Dpto. Producción Agraria - Nekazaritza Ekoizpena Saila
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Browsing Dpto. Producción Agraria - Nekazaritza Ekoizpena Saila by Subject "Adipocytes"
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Publication Open Access Lipid metabolism, adipocyte depot physiology and utilization of meat animals as experimental models for metabolic research(Ivyspring International Publisher, 2010) Dodson, Michael V.; Hausman, Gary J.; Guan, LeLuo; Du, Min; Rasmussen, Theodore P.; Poulos, Sylvia P.; Mir, Priya; Bergen, Werner G.; Fernyhough, Melinda E.; McFarland, Douglas C.; Rhoads, Robert P.; Soret Lafraya, Beatriz; Reecy, James M.; Velleman, Sandra G.; Jiang, Zhihua; Producción Agraria; Nekazaritza EkoizpenaMeat animals are unique as experimental models for both lipid metabolism and adipocyte studies because of their direct economic value for animal production. This paper discusses the principles that regulate adipogenesis in major meat animals (beef cattle, dairy cattle, and pigs), the definition of adipose depot-specific regulation of lipid metabolism or adipogenesis, and introduces the potential value of these animals as models for metabolic research including mammary biology and the ontogeny of fatty livers.Publication Open Access Size and number variation of adipocytes during the growth of Rasa Aragonesa lambs(CIHEAM, 1995) Purroy Unanua, Antonio; Mendizábal Aizpuru, José Antonio; Soret Lafraya, Beatriz; Horcada, Alberto; Lizaso, G.; Mendizábal Múgica, Francisco Javier; Arana Navarro, Ana; Producción Agraria; Nekazaritza EkoizpenaThe size and number of adipocytes of different fat depots was studied in 45 male lambs of the Rasa Aragonesa breed, distributed in three groups of 15 lambs (G12, G24, G36), slaughtered respectively at 11.7 ± 0.67,24.5 ± 0.57 and 35.8 ± 1.74 kg live weight (LW) and at an age of 32 ± 5, 89 ± 8 and 123 ± 8 days. G12 lambs were slaughtered on the day of weaning, G24 and G36 lambs were weaned respectively at 16.2 ± 1.32 and 18.3 ± 2.46 kg LW and were fed from then onwards on concentrated fodder and barley straw ad libitum until they were slaughtered. The results obtained show that there is a significant increase in the amount of fat deposited in three internal (omental, mesenteric and kidney knob and channel) fat depots as the LW at slaughter increases (P<0.01). A similar phenomenon occurs in the size of the adipocytes, hypertrophy being more evident between 24 and 36 kg (P<0.01) than between 12 and 24 kg, except in the intermuscular fat depot, where the differences were between the two most extreme weight(P <0.01). The number of adipocytes in the omental and mesenteric fat depots increased significantly during the period of the study (P<0.01) while no variation occurred in the kidney knob and channel fat depot during the same period.Publication Open Access Skeletal muscle stem cells from animals I. basic cell biology(Ivyspring International Publisher, 2010) Dodson, Michael V.; Hausman, Gary J.; Guan, LeLuo; Du, Min; Rasmussen, Theodore P.; Poulos, Sylvia P.; Mir, Priya; Bergen, Werner G.; Fernyhough, Melinda E.; McFarland, Douglas C.; Rhoads, Robert P.; Soret Lafraya, Beatriz; Reecy, James M.; Velleman, Sandra G.; Jiang, Zhihua; Producción Agraria; Nekazaritza EkoizpenaSkeletal muscle stem cells from food-producing animals are of interest to agricultural life scientists seeking to develop a better understanding of the molecular regulation of lean tissue (skeletal muscle protein hypertrophy) and intramuscular fat (marbling) development. Enhanced understanding of muscle stem cell biology and function is essential for developing technologies and strategies to augment the metabolic efficiency and muscle hypertrophy of growing animals potentially leading to greater efficiency and reduced environmental impacts of animal production, while concomitantly improving product uniformity and consumer acceptance and enjoyment of muscle foods.Publication Open Access Variación de la actividad lipogénica en cabras de raza Blanca Celtibérica según su estado corporal(Sociedad Española de Ovinotecnia y Caprinotecnia, 2001) Mendizábal Aizpuru, José Antonio; Delfa, R.; Eguinoa Ancho, Paola; Arana Navarro, Ana; González, C.; Alzón, M.; Purroy Unanua, Antonio; Producción Agraria; Nekazaritza EkoizpenaEn 22 cabras adultas, secas y vacías, de raza Blanca Celtibérica con notas de condición corporal esternal comprendidas entre 1,5 y 4,5, se ha estudiado la variación de la cantidad de grasa, del tamaño y número de adipocitos, y de la actividad de las enzimas lipogénicas Glicerol 3P deshidrogenasa (G3PDH) y Sintetasa de ácidos grasos (FAS) en los depósitos grasos omental (OM), mesentérico (MES), pelvicorrenal (PVR), subcutáneo (SC) e intermuscular (IM) con la nota de condición corporal. Los resultados obtenidos muestran que el depósito graso SC es el que sufre un proceso de acumulación-movilización más intenso, seguido del OM, PVR, MES e IM, en este orden. El tamaño de los adipocitos varió en el mismo sentido que la cantidad de grasa, no observándose, en general, modificaciones en el número de adipocitos al variar la nota de condición corporal. Por último, la actividad de las enzimas G3PDH y FAS no se vió influenciada por la nCC.