Listar Artículos de revista - Aldizkari artikuluak por autor UPNA "Lasa Uzcudun, Íñigo"

Mostrando ítems 21-40 de 58

    • The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation 

      Toledo Arana, Alejandro Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Arrizubieta Balerdi, María Jesús Upna; Cucarella, Carme; Lamata, Marta; Amorena Zabalza, Beatriz Upna; Leiva, José; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2001)   Artículo / Artikulua  OpenAccess
      The enterococcal surface protein, Esp, is a high-molecular-weight surface protein of unknown function whose frequency is significantly increased among infection-derived Enterococcus faecalis isolates. In this work, a ...

    • Evaluation of a Salmonella strain lacking the secondary messenger c-di-GMP and RpoS as a live oral vaccine 

      Latasa Osta, Cristina Upna; Echeverz Sarasúa, Maite Upna Orcid; García Ona, Enrique Upna; Burgui Erice, Saioa Upna Orcid; Casares, Noelia; Hervás Stubbs, Sandra Upna; Lasarte, Juan José; Lasa Uzcudun, Íñigo Upna Orcid; Solano Goñi, Cristina Upna Orcid; García Martínez, Begoña Upna Orcid; Gil Puig, Carmen Upna Orcid (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
      Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through the consumption of contaminated food, with chicken and pig related products being key reservoirs of infection. Although numerous ...

    • Evaluation of surface microtopography engineered by direct laser interference for bacterial anti-biofouling 

      Valle Turrillas, Jaione Upna Orcid; Burgui Erice, Saioa Upna Orcid; Langheinrich, Denise; Gil Puig, Carmen Upna Orcid; Solano Goñi, Cristina Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Helbig, Ralf; Lasagni, Andrés; Lasa Uzcudun, Íñigo Upna Orcid (2015)   Artículo / Artikulua  OpenAccess
      Biofilm formation by bacterial pathogens on the surface of medical and industrial settings is a 25 serious health problem. Modification of the biomaterial surface topography is a promising 26 strategy to prevent bacterial ...

    • Expression of the biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process 

      Cucarella, Carme; Tormo Más, María Ángeles; Knecht, Erwin; Amorena Zabalza, Beatriz Upna; Lasa Uzcudun, Íñigo Upna Orcid; Foster, Timothy J.; Penadés, José R. (American Society for Microbiology, 2002)   Artículo / Artikulua  OpenAccess
      The adherence of Staphylococcus aureus to soluble proteins and extracellular-matrix components of the host is one of the key steps in the pathogenesis of staphylococcal infections. S. aureus presents a family of adhesins ...

    • The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice 

      San Román Aberasturi, Beatriz Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria Upna; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña Upna Orcid; Andrés, Ximena de; Zabaleta, Virginia Upna; Mansilla, Cristina; Farrán Blanch, Inmaculada Upna Orcid (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...

    • Fitness cost evolution of natural plasmids of staphylococcus aureus 

      Dorado Morales, Pedro Upna Orcid; Garcillán-Barcia, María Pilar; Lasa Uzcudun, Íñigo Upna Orcid; Solano Goñi, Cristina Upna Orcid (American Society for Microbiology, 2021)   Artículo / Artikulua  OpenAccess
      Plasmids have largely contributed to the spread of antimicrobial resistance genes among Staphylococcus strains. Knowledge about the fitness cost that plasmids confer on clinical staphylococcal isolates and the coevolutionary ...

    • Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella 

      Solano Goñi, Cristina Upna Orcid; García Martínez, Begoña Upna Orcid; Latasa Osta, Cristina Upna; Toledo Arana, Alejandro Upna Orcid; Zorraquino Salvo, Violeta; Valle Turrillas, Jaione Upna Orcid; Casals, Joan; Pedroso, Enrique; Lasa Uzcudun, Íñigo Upna Orcid (National Academy of Sciences, 2009)   Artículo / Artikulua  OpenAccess
      Bacteria have developed an exclusive signal transduction system involving multiple diguanylate cyclase and phosphodiesterase domain-containing proteins (GGDEF and EAL/HD-GYP, respectively) that modulate the levels of the ...

    • Genome-wide antisense transcription drives mRNA processing in bacteria 

      Lasa Uzcudun, Íñigo Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Dobin, Alexander; Villanueva San Martín, Maite Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Vergara Irigaray, Marta Upna; Segura, Víctor; Fagegaltier, Delphine; Penadés, José R.; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Gingeras, Thomas R. (National Academy of Sciences, 2011)   Artículo / Artikulua  OpenAccess
      RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...

    • The impact of two-component sensorial network in staphylococcal speciation 

      Rapún Araiz, Beatriz Upna Orcid; Haag, Andreas F.; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Elsevier, 2020)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. ...

    • Inhibiting the two‑component system GraXRS with verteporfin to combat Staphylococcus aureus infections 

      Prieto Mariscal, Juana María; Rapún Araiz, Beatriz Upna Orcid; Gil Puig, Carmen Upna Orcid; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid; Latasa Osta, Cristina Upna (Nature Research, 2020)   Artículo / Artikulua  OpenAccess
      Infections caused by Staphylococcus aureus pose a serious and sometimes fatal health issue. With the aim of exploring a novel therapeutic approach, we chose GraXRS, a Two-Component System (TCS) that determines bacterial ...

