Person:
Rodríguez Lorenzana, Alberto

person.page.identifierURI

https://academica-e.unavarra.es/handle/2454/49876

Last Name

Rodríguez Lorenzana

First Name

Alberto

person.page.departamento

Ciencias de la Salud

ORCID

0000-0003-0394-9230

person.page.upna

812901

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Now showing 1 - 10 of 15

Open Access
Multivariate base rates of low scores on tests of learning and memory among Spanish speaking children
(Taylor & Francis, 2020) Benito Sánchez, Itziar; Ertl, Melissa M.; Ferrer Cascales, Rosario; Oltra Cucarella, Javier; Ibáñez Alfonso, Joaquín A.; Saracostti Schwartzman, Mahia; Soto Añari, Marcio; Cadavid Ruiz, Natalia; Rodríguez Lorenzana, Alberto; Rivera, Diego; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun Zientziak
To determine the prevalence of low scores on two neuropsychological tests commonly used to evaluate learning and memory in children. 6,030 healthy children from 10 countries in Latin America and Spain were administered Rey–Osterrieth Complex Figure (ROCF) and the Test de Aprendizaje y Memoria Verbal–Infantil (TAMV-I). Results showed that low scores are common when multiple neuropsychological outcomes (tests and/or scores) are evaluated in healthy individuals. Clinicians should consider the higher probability of low scores in a given individual when evaluating learning and memory using various sets of scores to reduce false-positive diagnoses of cognitive deficits in pediatric populations.
Open Access
Normative data of neuropsychological tests of attention and executive functions in Ecuadorian adult population
(Routledge, 2021) Rodríguez Lorenzana, Alberto; Ramos Usuga, Daniela; Adana Díaz, Lila; Mascialino, Guido; Rivera, Diego; Ciencias de la Salud; Osasun Zientziak
Objective: The purpose of this study was to generate normative data for five tests of attention and executive functions (M-WCST, Stroop test, TMT, BTA, and SDMT), in a group of 322 Ecuadorian adults from Quito between the ages of 18 and 85. Method: Multiple regression analyzes taking into account age, education, and gender were used to generate the normative data. Results: Age and education were significantly related to test performance such that scores decreased with age and improved as a function of education. An online calculator is provided to generate normative test scores. Conclusions: This is the first study that presents normative data for tests of executive functions and attention in an Ecuadorian adult population. This data will improve the clinical practice of neuropsychology and help to develop the field in the country.
Open Access
Anxiety and depression in patients with confirmed and suspected COVID-19 in Ecuador
(Wiley, 2020) Paz, Clara; Mascialino, Guido; Adana Díaz, Lila; Rodríguez Lorenzana, Alberto; Simbaña-Rivera, Katherine; Gómez-Barreno, Lenin; Troya, Maritza; Páez, María Ignacia; Cárdenas, Javier; Gerstner, Rebekka M.; Ortiz-Prado, Esteban; Ciencias de la Salud; Osasun Zientziak
The rapid spread of the novel coronavirus, SARS-CoV-2 throughout the world has forced local and national administrations to take unprecedented measures to reduce the impact of the coronavirus diseases (COVID-19) pandemic. In South America, the arrival of the virus took longer than in other regions of the world, nevertheless, the impact has already been unprecedent. For instance, Ecuador was one of the most affected countries by the pandemic, reported hundreds of deaths each day during the last weeks of March and the first weeks of April 2020. The mortality rates were high during these months due to late implementation of restrictive measures of social distancing and limited capacity of health services (testing capacities and contact tracing). In this scenario, the Ecuadorian Ministry of Public Health (MoPH) established an epidemiological surveillance program for COVID-19 confirmed and suspected patients. The Department of Mental Health at the MoPH in Ecuador lead an active surveillance of the emotional impact of the disease by deploying an online self-reporting tool among patients to identify needs and provide standard of care treatment. The authors of this study were asked to participate in the development of this survey. The tool recorded sociodemographic variables and responses from two questionnaires: the Patient Health Questionnaire (PHQ-9) to measure the presence and severity of depressive symptoms, and the Generalized Anxiety Disorder (GAD-7) to assess the presence and severity of anxiety symptoms.
