Envíos recientes

  • Bacillus thuringiensis toxins: an overview of their biocidal activity 

    Palma Dovis, Leopoldo Upna; Muñoz, Delia Upna; Berry, Colin; Murillo Martínez, Jesús Upna; Caballero Murillo, Primitivo Upna (MDPI, 2014)   Artículo / Artikulua  OpenAccess
    Bacillus thuringiensis (Bt) is a Gram positive, spore-forming bacterium that synthesizes parasporal crystalline inclusions containing Cry and Cyt proteins, some of which are toxic against a wide range of insect orders, ...
  • Molecular and insecticidal characterization of a novel cry-related protein from bacillus thuringiensis toxic against Myzus persicae 

    Palma Dovis, Leopoldo Upna; Muñoz Labiano, Delia; Berry, Colin; Murillo Martínez, Jesús Upna; Escudero, Iñigo de; Caballero Murillo, Primitivo Upna (MDPI, 2014)   Artículo / Artikulua  OpenAccess
    This study describes the insecticidal activity of a novel Bacillus thuringiensis Cry-related protein with a deduced 799 amino acid sequence (~89 kDa) and ~19% pairwise identity to the 95-kDa-aphidicidal protein (sequence ...
  • The Vip3Ag4 insecticidal protoxin from bacillus thuringiensis adopts a tetrameric configuration that is maintained on proteolysis 

    Palma Dovis, Leopoldo Upna; Scott, David J.; Harris, Gemma; Din, Salah-Ud; Williams, Thomas L.; Roberts, Oliver J.; Young, Mark T.; Caballero Murillo, Primitivo Upna; Berry, Colin (MDPI, 2017)   Artículo / Artikulua  OpenAccess
    The Vip3 proteins produced during vegetative growth by strains of the bacterium Bacillus thuringiensis show insecticidal activity against lepidopteran insects with a mechanism of action that may involve pore formation and ...
  • Immunization against small ruminant lentiviruses 

    Reina Arias, Ramsés Upna; Andrés Cara, Damián de; Amorena Zabalza, Beatriz Upna (MDPI, 2013)   Artículo / Artikulua  OpenAccess
    Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered ...
  • Effect of feeding regime on composting in bins 

    Storino, Francesco Upna; Menéndez Villanueva, Sergio Upna; Muro Erreguerena, Julio Upna; Aparicio Tejo, Pedro María Upna; Irigoyen Iriarte, Ignacio Upna (Taylor & Francis, 2017)   Artículo / Artikulua
    Composting in bins is one of the most practical home composting methods. There is currently a need for greater information to improve the management of the composting process and to create home composting programs, which ...
  • Gender-mediated differences in vertical transmission of a nucleopolyhedrovirus 

    Virto Garayoa, Cristina Upna; Zárate Chaves, Carlos Andrés; López Ferber, Miguel; Murillo Pérez, Rosa Upna; Caballero Murillo, Primitivo Upna; Williams, Trevor Upna (Public Library of Science, 2013)   Artículo / Artikulua  OpenAccess
    With the development of sensitive molecular techniques for detection of low levels of asymptomatic pathogens, it becoming clear that vertical transmission is a common feature of some insect pathogenic viruses, and likely ...
  • An effort to make sense of antisense transcription in bacteria 

    Lasa Uzcudun, Íñigo Upna; Toledo Arana, Alejandro Upna; Gingeras, Thomas R. (Taylor & Francis, 2012)   Artículo / Artikulua  OpenAccess
    Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some ...
  • Overlapping transcription and bacterial RNA removal 

    Lasa Uzcudun, Íñigo Upna; Villanueva San Martín, Maite Upna (National Academy of Sciences, 2014)   Artículo / Artikulua  OpenAccess
    The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput ...
  • Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals 

    Taglialegna, Agustina Upna; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Matthews, Steve; Penadés, José R.; Lasa Uzcudun, Íñigo Upna; Valle Turrillas, Jaione Upna (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
    Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
  • Amyloid structures as biofilm matrix scaffolds 

    Taglialegna, Agustina Upna; Lasa Uzcudun, Íñigo Upna; Valle Turrillas, Jaione Upna (American Society for Microbiology, 2016)   Artículo / Artikulua  OpenAccess
    Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward the recognition of amyloid fibers as common building block structures that confer stability to the exopolysaccharide matrix. ...
  • Genome-wide antisense transcription drives mRNA processing in bacteria 

    Lasa Uzcudun, Íñigo Upna; Toledo Arana, Alejandro Upna; Dobin, Alexander; Villanueva San Martín, Maite Upna; Ruiz de los Mozos Aliaga, Igor Upna; Vergara Irigaray, Marta Upna; Segura, Víctor; Fagegaltier, Delphine; Penadés, José R.; Valle Turrillas, Jaione Upna; Solano Goñi, Cristina Upna; Gingeras, Thomas R. (National Academy of Sciences, 2011)   Artículo / Artikulua  OpenAccess
    RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...
  • Salmonella biofilm development depends on the phosphorylation status of RcsB 

