrated intervention compared to addiction treatment as usual (TAU) in reducing intimate partner violence perpetration (IPV-P) among patients in a ...

• Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines 

  Schiapparelli, Paula; Enguita Germán, Mónica; Balbuena, Jana; Rey, Juan A.; Lázcoz, Paula ; Castresana, Javier S. (Spandidos Publications, 2010)   Artículo / Artikulua  

  Neuroblastoma is the most common extracranial solid tumor in children, accounting for up to 10% of all childhood malignancies. Cellular heterogeneity is a hallmark of this embryonal cancer, as distinct neural crest lineages ...

• Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies 

  Lachén Montes, Mercedes; Zelaya, María Victoria; Segura, Víctor; Fernández Irigoyen, Joaquín; Santamaría, Enrique (Impact Journals, 2017)   Artículo / Artikulua  

  Alzheimer´s disease (AD) is characterized by progressive dementia, initially presenting olfactory dysfunction. Despite the olfactory bulb (OB) is the first central structure of the olfactory pathway, we lack a complete ...

• CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer 

  Martín Sánchez, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Blanco Luquin, Idoia; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Pérez Janices, Noemi; Escors, David; Megías, Diego (Impact Journals, 2017)   Artículo / Artikulua  

  The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation ...

• Perceived neighborhood environmental attributes associated with walking and cycling for transport among adult residents of 17 cities in 12 countries: the IPEN study 

  Kerr, Jacqueline; Emond, Jennifer A.; Badland, Hannah; Reis, Rodrigo S.; Sarmiento, Olga L.; Carlson, Jordan; Sallis, James F.; Cerin, Ester; Cain, Kelli L.; Aguinaga Ontoso, Inés  (National Institute of Environmental Health Science, 2016)   Artículo / Artikulua  

  Introduction: Prevalence of walking and cycling for transport is low and varies greatly across countries. Few studies have examined neighborhood perceptions related to walking and cycling for transport in different countries. ...

• Quality of life in Spanish advanced non-small-cell lung cancer patients: determinants of global QL and survival analyses 

  Arrarás, Juan Ignacio; Hernández, Berta; Martínez, Maite; Cambra Contin, Koldo; Rico, Mikel; Illarramendi, José Juan; Viudez, Antonio; Ibáñez Beroiz, B. ; Zarandona, Uxue; Martínez, Enrique; Vera, Ruth (Springer, 2016)   Artículo / Artikulua  

  Purpose: This paper studies the Quality of Life (QL) of Spanish advanced non-small-cell lung cancer (NSCLC) patients receiving platinum-doublet chemotherapy, compares our results with those from studies from other cultural ...

• A diphenyldiselenide derivative induces autophagy via JNK in HTB-54 lung cancer cells 

  Díaz, Marta; González, Roncesvalles; Plano, Daniel; Palop, Juan Antonio; Sanmartín, Carmen; Encío Martínez, Ignacio  (Wiley, 2017)   Artículo / Artikulua  

  Symmetric aromatic diselenides are potential anticancer agents with strong cytotoxic activity. In this study, the in vitro anticancer activities of a novel series of diarylseleno derivatives from the diphenyldiselenide ...

• Investigar es mirar lo que todos ven pero pensándolo de una manera diferente 

  López-Goñi, José Javier  (Asociación Proyecto Hombre, 2018)   Artículo / Artikulua  

  En este artículo se presentan los principales resultados de una línea de investigación que comenzó hace varios años el grupo de investigación en Psicología Clínica y Psicopatología de la Universidad Pública de Navarra en ...

• Promoter methylation of RASSF1A associates to adult secondary glioblastomas and pediatric glioblastomas 

  Muñoz, Jorge; Inda, María del Mar; Lázcoz, Paula ; Zazpe, Idoya; Fan, Xing; Alfaro, Jorge; Tuñón Álvarez, Teresa; Rey, Juan A.; Castresana, Javier S. (Hindawi / Wiley, 2012)   Artículo / Artikulua  

  While allelic losses and mutations of tumor suppressor genes implicated in the etiology of astrocytoma have been widely assessed, the role of epigenetics is still a matter of study. We analyzed the frequency of promoter ...

• Trends in hospital morbidity from Alzheimer's disease in the European Union, 2000-2014 

  Niu, Hao; Álvarez Álvarez, Ismael; Aguinaga Ontoso, Inés ; Guillén Grima, Francisco  (SAGE, 2018)   Artículo / Artikulua  

  Background: Alzheimer’s disease (AD) has become a concerning public health issue. We aimed to analyse the trends of hospital morbidity from AD in the European Union (EU) in the period 2000-2014. Methods: Data from ...

• CDH22 hypermethylation is an independent prognostic biomarker in breast cancer 

  Martín Sánchez, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero, David (BioMed Central, 2017)   Artículo / Artikulua  

  Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ...

• Network-driven proteogenomics unveils an aging-related imbalance in the olfactory IκBα-NFκB p65 complex functionality in Tg2576 Alzheimer’s disease mouse model 

  Palomino Alonso, Maialen; Lachén Montes, Mercedes; González Morales, Andrea; Ausín, Karina; Pérez Mediavilla, Alberto; Fernández Irigoyen, Joaquín; Santamaría, Enrique (MDPI, 2017)   Artículo / Artikulua  

  Olfaction is often deregulated in Alzheimer’s disease (AD) patients, and is also impaired in transgenic Tg2576 AD mice, which overexpress the Swedish mutated form of human amyloid precursor protein (APP). However, little ...

• High intensity interval- vs resistance or combined-training for improving cardiometabolic health in overweight adults (cardiometabolic HIIT-RT study): study protocol for a randomised controlled trial 

  Ramírez Vélez, Robinson; Hernández, Alejandra; Castro, Karem; Tordecilla Sanders, Alejandra; González Ruiz, Katherine; Correa Bautista, Jorge Enrique; Izquierdo Redín, Mikel ; García Hermoso, Antonio (BioMed Central, 2016)   Artículo / Artikulua  

  Background: Although evidence shows the positive health effects of physical activity, most of the adult population in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in ...

• Prevention of diabetes in overweight/obese children through a family based intervention program including supervised exercise (PREDIKID project): study protocol for a randomized controlled trial 

  Arenaza, Lide; Medrano, María; Amasene, María; Rodríguez Vigil, Beatriz; Díez, Ignacio; Graña, Manuel; Tobalina, Ignacio; Maiz, Edurne; Arteche, Edurne; Larrarte, Eider; Huybrechts, Inge; Davis, Catherine L.; Ruiz, Jonatan R.; Ortega, Francisco B.; Margareto, Javier; Labayen Goñi, Idoia (BioMed Central, 2017)   Artículo / Artikulua  

  Background: The global pandemic of obesity has led to an increased risk for prediabetes and type-2 diabetes (T2D). The aims of the current project are: (1) to evaluate the effect of a 22-week family based intervention program, ...

• Diferencias entre los intentos de suicidio y otras urgencias psiquiátricas hospitalarias 

  Goñi-Sarriés, Adriana; Janda-Galán, Lucía; Macaya-Aranguren, Patricia; Azcárate, Leire; López-Goñi, José Javier ; Álvarez, Ignacio (Fundación López Ibor, 2018)   Artículo / Artikulua  

  Introducción. No se han encontrado estudios en España que comparen el perfil de los pacientes atendidos en urgencias de psiquiatría por un intento de suicidio con los que acuden por otro motivo. El objetivo de este estudio ...

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