Open Access
Normative data for test of learning and memory in an Ecuadorian adult population
(Routledge, 2020) Rodríguez Lorenzana, Alberto; Nuñez Fernández, Silvia; Adana Díaz, Lila; Mascialino, Guido; Rivera, Diego; Ciencias de la Salud; Osasun Zientziak
Objective: The objective of this study was to develop norms for two neuropsychological tests of learning and memory in an Ecuadorian adult population. Method: 322 healthy individuals, ages between 18 and 84, were enrolled in the Metropolitan District of Quito. Participants were administered a comprehensive neuropsychological evaluation that included tests of learning and memory (Rey-Osterrieth Complex Figure Test [ROCF] and Hopkins Verbal Learning Test-Revised [HVLT-R]). Backward stepwise multiple linear regression analyses were used to examine the influence of demographic variables age, education, and gender on test performance. Normative data were developed adjusting for demographic variables found to be significant in the final regression models. Results: The final multiple linear models revealed performance on tests of learning and memory worsened with age and improved as a function of education. A user-friendly Excel-based calculator is presented to calculate the z score and percentile automatically based on raw score and sociodemographic information. Conclusion: This is the first study that presents normative data for tests of learning and memory for an adult population in Ecuador. It is expected that these norms will help to improve the clinical practice of neuropsychology in Ecuador by limiting erroneous raw score interpretation and incrementing diagnostic accuracy.
Embargo
Theory of planned behavior and alcohol use in adolescents in Ecuador: structural linear regression analysis
(Elsevier, 2024-02-13) Moreta-Herrera, Rodrigo; Córdova-Sánchez, Sheyla; Jaramillo-Zambrano, Ana ; Paredes-Proaño, Ana ; Mascialino, Guido; Rojas-Jara, Claudio ; Rodríguez Lorenzana, Alberto; Ciencias de la Salud; Osasun Zientziak
The general aim is to identify the explanatory potential of alcohol use intentions in drinking behaviors in a sample of adolescents in Ecuador. The method consists of a descriptive, explanatory, and cross-sectional study using SEM techniques. The participants were 384 adolescents (57% male and 43% female), aged 14–18 years (M = 16.51; SD = 2.64), who are students attending between the 1st and 3rd year of high school in a public educational institution in Ambato, Ecuador. Like principal results, the presence of alcohol use intention is moderate; the practice of alcohol use is low and mostly does not represent a risk, although 3.9% of the participants could report significant problems with consumption. Intentionality and drinking covary positively with low and moderate intensity. Drinking Intentionality explained 15.3% of the variance of drinking. We conclude that the Alcohol Use Intentions are a predictor of adolescent drinking behaviors.
Open Access
Validation of the Purpose in Life Scale-Short Form in an ecuadorian sample: factor analysis, reliability and graded response model
(UCOPress, 2023) Moreta-Herrera, Rodrigo; Rodríguez Lorenzana, Alberto; Mascialino, Guido; Caycho-Rodríguez, Tomás; López-Calle, Claudio; Gallegos, Miguel; Cervigni, Mauricio; Martino, Pablo; Vilca, Lindsey W.; Ciencias de la Salud; Osasun Zientziak
