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López Sáez de Asteasu, Mikel

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https://academica-e.unavarra.es/handle/2454/49456

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López Sáez de Asteasu

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Mikel

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Ciencias de la Salud

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0000-0002-4111-5045

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810971

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2014 - 201912020 - 20212
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Subject: Muscle strength ×

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Now showing 1 - 3 of 3
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    PublicationOpen Access
    Handgrip strength as a moderator of the influence of age on olfactory impairment in US adult population ≥ 40 years of age
    (Nature Research, 2021) Ramírez Vélez, Robinson; López Gil, José Francisco; López Sáez de Asteasu, Mikel; Izquierdo Redín, Mikel; García Hermoso, Antonio; Ciencias de la Salud; Osasun Zientziak; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
    The aim of this study was to determine whether handgrip strength attenuates the negative relationship between age and olfactory function in a representative US population sample 40 years old and over. A cross-sectional study was performed with 2861 adults from the US National Health and Nutrition Examination Survey NHANES (2013–2014). An 8-item odor identification test was applied to determine olfactory function. Muscle strength was determined through a handgrip dynamometer (defined as the sum of the largest handgrip strength reading from right and left hands). Moderation analysis was performed to test whether the association between age and olfactory impairment was moderated by handgrip strength. Moderation analysis highlighted two regions of significance: the first region was found at < 56.6 kg, indicating that the adverse influence of age on olfactory function may be greater for the participants in this area; the second region was found at ≥ 56.6 kg, indicating that the negative impact of age on olfactory function disappeared for adults who were above this estimate point. In conclusion, handgrip strength, a general indicator of muscle strength, moderates the relationship between age and olfactory ability in a US adult population aged 40 years and older. Our findings are clinically relevant, since they emphasize the importance of muscular fitness in adulthood and old age by diminishing the deleterious effect of aging on olfactory performance.
  • Thumbnail Image
    PublicationOpen Access
    Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults: a moderation analysis
    (MDPI, 2020) Ramírez Vélez, Robinson; Pérez Sousa, Miguel A.; García Hermoso, Antonio; Zambom Ferraresi, Fabrício; Martínez Velilla, Nicolás; López Sáez de Asteasu, Mikel; Cano Gutiérrez, Carlos Alberto; Rincón Pabón, David; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
    The adverse effects of fat mass on functional dependence might be attenuated or worsened, depending on the level of muscular strength. The aim of this study was to determine (i) the detrimental effect of excess adiposity on dependence in activities of daily living (ADL), and (ii) whether relative handgrip strength (HGS) moderates the adverse effect of excess adiposity on dependence, and to provide the threshold of relative HGS from which the adverse effect could be improved or worsened. A total of 4169 participants (69.3 +/- 7.0 years old) from 244 municipalities were selected following a multistage area probability sampling design. Measurements included anthropometric/adiposity markers (weight, height, body mass index, waist circumference, and waist-to-height ratio (WHtR)), HGS, sarcopenia 'proxy' (calf circumference), and ADL (Barthel Index scale). Moderation analyses were performed to identify associations between the independent variable (WHtR) and outcomes (dependence), as well as to determine whether relative HGS moderates the relationship between excess adiposity and dependence. The present study demonstrated that (i) the adverse effect of having a higher WHtR level on dependence in ADL was moderated by relative HGS, and (ii) two moderation thresholds of relative HGS were estimated: 0.35, below which the adverse effect of WHtR levels on dependency is aggravated, and 0.62, above which the adverse effect of fat on dependency could be improved. Because muscular strength represents a critically important and modifiable predictor of ADL, and the increase in adiposity is inherent in aging, our results underscore the importance of an optimal level of relative HGS in the older adult population.
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    PublicationOpen Access
    Efectos del entrenamiento de fuerza en un programa comunitario en pacientes con enfermedad pulmonar obstructiva crónica
    (2014) López Sáez de Asteasu, Mikel; Antón Olóriz, María Milagros; Zambom Ferraresi, Fabrício; Escuela Universitaria de Estudios Sanitarios; Osasun Ikasketen Unibertsitate Eskola
    Introducción: Un programa mantenimiento supervisado mantiene los efectos beneficiosos en la fuerza máxima, potencia muscular, y tolerancia al ejercicio conseguidos después de un programa de rehabilitación. Objetivos: Examinar efectos de la inclusión de un programa de fuerza del miembro inferior (MMII) en un programa de mantenimiento en la fuerza máxima y la potencia muscular del MMII. Metodología: Sujetos (N=9) varones diagnosticados de enfermedad pulmonar obstructiva crónica (EPOC) moderado-severo según criterios de la GOLD fueron evaluados de fuerza máxima, potencia muscular del MMII con cargas submáximas, distancias test 6 minutos marcha (T6MM), y calidad de vida relacionada. Resultados: Fuerza máxima (p<0.05), potencia muscular con cargas submáximas (p≤0.05- 0.001), y la distancia T6MM (p<0.05) incrementó un 5%, 7-23% y 16 metros, respectivamente. No hubo cambios significativos en calidad de vida. Conclusiones: Inclusión de programa de fuerza de MMII en programa comunitario mejora la fuerza máxima, potencia muscular, y tolerancia al ejercicio