Person: Rivera, Diego
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Rivera
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Diego
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Ciencias de la Salud
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0000-0001-7477-1893
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811845
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Publication Open Access 15-item version of the Boston naming test: normative data for the Latin American spanish-speaking adult population.(American Psychological Association, 2023) Cacho Tena, Ana María del; Merced, Kritzia; Perrin, Paul B.; Arango Lasprilla, Juan Carlos; Olabarrieta Landa, Laiene; Rivera, Diego; Ciencias de la Salud; Osasun ZientziakObjective: Naming is commonly impaired in people with neurodegenerative diseases and brain injury, and as a result, its accurate assessment is essential. The aim of this study was to provide normative data for the 15-item Spanish version of the Boston Naming Test (BNT) for an adult population from eight Latin American countries/regions. Method: The total sample consisted of 2,828 participants from Argentina, Chile, Cuba, El Salvador, Mexico, Honduras, Paraguay, and Puerto Rico. Multiple regressions were used to generate normative data following a four-step process. Results: Regression models showed a linear effect of age on the 15-item BNT total score for Argentina, Chile, Mexico, and Puerto Rico. In contrast, Paraguay showed a quadratic age effect. Almost all countries showed a positive linear effect of education, except Cuba which had a quadratic effect. Sex was a significant predictor in Argentina, Chile, Cuba, and Mexico, where in women scored lower than men. Conclusions: This study generates normative data for the 15-item Spanish version of the BNT and offers a free open-source calculator that will assist in the efficacious use of this neuropsychological test in clinical practice and research.Publication Open Access Validation of the Norma Latina neuropsychological assessment battery in patients with Alzheimer's disease in Mexico(MDPI, 2022) Nuñez Fernández, Silvia; Rivera, Diego; Arroyo-Anlló, Eva María; Ortiz Jiménez, Xóchitl Angélica; Camino-Pontes, Borja; Salinas Martínez, Ricardo; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakTo our knowledge, this is the first study reported in the literature that has validated the Norma Latina Battery in a population of people with Alzheimer’s disease (AD) in Mexico. The objective of the study was to determine the discriminant validity of the Norma Latina Battery in a group of Mexican individuals with AD and a group of heathy controls (HC). The Norma Latina Battery was administered to 234 Mexican participants (117 HC and 117 individuals with AD). Results show that: (1) the Norma Latina Battery has high discriminative capacity between groups in all domains; (2) participants with AD presented worse scores in each of the cognitive domains compared to the HC and a greater number of low scores in each of the established thresholds or cut-off points; and finally, (3) the Norma Latina Battery had optimal sensitivity and specificity, especially when a set was observed ≥5 scores below the 10th percentile or ≥4 scores below the 5th percentile. In conclusion, it is recommended that both clinicians and researchers use this battery in the evaluation of Mexican people with AD to better understand the prognosis of the disease and its subsequent treatment.Publication Open Access The Family Needs Questionnaire-Revised: a Rasch analysis of measurement properties in the chronic phase after traumatic brain injury(Taylor & Francis, 2020) Røe, Cecilie; Anke, Audny; Arango Lasprilla, Juan Carlos; Andelic, Nada; Rivera, Diego; Ciencias de la Salud; Osasun ZientziakPurpose: The main aim was to evaluate the measurement properties of the Family Needs Questionnaire-Revised (FNQ-R) in family members of individuals living with severe traumatic brain injury (TBI). Methods: A total of 309 family members of individuals with severe TBI from Colombia, Denmark, Mexico, Norway and Spain participated. Rasch analysis of the FNQ-R and its 6 subscales was conducted. Results: The Rasch analysis indicated a lack of fit of the 37-item FNQ-R to one single underlying construct of needs, and less than half of the items were invariant across the countries. Misfit of single items was revealed in the Need for Health Information, Need for Emotional Support, Need for Instrumental Support, Need for Professional Support and Need for Community Support Network subscales. Fit to the Rasch model was obtained after removal of misfitting items. The Involvement in Care subscale had too few items to be adequately assessed by the Rasch approach. Conclusion: The FNQ-R is a well-targeted instrument for assessing the unmet needs of caregivers regarding the need for health information, emotional support, professional support and a community support network after some scoring adjustment and the removal of misfitting items. Caution should be taken when comparing responses across countries.Publication Open Access Multivariate base rates of low scores on tests of learning and memory among Spanish speaking children(Taylor & Francis, 2020) Benito Sánchez, Itziar; Ertl, Melissa M.; Ferrer Cascales, Rosario; Oltra Cucarella, Javier; Ibáñez Alfonso, Joaquín A.; Saracostti Schwartzman, Mahia; Soto Añari, Marcio; Cadavid Ruiz, Natalia; Rodríguez Lorenzana, Alberto; Rivera, Diego; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakTo determine the prevalence of low scores on two neuropsychological tests commonly used to evaluate learning and memory in children. 