Introducción: El propósito de vida se analiza dentro del bienestar psicológico, se trata del sentido de vida que tienen las personas, lo que tiene implicaciones en áreas como la salud mental. Actualmente se requiere instrumentación precisa para su valoración de la población ecuatoriana, la cual por el momento es limitada. Objetivo: corroborar la estructura unidimensional de la Escala de Propósito en la Vida-Versión Corta (PIL-SF), la equivalencia de medida según género, la confiabilidad y los parámetros de discriminación y dificultad en una muestra de adultos ecuatorianos. Métodos: Estudio instrumental del PIL-SF bajo los preceptos de la Teoría Clásica de Test y la Teoría de Respuesta al Ítem. Participantes: 743 adultos ecuatorianos (64.2% mujeres y 45.8% hombres) de 18 a 73 años (M = 24.7, DT = 7.9). Resultados: Se confirmó la estructura unifactorial del PIL-SF con ajuste adecuado. Además, el PIL-SF es invariante a nivel fuerte en función del género y no se presentan diferencias a nivel de medias latentes. La confiabilidad de la consistencia interna es aceptable por grupo y los parámetros de discriminación y dificultad de los ítems son adecuados. Conclusión: El PIL-SF es una herramienta válida, confiable y precisa para medir el constructo Propósito en la Vida en adultos ecuatorianos.
Open Access
Nivel educativo y la autonomía funcional en adultos que residen en Quito (Ecuador)
(Fundación Universitaria Konrad Lorenz, 2019) Adana Díaz, Lila; Cuadros-López, Alejandra; Andrango-Guerrón, Dilan; Rodríguez Lorenzana, Alberto; Yacelga Ponce, Tarquino; Loureiro, Clara; Ciencias de la Salud; Osasun Zientziak
La incapacidad funcional del adulto asociada al envejecimiento poblacional genera un problema de salud pública. El objetivo de este artículo es estudiar la asociación existente entre el nivel educativo y la autonomía funcional de los adultos del Distrito Metropolitano de Quito (DMQ) en Ecuador. Para ello se realizó un análisis secundario con la información de la base de datos del estudio “Montreal Cognitive Assessment (MoCA): datos normativos para la población ecuatoriana”, que tiene un diseño transversal con adultos de 45 a 85 años. Se utilizó un modelo multivariado de regresión logística. El tamaño muestral fue de 328 participantes, de los cuales 301 fueron incluidos. Los resultados muestran diferencias significativas en cuanto al nivel educativo y la autonomía funcional: primero, permiten observar que un nivel educativo igual o mayor a los 12 años de instrucción es un factor de prevención de la pérdida de la autonomía funcional; segundo, muestran que hay una mayor posibilidad de pérdida de autonomía en función de la edad. Esta asociación existente entre el nivel educativo y la preservación de la autonomía funcional en el adulto en el DMQ muestra la importancia de promover el acceso a prácticas educativas permanentes en la población como parte de un programa de prevención de la pérdida de la autonomía mencionada.
Open Access
Behavioral and sociodemographic predictors of anxiety and depression in patients under epidemiological surveillance for COVID-19 in Ecuador
(Public Library of Science, 2020) Paz, Clara; Mascialino, Guido; Adana Díaz, Lila; Rodríguez Lorenzana, Alberto; Simbaña-Rivera, Katherine; Gómez-Barreno, Lenin; Troya, Maritza; Páez, María Ignacia; Cárdenas, Javier; Gerstner, Rebekka M.; Ortiz-Prado, Esteban; Ciencias de la Salud; Osasun Zientziak
Ecuador has been one of the most affected countries by the Corona Virus Disease 19 (COVID-19) pandemic, by April 2020 this country presented the highest rates of mortality in Latin America. The purpose of the present study was to identify behaviors during confinement and sociodemographic variables associated with the mental health status of confirmed or suspected COVID-19 patients who were part of the epidemiological surveillance program in Ecuador that included mandatory confinement and self-isolation. A cross-sectional study was performed from March 22th to April 18th, 2020 using an online survey. The survey collected socio-demographic information and severity of depressive symptoms using the Patient Health Questionnaire-9 and anxiety symptoms through the Generalized Anxiety Disorder-7. A total of 759 patients completed the questionnaire, 20.3% presented moderate to severe symptoms of depression and 22.5% moderate to severe symptoms of anxiety. Being a woman and from the Coastal region were risk factors. Exercising, maintaining daily routines, and keeping informed about the COVID-19 but limiting to an hour was associated with better mental health. Regression analysis indicated that the mentioned behaviors explained approximately 17% of the variance for depression sum scores and 11.8% of the variance for anxiety sum scores while controlling for gender and region. Understanding the association between sociodemographic variables and psychological states in patients with COVID-19 is relevant to tackle future public mental health problems and to implement health policies that are intended to palliate further psychiatric complications. Promotion of modifiable behaviors such as exercising, maintaining daily routines, and keeping informed about the COVID-19 but limiting to less than an hour is recommended.
