Browsing by Author "Urdaneta, Elena"

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    Efecto de la alimentación de pollos en crecimiento con alubias (Phaseolus vulgaris. L. var. Pinto) extrusionadas en el músculo para la carne
    (2006) Ortín Hernández, María Carmen; Marzo Pérez, Florencio; Urdaneta, Elena; Escuela Técnica Superior de Ingenieros Agrónomos; Nekazaritza Ingeniarien Goi Mailako Eskola Teknikoa; Ciencias del Medio Natural; Natura Ingurunearen Zientziak
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    PublicationOpen Access
    Effect of dietary quercetin and sphingomyelin on intestinal nutrient absorption and animal growth
    (Cambridge University Press, 2006) Barrenetxe, Jaione; Aranguren Garacochea, Patricia; Grijalba, A.; Martínez-Peñuela, J. M.; Marzo Pérez, Florencio; Urdaneta, Elena; Ciencias del Medio Natural; Natura Ingurunearen Zientziak
    Research on cancer and other conditions has shown flavonoids and sphingolipids to be food components capable of exerting chemoprotective action. Nevertheless, little is known about their effects on healthy individuals and their potential usefulness as therapeutic agents. The present study examined the possible action of a dietary flavonoid, quercetin, and a sphingolipid, sphingomyelin, as functional foods in healthy animals. In particular, the effect on animal growth of supplementing a conventional diet with one or other of these substances (0·5% quercetin and 0·05% sphingomyelin) was considered. Possible action affecting intestinal physiology was also analysed by measuring the uptake of sugar and dipeptide, mediated by the Na+-dependent sugar transporter SGLT1 and the dipeptide Na+/H+ exchanger PEPT1 respectively, and the activity of related intestinal enzymes such as sucrase, maltase and aminopeptidase N. Both substances seemed to modify small intestinal activity in healthy mice, altering intestinal enzymatic activity and nutrient uptake. These effects observed in the small intestine did not impair normal development of the animals, as no differences in serum biochemical parameters or in organ and body weights were found. The findings should help in elucidating the mechanisms of action of these food components with a view to their possible use in the prevention of certain pathological conditions.
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    PublicationOpen Access
    Effect of insulin-like growth factor-I on nitrogen balance and intestinal galactose transport in rats with moderate liver cirrhosis
    (Cambridge University Press, 2003) Núñez, Marina; Urdaneta, Elena; Santidrián, Santiago; Ciencias del Medio Natural; Natura Ingurunearen Zientziak
    The malnutrition caused by liver cirrhosis (LC) often worsens the course of the disease. Patients affected by LC often have a low bioavailability of the anabolic liver peptide insulin-like growth factor (IGF)-I. The present study was undertaken to investigate the effect of low doses of IGF-I on the nutritional status and in vivo jejunal transport of d-galactose in anatomically, pathologically and biochemically confirmed moderate, non-ascitic, cirrhotic rats. LC was experimentally induced in growing rats by inhalation of CCl4 and addition of phenobarbital to drinking water. Both the nutritional status, as evaluated by N balance, and in vivo intestinal transport of d-galactose, were significantly impaired in cirrhotic rats. As compared with healthy rats, administration of 20μg human recombinant IGF-I/kg body weight for 14d to cirrhotic rats significantly improved N balance variables and restored in vivo intestinal transport of the sugar. However, IGF-I had no effect on the steatorrhoea associated with LC. These results suggest that low doses of IGF-I may have beneficial effects on the malnutrition associated with moderate LC.
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    Local (gut) and systemic metabolism of rats is altered by consumption of raw bean (Phaseolus vulgaris L. var. athropurpurea)
    (Cambridge University Press, 2003) Cavallé de Moya, Carmen; Grant, George; Frühbeck, Gema; Urdaneta, Elena; García, María; Marzo Pérez, Florencio; Santidrián, Santiago; Ciencias del Medio Natural; Natura Ingurunearen Zientziak
    The composition of the raw legume Phaseolus vulgaris L. var. athropurpurea (PhVa) and its effects on the metabolism of young growing rats have been evaluated. The levels of protein, unsaturated fatty acids, carbohydrate, fibre and bioactive factors present in PhVa were comparable with those in other Phaseolus vulgaris varieties. However, the lectins of PhVa were predominantly of the leucoagglutinating type, and concentrated in the albumin protein fraction. Rats fed a diet (110 g total protein, 16·0 M/g) in which PhVa meal provided about half of the protein excreted high levels of N in faeces and urine, and grew more slowly, than rats fed a high-quality control diet (ad libitum or pair-fed). Small intestine, large intestine and pancreas weights were increased (by almost 100 %, P<0·05), whilst skeletal muscle, thymus and spleen weights were reduced. Blood insulin 16·20 v. 0·50 m/, P<0·05, thyroxine, glucose, protein (60·5 v. 48·3 /, P<0·05) and LDL-cholesterol were lowered, whilst glucagon (155·3 v. 185·4 n/, P<0·05), triiodothyronine and urea were elevated, as were urinary urea, creatinine and glucose. These changes in the local (gut) and systemic metabolism of rats were probably mediated primarily by lectins in PhVa, which were concentrated in the albumin protein fraction, whereas in many other Phaseolus vulgaris lines they are distributed across the globulin and albumin fractions.
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    PublicationOpen Access
    Nutritional value of protein from vegetative mycelia of edible mushroom Pleurotus ostreatus
    (Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, 2006) Parada Albarracín, Julián Andrés; Urdaneta, Elena; Marzo Pérez, Florencio; Ramírez Nasto, Lucía; Pisabarro de Lucas, Gerardo; Producción Agraria; Nekazaritza Ekoizpena; Ciencias del Medio Natural; Natura Ingurunearen Zientziak
    The present work was designed to study the effects of supplementation a control diet with P. ostreatus mycelium for evaluation a nutritional value of mycoprotein and possible cholesterol lowering.