6,030 healthy children from 10 countries in Latin America and Spain were administered Rey–Osterrieth Complex Figure (ROCF) and the Test de Aprendizaje y Memoria Verbal–Infantil (TAMV-I). Results showed that low scores are common when multiple neuropsychological outcomes (tests and/or scores) are evaluated in healthy individuals. Clinicians should consider the higher probability of low scores in a given individual when evaluating learning and memory using various sets of scores to reduce false-positive diagnoses of cognitive deficits in pediatric populations.Publication Open Access Prevalence of low scores on executive functions tests in a Spanish-speaking pediatric population from 10 Latin American countries and Spain(Taylor & Francis, 2020) Benito Sánchez, Itziar; González, Isabel; Oliveras Rentas, Rafael E.; Ferrer Cascales, Rosario; Romero García, Ivonne; Restrepo Botero, Juan Carlos; Delgado Mejía, Iván Darío; Vergara Moragues, Esperanza; Rivera, Diego; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakPediatric neuropsychologists and researchers commonly interpret a low score as a cognitive weakness. The purpose of the study was to determine the prevalence of low scores for three neuropsychological tests used to evaluate executive function in 4,595 healthy children from Latin-America and Spain. Results showed that low scores are common when multiple neuropsychological outcomes are evaluated in healthy individuals. Clinicians should consider the higher probability of low scores in a given individual when evaluating executive functions using various sets of scores to reduce false-positive diagnoses of cognitive deficits in a child.Publication Open Access Comparability of (post-concussion) symptoms across time in individuals after traumatic brain injury: results from the CENTER-TBI study(MDPI, 2022) Rivera, Diego; Greving, Sven; Arango Lasprilla, Juan Carlos; Von Steinbuechel, Nicole; Zeldovich, Marina; Ciencias de la Salud; Osasun ZientziakPost-concussion symptoms often occur after TBI, persist and cause disabilities. The Rivermead Post-Concussion Symptoms Questionnaire (RPQ) is widely used in this population, but little is known about the comparability of the symptoms over time, i.e., longitudinal measurement invariance (MI). The objectives of this study were to analyze the longitudinal MI of RPQ symptoms from three to twelve months after TBI and to find factors related to RPQ symptoms. The study involved 1023 individuals after TBI who took part in the Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI) study and completed the RPQ at three, six and twelve months postinjury. Longitudinal confirmatory factor analysis showed that the three-factor structure (somatic, emotional and cognitive) remains stable within one year after TBI. Linear mixed models revealed that sex, injury cause and prior psychiatric problems were related to the RPQ three-factor structure as well as to the RPQ total score. The study strengthens evidence for the RPQ’s factorial structure stability within one year after TBI and identifies sex, injury cause and prior psychiatric problems as important factors that may help clinicians to prevent future complications of symptomatology after TBI.Publication Open Access Validation of the Norma Latina neuropsychological assessment battery in individuals with multiple sclerosis in Mexico(Elsevier, 2022) Rivera, Diego; Ramos Usuga, Daniela; Fuentes Mendoza, Eliana María; Aguayo Arelis, Adriana; Rabago Barajas, Brenda Viridiana; Macías Islas, Miguel Ángel; Krch, Denise; Lequerica, Anthony H.; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakBackground. Between 50-60% of Multiple Sclerosis (MS) patients have cognitive alterations. There are several batteries to assess cognitive impairments in MS, however, few exist for Latin Americans. The objective of this study is to evaluate the neuropsychological profile of Mexican people with MS (PwMS) and assess the utility of Norma Latina, a new battery for cognitive assessment in Latin America, in differentiating cognitive test performance between PwMS and healthy controls (HC). Methods. 100 PwMS and 100 HC from Mexico were evaluated with the Norma Latina battery. The following analyses were conducted: 1) low-percentiles of each participant were calculated, 2) Area Under the Curve was used to determine whether the battery discriminated between PwMS and HC, 3) four composite scores were calculated, and student’s t-test was used to compare groups according to these domains. Results. PwMS obtained a greater number of impaired scores compared to HCs, principally in executive function. The battery successfully discriminated between PwMS and HCs, with the strongest capacity to discriminate in the executive functions, and the weakest in memory. Conclusion. Establishing validation of a neuropsychological battery for Mexican PwMS will help to more accurately detect cognitive alterations, which will guide the decisions of professionals in terms of cognitive rehabilitation.Publication Open Access Multivariate base rates of low score on neuropsychological tests of individuals with coca paste use disorder(Oxford University Press, 2023) Vergara Moragues, Esperanza; Acosta Barreto, María Rocío; Rivera, Diego; Santiago