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Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch
(EMBO Press, 2021)
info:eu-repo/semantics/article,
The Staphylococcal Bap proteins sense environmental signals (such as pH, [Ca2+]) to build amyloid scaffold biofilm matrices via unknown mechanisms. We here report the crystal structure of the aggregation-prone region of ...
RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
(Oxford University Press, 2011)
Artículo / Artikulua,
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
Functional analysis of intergenic regulatory regions of genes encoding surface adhesins in Staphylococcus aureus isolates from periprosthetic joint infections
(Elsevier, 2022)
Artículo / Artikulua,
Staphylococcus aureus is a leading cause of prosthetic joint infections (PJI). Surface adhesins play an important
role in the primary attachment to plasma proteins that coat the surface of prosthetic devices after ...
Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection
(American Society for Microbiology, 2014)
Artículo / Artikulua,
The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due
to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ...
Evaluation of a Salmonella strain lacking the secondary messenger c-di-GMP and RpoS as a live oral vaccine
(Public Library of Science, 2016)
Artículo / Artikulua,
Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through
the consumption of contaminated food, with chicken and pig related products being key reservoirs
of infection. Although numerous ...
Evaluation of surface microtopography engineered by direct laser interference for bacterial anti-biofouling
(2015)
Artículo / Artikulua,
Biofilm formation by bacterial pathogens on the surface of medical and industrial settings is a 25 serious health problem. Modification of the biomaterial surface topography is a promising 26 strategy to prevent bacterial ...
Biofilm dispersion and quorum sensing
(Elsevier, 2014)
Artículo / Artikulua,
Biofilm development and quorum sensing are closely interconnected processes. Biofilm
formation is a cooperative group behaviour that involves bacterial populations living
embedded in a self produced extracellular matrix. ...
Staphylococcus aureus susceptibility to complestatin and corbomycin depends on the VraSR two-component system
(American Society for Microbiology, 2023)
Artículo / Artikulua,
The overuse of antibiotics in humans and livestock has driven the emergence and spread of antimicrobial resistance and has therefore prompted research
on the discovery of novel antibiotics. Complestatin (Cm) and corbomycin ...
Amyloid structures as biofilm matrix scaffolds
(American Society for Microbiology, 2016)
Artículo / Artikulua,
Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward the recognition of amyloid fibers
as common building block structures that confer stability to the exopolysaccharide matrix. ...
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...