• Post-harvest light treatment increases expression levels of recombinant proteins in transformed plastids of potato tubers 

  Larraya Reta, Luis María; Fernández San Millán, Alicia; Ancín Rípodas, María; Farrán Blanch, Inmaculada ; Veramendi Charola, Jon (Wiley, 2015)   Artículo / Artikulua  

  Plastid genetic engineering represents an attractive system for the production of foreign proteins in plants. Although high expression levels can be achieved in leaf chloroplasts, the results for non-photosynthetic plastids ...

• Increased bioethanol production from commercial tobacco cultivars overexpressing thioredoxin f grown under field conditions 

  Farrán Blanch, Inmaculada ; Fernández San Millán, Alicia; Ancín Rípodas, María; Larraya Reta, Luis María; Veramendi Charola, Jon (Springer, 2014)   Artículo / Artikulua  

  Bioethanol is mainly produced from food crops such as sugar cane and maize while it has been held partly responsible for the rise of food commodity prices. Tobacco, integrated in biorefinery facilities for the extraction ...

• The fusion of Toxoplasma gondii SAG1 vaccine candidate to Leishmania infantum heat shock protein 83-kDa improves expression levels in tobacco chloroplasts 

  Albarracin, R; Laguía Becher, M; Farrán Blanch, Inmaculada ; Sander, V; Corigliano, M; Yácono, M; Pariani, S; Sánchez, E; Veramendi Charola, Jon; Clemente, M (Wiley, 2015)   Artículo / Artikulua  

  Chloroplast transformation technology has emerged as an alternative platform offering many advantages over nuclear transformation. SAG1 is the main surface antigen of the intracellular parasite Toxoplasma gondii and a ...

• Bacillus thuringiensis toxins: an overview of their biocidal activity 

  Palma Dovis, Leopoldo ; Muñoz, Delia ; Berry, Colin; Murillo Martínez, Jesús ; Caballero Murillo, Primitivo  (MDPI, 2014)   Artículo / Artikulua  

  Bacillus thuringiensis (Bt) is a Gram positive, spore-forming bacterium that synthesizes parasporal crystalline inclusions containing Cry and Cyt proteins, some of which are toxic against a wide range of insect orders, ...

• Molecular and insecticidal characterization of a novel cry-related protein from bacillus thuringiensis toxic against Myzus persicae 

  Palma Dovis, Leopoldo ; Muñoz Labiano, Delia; Berry, Colin; Murillo Martínez, Jesús ; Escudero, Iñigo de; Caballero Murillo, Primitivo  (MDPI, 2014)   Artículo / Artikulua  

  This study describes the insecticidal activity of a novel Bacillus thuringiensis Cry-related protein with a deduced 799 amino acid sequence (~89 kDa) and ~19% pairwise identity to the 95-kDa-aphidicidal protein (sequence ...

• The Vip3Ag4 insecticidal protoxin from bacillus thuringiensis adopts a tetrameric configuration that is maintained on proteolysis 

  Palma Dovis, Leopoldo ; Scott, David J.; Harris, Gemma; Din, Salah-Ud; Williams, Thomas L.; Roberts, Oliver J.; Young, Mark T.; Caballero Murillo, Primitivo ; Berry, Colin (MDPI, 2017)   Artículo / Artikulua  

  The Vip3 proteins produced during vegetative growth by strains of the bacterium Bacillus thuringiensis show insecticidal activity against lepidopteran insects with a mechanism of action that may involve pore formation and ...

• Immunization against small ruminant lentiviruses 

  Reina Arias, Ramsés ; Andrés Cara, Damián de; Amorena Zabalza, Beatriz  (MDPI, 2013)   Artículo / Artikulua  

  Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered ...

• Effect of feeding regime on composting in bins 

  Storino, Francesco ; Menéndez Villanueva, Sergio ; Muro Erreguerena, Julio ; Aparicio Tejo, Pedro María ; Irigoyen Iriarte, Ignacio  (Taylor & Francis, 2017)   Artículo / Artikulua

  Composting in bins is one of the most practical home composting methods. There is currently a need for greater information to improve the management of the composting process and to create home composting programs, which ...

