• Anti-inflammatory and antioxidant capacity of a fruit and vegetable-based nutraceutical measured by urinary oxylipin concentration in a healthy population: a randomized, double-blind, placebo-controlled clinical trial 

      Arcusa, Raúl; Carrillo, Juan Ángel; Cerdá, Begoña; Durand, Thierry; Gil-Izquierdo, Ángel; Medina, Sonia; Galano, Jean-Marie; Villaño Valencia, Débora; Marhuenda, Javier; Zafrilla, Pilar (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Oxylipins, lipid biomarkers of inflammation are considered the gold standard method to evaluate the inflammatory and antioxidant status. The aim of the present study was to investigate whether the administration of a ...
    • Anti-inflammatory and chondroprotective effects induced by phenolic compounds from onion waste extracts in ATDC-5 chondrogenic cell line 

      Paesa, Mónica; Ancín Azpilicueta, Carmen Upna Orcid; Velderrain-Rodríguez, Gustavo; Martín-Belloso, Olga; Gualillo, Oreste; Osada, Jesús; Rodríguez Yoldi, María Jesús; Mendoza, Gracia (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Osteoarthritis is a prevalent degenerative condition that is closely related to the destruction and inflammation of cartilage. The high prevalence of this pathology exhorts researchers to search for novel therapeutic ...
    • The dietary inflammatory index and hepatic health in the US adult population 

      Ramírez Vélez, Robinson; García Hermoso, Antonio; Izquierdo Redín, Mikel; Correa Rodríguez, María (The British Dietetic Association Ltd, 2021)   Artículo / Artikulua  OpenAccess
      Background: There is limited evidence on the role of an anti‐/pro‐inflammatory diet in the prevention of non‐alcoholic fatty liver disease (NAFLD). We aimed (i) to assess the anti‐inflammatory diet profile and its association ...
    • Effects of exercise interventions on inflammatory parameters in acutely hospitalized older patients: a systematic review and meta-analysis of randomized controlled trials 

      Ramírez Vélez, Robinson Upna Orcid; García Hermoso, Antonio; Martínez Velilla, Nicolás Upna Orcid; Zambom Ferraresi, Fabrício Upna Orcid; Saez de Asteasu, Mikel L.; Recarey Rodríguez, Anel Eduardo Upna; Izquierdo Redín, Mikel Upna Orcid (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      The purpose of this systematic review and meta-analysis was to appraise the acute effects of exercise training on inflammatory parameters in hospitalized older adults. We conducted a systematic review using the Preferred ...
    • Elovanoids counteract inflammatory signaling, autophagy, endoplasmic reticulum stress, and eenescence gene programming in human nasal epithelial cells exposed to allergens 

      Resano Lizaldre, Alfredo; Bhattacharjee, Surjyadipta; Barajas Vélez, Miguel Ángel Upna Orcid; Do, Khanh V.; Aguado Jiménez, Roberto Upna Orcid; Rodríguez, David; Palacios Peláez, Ricardo; Bazán, Nicolás G. (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      To contribute to further understanding the cellular and molecular complexities of inflammatory-immune responses in allergic disorders, we have tested the pro-homeostatic elovanoids (ELV) in human nasal epithelial cells ...
    • Higher cardiorespiratory fitness levels may attenuate the detrimental association between weight status, metabolic phenotype and C-reactive protein in adolescents—a multi-cohort study 

      Agostinis-Sobrinho, César; Rosário, Rafaela; Izquierdo Redín, Mikel Upna Orcid; García Hermoso, Antonio; Ramírez Vélez, Robinson Upna Orcid (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Results from several studies show that only obese, unfit subjects, but not obese, fit subjects, are at higher mortality risk than are normal-weight fit subjects. The aim of the study was two-fold: (1) to examine the ...
    • Impaired LXRα phosphorylation attenuates progression of fatty liver disease 

      Bécares, Natalia; Gage, Matthew C.; Voisin, Maud; Shrestha, Elina; Martín-Gutiérrez, Lucía; Liang, Ning; Louie, Rikah; Pourcet, Benoît; Pello, Óscar M.; Luong, Tu Vinh; Goñi Irigoyen, Saioa Upna Orcid; Pichardo-Almarza, César; Røberg-Larsen, Hanne; Díaz-Zuccarini, Vanessa; Steffensen, Knut R.; O’Brien, Alastair; Garabedian, Michael J.; Rombouts, Krista; Treuter, Eckardt; Pineda-Torra, Inés (Cell Press, 2019)   Artículo / Artikulua  OpenAccess
      Non-alcoholic fatty liver disease (NAFLD) is a very common indication for liver transplantation. How fat-rich diets promote progression from fatty liver to more damaging inflammatory and fibrotic stages is poorly understood. ...
    • Inflammation in COVID-19 and the effects of non-pharmacological interventions during the pandemic: a review 