    Latasa Osta, Cristina Upna; García Martínez, Begoña Upna; Echeverz Sarasúa, Maite Upna; Toledo Arana, Alejandro Upna; Valle Turrillas, Jaione Upna; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina Upna; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
    The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...
  • Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor 

    Valle Turrillas, Jaione Upna; Latasa Osta, Cristina Upna; Gil Puig, Carmen Upna; Toledo Arana, Alejandro Upna; Solano Goñi, Cristina Upna; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
    The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
  • Coordinated cyclic-di-GMP repression of salmonella motility through YcgR and cellulose 

    Zorraquino Salvo, Violeta; García Martínez, Begoña Upna; Latasa Osta, Cristina Upna; Echeverz Sarasúa, Maite Upna; Toledo Arana, Alejandro Upna; Valle Turrillas, Jaione Upna; Lasa Uzcudun, Íñigo Upna; Solano Goñi, Cristina Upna (American Society for Microbiology, 2013)   Artículo / Artikulua  OpenAccess
    Cyclic di-GMP (c-di-GMP) is a secondary messenger that controls a variety of cellular processes, including the switch between a biofilm and a planktonic bacterial lifestyle. This nucleotide binds to cellular effectors in ...
  • Biofilm switch and immune response determinants at early stages of infection 

    Valle Turrillas, Jaione Upna; Solano Goñi, Cristina Upna; García Martínez, Begoña Upna; Toledo Arana, Alejandro Upna; Lasa Uzcudun, Íñigo Upna (Elsevier (Cell Press), 2013)   Artículo / Artikulua  OpenAccess
    Biofilm development is recognized as a major virulence factor underlying most chronic bacterial infections. When a biofilm community is established, planktonic cells growing in the surroundings of a tissue switch to a ...
  • Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection 

    Gil Puig, Carmen Upna; Solano Goñi, Cristina Upna; Burgui Erice, Saioa Upna; Latasa Osta, Cristina Upna; García Martínez, Begoña Upna; Toledo Arana, Alejandro Upna; Lasa Uzcudun, Íñigo Upna; Valle Turrillas, Jaione Upna (American Society for Microbiology, 2014)   Artículo / Artikulua  OpenAccess
    The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ...
  • Biofilm dispersion and quorum sensing 

    Solano Goñi, Cristina Upna; Echeverz Sarasúa, Maite Upna; Lasa Uzcudun, Íñigo Upna (Elsevier, 2014)   Artículo / Artikulua  OpenAccess
    Biofilm development and quorum sensing are closely interconnected processes. Biofilm formation is a cooperative group behaviour that involves bacterial populations living embedded in a self produced extracellular matrix. ...
  • Evaluation of surface microtopography engineered by direct laser interference for bacterial anti-biofouling 

    Valle Turrillas, Jaione Upna; Burgui Erice, Saioa Upna; Langheinrich, Denise; Gil Puig, Carmen Upna; Solano Goñi, Cristina Upna; Toledo Arana, Alejandro Upna; Helbig, Ralf; Lasagni, Andrés; Lasa Uzcudun, Íñigo Upna (2015)   Artículo / Artikulua  OpenAccess
    Biofilm formation by bacterial pathogens on the surface of medical and industrial settings is a 25 serious health problem. Modification of the biomaterial surface topography is a promising 26 strategy to prevent bacterial ...
  • Evaluation of a Salmonella strain lacking the secondary messenger c-di-GMP and RpoS as a live oral vaccine 

    Latasa Osta, Cristina Upna; Echeverz Sarasúa, Maite Upna; García Ona, Enrique Upna; Burgui Erice, Saioa Upna; Casares, Noelia; Hervás Stubbs, Sandra Upna; Lasarte, Juan José; Lasa Uzcudun, Íñigo Upna; Solano Goñi, Cristina Upna; García Martínez, Begoña Upna; Gil Puig, Carmen Upna (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
    Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through the consumption of contaminated food, with chicken and pig related products being key reservoirs of infection. Although numerous ...
  • Mechanisms of ammonium toxicity and the quest for tolerance 

    Esteban Terradillos, Raquel; Ariz, Idoia Upna; Cruz, Cristina; Morán Juez, José Fernando Upna (Elsevier, 2016)   Artículo / Artikulua
    Ammonium sensitivity of plants is a worldwide problem, constraining crop production. Prolonged application of ammonium as the sole nitrogen source may result in physiological and morphological disorders that lead to decreased ...

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