Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching

Cardona-Maya, Yamile; Socorro Leránoz, Abián Bentor; Del Villar, Ignacio; Cruz, José Luis; Corres Sanz, Jesús María; Botero-Cadavid, Juan F.

doi:10.1016/j.snb.2018.03.002

dc.creator	Cardona-Maya, Yamile	es_ES
dc.creator	Socorro Leránoz, Abián Bentor	es_ES
dc.creator	Del Villar, Ignacio	es_ES
dc.creator	Cruz, José Luis	es_ES
dc.creator	Corres Sanz, Jesús María	es_ES
dc.creator	Botero-Cadavid, Juan F.	es_ES
dc.date.accessioned	2018-03-27T10:43:58Z
dc.date.available	2020-03-07T00:00:10Z
dc.date.issued	2018
dc.identifier.issn	0925-4005
dc.identifier.uri	https://hdl.handle.net/2454/28092
dc.description.abstract	The performance of E-SMS (Etched Singlemode-Multimode-Singlemode) optical fiber structures as immunosensors has been assessed by the implementation of antibody/antigen immunoassays. Through this procedure it has been proven that E-SMS structures are effective and suitable optical platforms for label-free biosensing. Using the phase shift and tracking the wavelength response it was found that the fabricated E-SMS devices exhibited limits of detection (LOD) down up to concentrations of 0.2mg/L of antigens in solution. This was achieved by coating the E-SMS with an antibody-based biolayer (goat IgG) that is able to determine the presence of anti-goat IgG antigen. Both a wavelength detection and a fast Fourier transform (FFT) analysis technique were used to perform this analysis. The FFT method showed similar results to those observed with the most traditional wavelength analysis, but with the advantage of a simpler detection system that makes unnecessary the use of sophisticated optical interrogators.	en
dc.description.sponsorship	This work was supported in part by the Spanish Ministry of Education and Science - FEDER TEC 2016- 78047 and by the Government of Navarre through its projects with references: 2016/PI044, 2016/PC025 and 2016/PC026. This work was supported in part by the Colombian Administrative Department of Science, Technology and Innovation - Colciencias, through the Program for national doctorates, calling 617 of 2013, and by the project “BIOSENSORES A FIBRA ÓPTICA PARA LA DETECCIÓN RÁPIDA DE ENFERMEDADES” supported by the Universidad Nacional de Colombia (Hermes code 40834).	en
dc.format.mimetype	application/pdf	en
dc.language.iso	eng	en
dc.publisher	Elsevier	en
dc.relation.ispartof	Sensors and Actuators B: Chemical, Vol. 265 (2018) pgs. 10–19	en
dc.rights	© 2018 Elsevier B.V. The manuscript version is made available under the CC BY-NC-ND 4.0 license.	en
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject	Fiber-optic biosensors	en
dc.subject	Label-free immunosensors	en
dc.subject	Etched-SMS	en
dc.subject	Bio-layer	en
dc.subject	IgG/Anti-IgG binding	en
dc.title	Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching	en
dc.type	Artículo / Artikulua	es
dc.type	info:eu-repo/semantics/article	en
dc.contributor.department	Ingeniería Eléctrica y Electrónica	es_ES
dc.contributor.department	Ingeniaritza Elektrikoa eta Elektronikoa	eu
dc.rights.accessRights	Acceso abierto / Sarbide irekia	es
dc.rights.accessRights	info:eu-repo/semantics/openAccess	en
dc.embargo.terms	2020-03-07
dc.identifier.doi	10.1016/j.snb.2018.03.002
dc.relation.projectID	info:eu-repo/grantAgreement/ES/1PE/TEC2016-78047	en
dc.relation.publisherversion	https://doi.org/10.1016/j.snb.2018.03.002
dc.type.version	Versión aceptada / Onetsi den bertsioa	es
dc.type.version	info:eu-repo/semantics/acceptedVersion	en
dc.contributor.funder	Gobierno de Navarra / Nafarroako Gobernua 2016/PI044	es
dc.contributor.funder	Gobierno de Navarra / Nafarroako Gobernua 2016/PC025	es
dc.contributor.funder	Gobierno de Navarra / Nafarroako Gobernua 2016/PC026	es

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