      Clemente Suárez, Vicente Javier; Bustamante Sanchez, Álvaro; Tornero Aguilera, José Francisco; Ruisoto, Pablo Upna Orcid; Mielgo Ayuso, Juan (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the coronavirus disease 2019 (COVID-19) pandemic that hit the health systems worldwide hard, causing a collapse of healthcare systems. One of the main ...
    • Metabolic health, mitochondrial fitness, physical activity, and cancer 

      Clemente Suárez, Vicente Javier; Martín Rodríguez, Alexandra; Redondo Flórez, Laura; Ruisoto, Pablo Upna Orcid; Navarro Jiménez, Eduardo; Ramos Campo, Domingo Jesús; Tornero Aguilera, José Francisco (MDPI, 2023)   Artículo / Artikulua  OpenAccess
      Cancer continues to be a significant global health issue. Traditional genetic-based approaches to understanding and treating cancer have had limited success. Researchers are increasingly exploring the impact of the ...
    • Plasma inflammatory biomarkers and anorexia of ageing among community-dwelling older adults: an exploratory analysis of the MAPT Study 

      Sánchez Sánchez, Juan Luis Upna; Guyonnet, Sophie; Lucas, Alexandre; Parini, Angelo; Rolland, Y.; Souto Barreto, P. de (Springer, 2023)   Artículo / Artikulua  OpenAccess
      Anorexia of aging and biological aging might share physiological underpinnings. The aim of this secondary analysis was to investigate the associations between circulating inflammation-related markers and anorexia of aging ...
    • Resistance training and clinical status in patients with postdischarge symptoms after COVID-19: protocol for a randomized controlled crossover trial 'The EXER-COVID Crossover Study'. 

      Ramírez Vélez, Robinson; Oteiza Olaso, Julio Upna Orcid; Casas Fernández de Tejerina, Juan Manuel; García Alonso, Nora; Legarra Gorgoñón, Gaizka; Oscoz Ochandorena, Sergio; Arasanz Esteban, Hugo; García Alonso, Yesenia Upna Orcid; Correa Rodríguez, María; Izquierdo Redín, Mikel (2022)   Artículo / Artikulua  OpenAccess
      Background: physical exercise induces a coordinated response of multiple organ systems, including the immune system. In fact, it has been proposed that physical exercise may modulate the immune system. However, the ...
    • Sex-specific role of galectin-3 in aortic stenosis 

      Matilla Cuenca, Lara; Martín Núñez, Ernesto; Garaikoetxea Zubillaga, Mattie; Navarro, Adela; Tamayo Rodríguez, Ibai; Fernández Celis, Amaya; Gaínza Calleja, Alicia; Fernández Irigoyen, Joaquín Upna Orcid; Santamaría, Enrique; Muntendam, Pieter; Álvarez, Virginia; Sádaba Sagredo, Rafael; Jover, Eva; López Andrés, Natalia (BMC, 2023)   Artículo / Artikulua  OpenAccess
      Background: Aortic stenosis (AS) is characterized by infammation, fbrosis, osteogenesis and angiogenesis. Men and women develop these mechanisms diferently. Galectin-3 (Gal-3) is a pro-infammatory and pro-osteogenic lectin ...
    • Soluble ST2 as a new oxidative stress and inflammation marker in metabolic syndrome 

      Roy, Ignacio; Jover, Eva; Matilla Cuenca, Lara; Álvarez, Virginia; Fernández Celis, Amaya; Beunza, Maite; Escribano, Elena; Gaínza Calleja, Alicia; Sádaba Sagredo, Rafael; López Andrés, Natalia (MDPI, 2023)   Artículo / Artikulua  OpenAccess
      Background: Metabolic syndrome (MS) is a complex and prevalent disorder. Oxidative stress and inflammation might contribute to the progression of MS. Soluble ST2 (sST2) is an attractive and druggable molecule that sits at ...
    • Targeting fatty acid-binding protein 4 improves pathologic features of aortic stenosis 

      Garaikoetxea Zubillaga, Mattie; Martín Núñez, Ernesto; Navarro, Adela; Matilla Cuenca, Lara; Fernández Celis, Amaya; Arrieta Paniagua, Vanessa; García Peña, Amaia; Gaínza Calleja, Alicia; Álvarez, Virginia; Sádaba Sagredo, Rafael; Jover, Eva; López Andrés, Natalia (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Aortic stenosis (AS) is a fibrocalcific disease of the aortic valves (AVs). Sex-differences in AS pathophysiology have recently been described. High levels of fatty acid-binding protein 4 (FAPB4) in atherosclerotic plaques ...
    • Th17-related genes and celiac disease susceptibility 

      Medrano, Luz María; García Magariños, Manuel Upna Orcid; Dema, Barbara; Espino, Laura; Maluenda, Carlos; Polanco, Isabel; Figueredo, María Ángeles; Fernández Arquero, Miguel; Núñez, Concepción (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      Th17 cells are known to be involved in several autoimmune or inflammatory diseases. In celiac disease (CD), recent studies suggest an implication of those cells in disease pathogenesis. We aimed at studying the role of ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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