Open Access
Relationship between subclinical psychotic symptoms and cognitive performance in the general population
(Elsevier, 2016) Martín-Santiago, Oscar; Suazo, Vanessa; Rodríguez Lorenzana, Alberto; Ruiz de Azúa, Sonia; Valcárcel, César; Díez, Álvaro; Grau, Adriana; Domínguez, Cristina; Gallardo, Ricardo; Molina, Vicente; Ciencias de la Salud; Osasun Zientziak
Introducción: En la población general, los síntomas psicóticos subclínicos se han asociado con mayores dificultades funcionales en la vida real, pero desconocemos si estos síntomas están asociados a un peor rendimiento cognitivo. El estudio de la relación entre las alteraciones cognitivas y estos síntomas puede, además, ayudarnos a comprender mejor las dificultades que presentan los pacientes con psicosis, en los que estas alteraciones cognitivas están presentes. Métodos: Realizamos evaluaciones clínicas y cognitivas en 203 sujetos de la población general mediante los instrumentos Community Assessment of Psychic Experiences, Brief Assessment of Cognition in Schizophrenia, Wechsler Adult Intelligence Scale y Wisconsin Card Sorting Test. Se evaluó la relación de los síntomas psicóticos subclínicos positivos y negativos con la edad y el rendimiento cognitivo. Además, se evaluó la influencia de los síntomas depresivos subclínicos sobre la posible relación entre síntomas positivos y negativos subclínicos y las alteraciones cognitivas. Resultados: Encontramos una relación inversa del rendimiento en la prueba de velocidad motora tanto con la frecuencia de síntomas positivos como con el distrés y la frecuencia de los síntomas negativos. También encontramos una relación directa entre el distrés de los síntomas positivos y el rendimiento en función ejecutiva. La puntuación en síntomas depresivos subclínicos se asoció con ambas escalas subclínicas, positiva y negativa. Conclusiones: Los síntomas psicóticos subclínicos están relacionados con déficits cognitivos en la población general, similares a los observados en poblaciones clínicas.
Open Access
Subchronic use of rivastigmine increases procognitive flexibility across multimodal behavioral tasks in healthy male rats
(Elsevier, 2019) Hormigo, Sebastian; Rodríguez Lorenzana, Alberto; Castro-Salazar, E.; Millian Morell, Lymarie; López, Dolores E.; Ciencias de la Salud; Osasun Zientziak
Rivastigmine (RVT) is a reversible inhibitor of cholinesterase approved worldwide for the treatment of cognitive dysfunctions, especially in Alzheimer's disease. Most previous pre-clinical studies have examined the effects of RVT treatment in a wide variety of pathological research models. Nonetheless, the effects of this drug on sensorimotor gating, memory, and learning tasks in healthy subjects remains unclear. In this study, we investigate the procognitive effects of RVT treatment in healthy rats through sensorimotor gating evaluations (measured as prepulse inhibition of the acoustic startle reflex), active avoidance learning, and spatial memory learning in a radial maze. There is an increase in the amplitude of the startle reflex in RVT-treated rats compared to the control groups, whereas the latency remained constant. Sensorimotor gating values were also incremented compared to those values from controls. In active avoidance, rats treated with RVT learned faster to successfully perform the task compared to controls, but afterwards all groups exhibited virtually identical results. During the sessions in the radial maze, RVT-treated rats committed fewer errors in both the working and reference memory compared to controls. All in all, our results support the hypothesis that RVT treatment may entail procognitive effects in healthy subjects.