    • Killing niche competitors by remote-control bacteriophage induction 

      Selva, Laura; Viana, David; Regev Yochay, Gili; Trzcinski, Krzysztof; Corpa, Juan Manuel; Lasa Uzcudun, Íñigo Upna Orcid; Novick, Richard P.; Penadés, José R. (National Academy of Sciences, 2009)   Artículo / Artikulua  OpenAccess
      A surprising example of interspecies competition is the production by certain bacteria of hydrogen peroxide at concentrations that are lethal for others. A case in point is the displacement of Staphylococcus aureus by ...

    • Lack of the PGA exopolysaccharide in Salmonella as an adaptive trait for survival in the host 

      Echeverz Sarasúa, Maite Upna Orcid; García Martínez, Begoña Upna Orcid; Sabalza Baztán, Amaia Upna; Valle Turrillas, Jaione Upna Orcid; Gabaldón Estevan, Juan Antonio; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      Many bacteria build biofilm matrices using a conserved exopolysaccharide named PGA or PNAG (poly-β-1,6-N-acetyl-D-glucosamine). Interestingly, while E. coli and other members of the family Enterobacteriaceae encode the ...

    • Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands 

      Tormo Más, María Ángeles; Mir, Ignacio; Shrestha, Archana; Tallent, Sandra M.; Campoy Sánchez, Susana; Lasa Uzcudun, Íñigo Upna Orcid; Barbé, Jordi; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Nature Research, 2010)   Artículo / Artikulua  OpenAccess
      Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of ∼15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently ...

    • Near-infrared fluorescence imaging as an alternative to bioluminescent bacteria to monitor biomaterial-associated infections 

      Dinjaski, Nina; Shalu, Suri; Valle Turrillas, Jaione Upna Orcid; Lehman, Susan M.; Lasa Uzcudun, Íñigo Upna Orcid; Prieto, María Auxiliadora; García, Andrés J. (Elsevier, 2014)   Artículo / Artikulua  OpenAccess
      Biomaterial-associated infection is one of the most common complications related with the implantation of any biomedical device. Several in vivo imaging platforms have emerged as powerful diagnostic tools to longitudinally ...

    • Noncontiguous operon is a genetic organization for coordinating bacterial gene expression 

      Sáenz Lahoya, S.; Bitarte, Nerea Upna; García, Beñat; Burgui Erice, Saioa Upna Orcid; Vergara Irigaray, Marta Upna; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (National Academy of Sciences, 2019)   Artículo / Artikulua  OpenAccess
      Bacterial genes are typically grouped into operons defined as clusters of adjacent genes encoding for proteins that fill related roles and are transcribed into a single polycistronic mRNA molecule. This simple organization ...

    • Overlapping transcription and bacterial RNA removal 

      Lasa Uzcudun, Íñigo Upna Orcid; Villanueva San Martín, Maite Upna Orcid (National Academy of Sciences, 2014)   Artículo / Artikulua  OpenAccess
      The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput ...

    • Protein A-mediated multicellular behavior in Staphylococcus aureus 

      Merino, Nekane Upna; Toledo Arana, Alejandro Upna Orcid; Vergara Irigaray, Marta Upna; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Calvo, Enrique; Lopez, Juan Antonio; Foster, Timothy J.; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
      The capacity of Staphylococcus aureus to form biofilms on host tissues and implanted medical devices is one of the major virulence traits underlying persistent and chronic infections. The matrix in which S. aureus cells ...

    • A pyrene-inhibitor fluorescent probe with large stokes shift for the staining of Aβ1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing staphylococcus aureus biofilms 

      Mahía, Alejandro; Conde-Giménez, María; Salillas, Sandra; Pallarés, Irantzu; Galano-Frutos, Juan J.; Lasa Uzcudun, Íñigo Upna Orcid; Ventura, Salvador; Díaz-de-Villegas, María D.; Gálvez, José A.; Sancho, Javier (Springer, 2019)   Artículo / Artikulua  OpenAccess
      Amyloid fibrils formed by a variety of peptides are biological markers of different human diseases, such as Alzheimer, Parkinson or Type II diabetes, and are structural constituents of bacterial ...

    • The regulon of the RNA chaperone CspA and its auto-regulation in Staphylococcus aureus 

      Caballero Sánchez, Carlos Upna; Menéndez Gil, Pilar; Catalán Moreno, Arancha; Vergara Irigaray, Marta Upna; García Martínez, Begoña Upna Orcid; Segura, Víctor; Irurzun Domínguez, Naiara; Villanueva San Martín, Maite Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Toledo Arana, Alejandro Upna Orcid (Oxford University Press, 2018)   Artículo / Artikulua  OpenAccess
      RNA-binding proteins (RBPs) are essential to finetune gene expression. RBPs containing the coldshock domain are RNA chaperones that have been extensively studied. However, the RNA targets and specific functions for ...

    • Relevant role of fibronectin-binding proteins in Staphylococcus aureus biofilm-associated foreign-body infections 

      Vergara Irigaray, Marta Upna; Valle Turrillas, Jaione Upna Orcid; Merino, Nekane Upna; Latasa Osta, Cristina Upna; García Martínez, Begoña Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2009)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains ...
      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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