Gómez Fernández, Germán Orlando
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Gómez Fernández
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Germán Orlando
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Publication Open Access Alliaceae-derived supplementation improves the severity of COVID-19 symptoms among elderly nursing home residents(MDPI, 2024) Vázquez-Blanquiño, Alberto; Pérez-Rodríguez, Lucía; Alberola-Romano, Ana; Martínez-Pérez, María; Baños, Alberto; Gómez Fernández, Germán Orlando; Gracián, Carlos; Fonollá, Juristo; García, Federico; Ciencias; ZientziakThis study investigates the effect of daily consumption of a concentrated garlic and onion extract on COVID-19 symptoms among elderly nursing home residents. Volunteers consumed a daily capsule of the concentrated powder rich in organosulfur compounds over 36 weeks during lunch. The incidence and severity of COVID-19 symptoms between the treatment and control groups were compared, along with monitoring the safety of consumption, incidence of other diseases, and medicine usage. The treatment group showed a significant reduction in both the number and severity of COVID-19 symptoms compared to the control group, with no significant adverse effects observed. No significant reduction in symptom duration was detected. This study provides preliminary evidence that concentrated garlic and onion extract may aid in the treatment of COVID-19 among older adults. These findings suggest potential public health benefits, emphasizing the need for further research to explore the immunomodulatory properties of these natural compounds.Publication Open Access LDL-cholesterol-lowering effects of a dietary supplement containing onion and garlic extract used in healthy volunteers(MDPI, 2024-08-22) Vezza, Teresa; Guillamón, Enrique; García-García, Jorge; Baños, Alberto; Mut-Salud, Nuria; García-López, José David; Gómez Fernández, Germán Orlando; Rodríguez-Nogales, Alba; Gálvez Peralta, Julio Juan; Fonollá, Juristo; Ciencias; ZientziakHypercholesterolemia plays a pivotal role in the development and progression of cardiovascular diseases, and its prevention seems to be a crucial healthcare strategy to ameliorate these conditions. Subjects with mild hypercholesterolemia are frequently advised against using cholesterol-lowering drugs due to potential side effects, with an emphasis instead on prioritizing dietary adjustments and lifestyle modifications as the primary strategy. In this context, the use of dietary supplements based on medicinal plants may be recommended as a complementary approach to managing elevated cholesterol levels. The aim of this study was to investigate the safety and potential therapeutic effectiveness of a standardized formulation containing extracts from garlic and onions in addressing the health concerns of individuals with slightly elevated cholesterol levels. A controlled, randomized, double-blind, two parallel-group study was conducted over 8 weeks, with clinical visits scheduled at baseline, weeks 2 and 4, as well as at the end of the study. The results revealed significant reductions in both low-density lipoprotein cholesterol and total cholesterol levels among participants who received the extract. Additionally, improvements in blood pressure, as well as in oxidative and inflammatory markers were observed, thus suggesting its potential as a valuable therapeutic intervention for managing mild hypercholesterolemia.