• Gender-mediated differences in vertical transmission of a nucleopolyhedrovirus 

  Virto Garayoa, Cristina ; Zárate Chaves, Carlos Andrés; López Ferber, Miguel; Murillo Pérez, Rosa ; Caballero Murillo, Primitivo ; Williams, Trevor  (Public Library of Science, 2013)   Artículo / Artikulua  

  With the development of sensitive molecular techniques for detection of low levels of asymptomatic pathogens, it becoming clear that vertical transmission is a common feature of some insect pathogenic viruses, and likely ...

• An effort to make sense of antisense transcription in bacteria 

  Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro ; Gingeras, Thomas R. (Taylor & Francis, 2012)   Artículo / Artikulua  

  Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some ...

• Overlapping transcription and bacterial RNA removal 

  Lasa Uzcudun, Íñigo ; Villanueva San Martín, Maite  (National Academy of Sciences, 2014)   Artículo / Artikulua  

  The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput ...

• Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals 

  Taglialegna, Agustina ; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Matthews, Steve; Penadés, José R.; Lasa Uzcudun, Íñigo ; Valle Turrillas, Jaione  (Public Library of Science, 2016)   Artículo / Artikulua  

  Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...

• Amyloid structures as biofilm matrix scaffolds 

  Taglialegna, Agustina ; Lasa Uzcudun, Íñigo ; Valle Turrillas, Jaione  (American Society for Microbiology, 2016)   Artículo / Artikulua  

  Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward the recognition of amyloid fibers as common building block structures that confer stability to the exopolysaccharide matrix. ...

• Genome-wide antisense transcription drives mRNA processing in bacteria 

  Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro ; Dobin, Alexander; Villanueva San Martín, Maite ; Ruiz de los Mozos Aliaga, Igor ; Vergara Irigaray, Marta ; Segura, Víctor; Fagegaltier, Delphine; Penadés, José R.; Valle Turrillas, Jaione ; Solano Goñi, Cristina ; Gingeras, Thomas R. (National Academy of Sciences, 2011)   Artículo / Artikulua  

  RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...

• Salmonella biofilm development depends on the phosphorylation status of RcsB 

  Latasa Osta, Cristina ; García Martínez, Begoña ; Echeverz Sarasúa, Maite ; Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo  (American Society for Microbiology, 2012)   Artículo / Artikulua  

  The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...

• Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor 

  Valle Turrillas, Jaione ; Latasa Osta, Cristina ; Gil Puig, Carmen ; Toledo Arana, Alejandro ; Solano Goñi, Cristina ; Penadés, José R.; Lasa Uzcudun, Íñigo  (Public Library of Science, 2012)   Artículo / Artikulua  

  The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...

• Coordinated cyclic-di-GMP repression of salmonella motility through YcgR and cellulose 

  Zorraquino Salvo, Violeta; García Martínez, Begoña ; Latasa Osta, Cristina ; Echeverz Sarasúa, Maite ; Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Lasa Uzcudun, Íñigo ; Solano Goñi, Cristina  (American Society for Microbiology, 2013)   Artículo / Artikulua  

  Cyclic di-GMP (c-di-GMP) is a secondary messenger that controls a variety of cellular processes, including the switch between a biofilm and a planktonic bacterial lifestyle. This nucleotide binds to cellular effectors in ...

• Biofilm switch and immune response determinants at early stages of infection 

  Valle Turrillas, Jaione ; Solano Goñi, Cristina ; García Martínez, Begoña ; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo  (Elsevier (Cell Press), 2013)   Artículo / Artikulua  

  Biofilm development is recognized as a major virulence factor underlying most chronic bacterial infections. When a biofilm community is established, planktonic cells growing in the surroundings of a tissue switch to a ...

• Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection 

  Gil Puig, Carmen ; Solano Goñi, Cristina ; Burgui Erice, Saioa ; Latasa Osta, Cristina ; García Martínez, Begoña ; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo ; Valle Turrillas, Jaione  (American Society for Microbiology, 2014)   Artículo / Artikulua  

  The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ...

• Biofilm dispersion and quorum sensing 

  Solano Goñi, Cristina ; Echeverz Sarasúa, Maite ; Lasa Uzcudun, Íñigo  (Elsevier, 2014)   Artículo / Artikulua  

  Biofilm development and quorum sensing are closely interconnected processes. Biofilm formation is a cooperative group behaviour that involves bacterial populations living embedded in a self produced extracellular matrix. ...

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