Ramajo, Sandra; González-Saiz, Francisco; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakOBJECTIVE: The aim of this study was to determine the prevalence of low scores on eight commonly used neuropsychological tests to evaluate learning and memory, language, and executive functions in individuals with coca paste use disorders (CPUD) and to identify the differences with respect to a group of healthy nonconsuming subjects (HCs). METHODS: 162 Colombian adults with CPUD and a group of 162 Colombian adult HCs participated in this comparative study. Eight tests (eighteen test scores) were grouped into three categories: learning and memory, language, and executive functions. Each participant was categorized based on the number of low scoring tests in specific percentile cut-off groups (25th, 16th, 10th, 5th, and 2nd). RESULTS: In the learning and memory domain, 89.5% of individuals with CPUD and 55.6% of HCs scored below the 25th percentile on at least one of the five test scores, in the language domain, 80.7% of individuals with CPUD and 58% of HCs and in the executive function domain, 92% of individuals with CPUD and 67.3% of HCs. Having two or more scores below the 10th percentile or 10 or more at the 5th percentile shows an optimal cut-off for determining the sensitivity and specificity for discriminating between the two groups. CONCLUSIONS: The individuals with CPUD had a higher percentage of low scores than the HCs in the domains of learning and memory, language, and executive function. It is important for clinicians to be aware of low scores in individuals with CPUD to avoid false-positive diagnoses of cognitive impairment.Publication Open Access Multivariate base rates of low scores on tests of executive functions in a multi-country Latin American sample(Routledge, 2021) Rivera, Diego; Mascialino, Guido; Brooks, Brian L.; Olabarrieta Landa, Laiene; Longoni, Melina; Galarza-Del-Ángel, Javier; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun ZientziakThe objective of the study was to determine the prevalence of low scores in a diverse Latin American population for two neuropsychological commonly used tests to evaluate executive functions and to compare the number of low scores obtained using normative data from a Spanish-speaking population from Latin America versus an English-speaking population from U.S.A. Healthy adults (N = 5402) were administered the Modified Wisconsin Card Sorting Test and Stroop Color-Word. Low scores on measures of executive functioning are common. Clinicians working with Spanish-speaking adults should take into account the higher probability of low scores on these measures to reduce false-positive diagnoses of cognitive deficits in an individual.Publication Open Access Phonological and semantic verbal fluency test: Scoring criteria and normative data for clustering and switching strategies for Colombian children and adolescents(Wiley, 2023) Álvarez Medina, María Nazareth; Vergara Moragues, Esperanza; Arango Lasprilla, Juan Carlos; Restrepo Moreno, Juan Carlos; Calderón Chagualá, José Amilkar; Rivera, Diego; Olabarrieta Landa, Laiene; Ciencias de la Salud; Osasun Zientziak; Universidad Pública de Navarra / Nafarroako Unibertsitate PublikoaBackground: Verbal fluency tests (VFT) are highly sensitive to cognitive deficits. Usually, the score on VFT is based on the number of correct words produced, yet it alone gives little information regarding underlying test performance. The implementation of different strategies (cluster and switching) to perform effi-ciently during the tasks provide more valuable information. However, normative data for clustering and switching strategies are scarce. Moreover, scoring criteria adapted to Colombian Spanish are missing. Aims: (1) To describe the Colombian adaptation of the scoring system guidelines for clustering and switching strategies in VFT; (2) to determine its reliability; and (3) to provide normative data for Colombian children and adolescents aged 6–17 years. Methods & Procedures: A total of 691 children and adolescents from Colombia completed phonological (/f/, /a/, /s/, /m/, /r/ and /p/) and semantic (animals and fruits) VFT, and five scores were calculated: total score (TS), number of clusters (NC), cluster size (CS), mean cluster size (MCS) and number of switches (NS). The intraclass correlation coefficient was used for interrater reliability. Hierarhical multiple regressions were conducted to investigate which strategies were associated with VFT TS. Multiple regressions were conducted for each strategy, including as predictors age, age2, sex, mean parents’ education (MPE), MPE2 and type of school, to generate normative data. Outcomes & Results: Reliability indexes were excellent. Age was associated with VFT TS, but weakly compared with strategies. For both VFT TS, NS was the strongest variable, followed by CS and NC. Regarding norms, age was the strongest predictor for all measures, while age2 was relevant for NC (/f/phoneme) and NS (/m/ phoneme). Participants with higher MPE obtained more NC, and NS, and larger CS in several phonemes and categories. Children and adolescents from private school generated more NC, NS and larger CS in /s/phoneme. Conclusions & Implications: This study provides new scoring guidelines and normative data for clustering and switching strategies for Colombian children and adolescents between 6 and 17 years old. Clinical neuropsychologists should include these measures as part of their everyday practice.