A parametric model for studying the aorta hemodynamics by means of the computational fluid dynamics
Fecha
2020Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión aceptada / Onetsi den bertsioa
Identificador del proyecto
Impacto
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10.1016/j.jbiomech.2020.109691
Resumen
Perturbed aorta hemodynamics, as for the carotid and the coronary artery, has been identified as
potential predicting factor for cardiovascular diseases. In this study, we propose a parametric study
based on the computational fluid dynamics with the aim of providing information regarding aortic
disease. In particular, the blood flow inside a parametrized aortic arch is computed as a function o ...
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Perturbed aorta hemodynamics, as for the carotid and the coronary artery, has been identified as
potential predicting factor for cardiovascular diseases. In this study, we propose a parametric study
based on the computational fluid dynamics with the aim of providing information regarding aortic
disease. In particular, the blood flow inside a parametrized aortic arch is computed as a function of
morphological changes of baseline aorta geometry. Flow patterns, wall shear stress, time average wall
shear stress and oscillatory shear index were calculated during the cardiac cycle. The influence of
geometrical changes on the hemodynamics and on these variables was evaluated. The results suggest that the distance between inflow and aortic arch and the angle between aortic arch
and descending trunk are the most influencing parameters regarding the WSS-related
indices while the effect of the inlet diameter seems limited. In particular, an increase
of the aforementioned distance produces a reduction of the spatial distribution of the
higher values of the time average wall shear stress and of the oscillatory shear index
independently on the other two parameters while an increase of the angle produce an
opposite effect. Moreover, as expected, the analysis of the wall shear stress descriptors suggests that the inlet diameter influences only the flow intensity. As conclusion, the
proposed parametric study can be used to evaluate the aorta hemodynamics and could be also
applied in the future, for analyzing pathological cases and virtual situations, such as pre- and/or
post-operative cardiovascular surgical states that present enhanced changes in the aorta morphology
yet promoting important variations on the considered indexes. [--]
Materias
Aortic hemodynamics,
Wall shear stress descriptors,
Finite volume analysis,
Barametric aorta design,
Computational fluid dynamics
Editor
Elsevier
Publicado en
Journal of Biomechanics 103 (2020) 109691
Departamento
Universidad Pública de Navarra. Departamento de Ingeniería /
Nafarroako Unibertsitate Publikoa. Ingeniaritza Saila
Versión del editor
Entidades Financiadoras
The authors gratefully acknowledge the research support of the Spanish Ministry of Econ339 omy and Competitiveness through the research projects DPI-2016-76630-C2-1-R and DPI2017-83259-R (AEI/FEDER,UE). The support of the Instituto de Salud Carlos III (ISCIII) through
341 the CIBER-BBN initiative and the project Patient-Specific Modelling of the Aortic valve replacement: Advance towards a Decision Support System (DeSSAValve) is highly appreciated.