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Guillén Grima, Francisco

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Guillén Grima

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Francisco

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Ciencias de la Salud

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0000-0001-9749-8076

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352

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Now showing 1 - 10 of 46
  • PublicationOpen Access
    Prevalence and risk factors for wheezing in infants in the region of Pamplona, Spain
    (Elsevier, 2016) Álvarez Álvarez, Ismael; Niu, Hao; Aguinaga Ontoso, Inés; Guillén Grima, Francisco; Ciencias de la Salud; Osasun Zientziak; Gobierno de Navarra / Nafarroako Gobernua: 6106
    Background: Wheezing in the first year of life affects life’s quality of the baby and the family. Risk factors such as male gender, nursery attending or a family history of asthma, and protective factors such as breastfeeding more than 6 months have been previously described. The aim of this study is to study the prevalence and risk factors for wheezing ever and recurrent wheezing in the first year of life in infants in the region of Pamplona, Spain. Material and methods: This cross-sectional study was part of the International Study of Wheezing in Infants (Estudio Internacional de Sibilancias en Lactantes, EISL). Between 2006 and 2008, participating families answered a standardized validated questionnaire on respiratory symptoms, environmental factors or family issues. An analysis with the chi square test (statistical significance p<0.05) identified the risk factors for wheezing ever and recurrent wheezing, which were assessed using logistic regression. Results: 1065 questionnaires were answered. The prevalence of wheezing ever and recurrent wheezing were 31.2% and 12.3%, respectively. Male gender (p=<0.001), a history of pneumonia (p=<0.001) or nursery attendance (p=<0.001) were some of the risk factors found for wheezing ever. Infant eczema (p=<0.001), nursery attendance (p=<0.001) or prematurity (p=<0.001) were risk factors for recurrent wheezing. No associations with duration of breastfeeding (p=0.116 and p=0.851) or mould stains at home (p=0.153 and p=0.992) were found. Conclusion: The study of prevalence and risk factors for wheezing shows the importance of this public health problem, and allows the development of control and treatment strategies against preventable factors.
  • PublicationOpen Access
    Infant mortality in the European Union: a time trend analysis of the 1994-2015 period
    (Elsevier España, 2019) Onambele, Luc; San Martín Rodríguez, Leticia; Niu, Hao; Álvarez Álvarez, Ismael; Arnedo Pena, Alberto; Guillén Grima, Francisco; Aguinaga Ontoso, Inés; Ciencias de la Salud; Osasun Zientziak
    Introducción: La mortalidad infantil es un indicador de la salud infantil y una variable explicativa del desarrollo socioeconómico. Nuestro objetivo fue examinar los cambios y tendencias de la mortalidad infantil en la Unión Europea (UE) y sus 28 países miembros en el período 1994-2015. Métodos: Se recopilaron datos de muertes de niños menores de un año entre 1994 y 2015 de la base de datos Eurostat. Estudiamos las tendencias en la UE, por países y regiones, utilizando elanálisis de regresión joinpoint. Se condujeron análisis adicionales para estudiar las tendencias de mortalidad neonatal y neonatal precoz. Resultados: La mortalidad infantil en la UE ha disminuido significativamente de 8.3 a 3.6 por 1.000 (porcentaje de cambio anual = −3.8%, intervalos de confianza del 95% −4.1; −3.6). Las tasas de mortalidad más altas se registraron en Rumanía y Bulgaria, y las tasas más bajas en países escandinavos (Finlandia, Suecia). Se encontraron tendencias descendentes significativas en los países de la UE, más pronunciadas en los países bálticos exsoviéticos y países de Europa oriental, mientras que los países de Europa occidental mostraron los descensos menos pronunciados. La mortalidad infantil ha aumentado significativamente en Grecia en los últimos años,mientras que en el Reino Unido e Irlanda las tasas se han estabilizado. Conclusiones: La mortalidad infantil ha disminuido en la UE y sus países en las últimas décadas, más pronunciadamente en los países de Europa oriental y los países bálticos exsoviéticos, mientras que en varios países de Europa occidental las tasas aumentaron o se han estabilizado enlos últimos años.
  • PublicationOpen Access
    Student estimations of peer alcohol consumption: links between the Social Norms Approach and the Health Promoting University concept
    (SAGE, 2014) Stock, Christiane; McAlaney, John; Pischke, Claudia R.; Vriesacker, Bart; Guillén Grima, Francisco; Ciencias de la Salud; Osasun Zientziak
    Background: The Social Norms Approach, with its focus on positive behaviour and its consensus orientation, is a health promotion intervention of relevance to the context of a Health Promoting University. In particular, the approach could assist with addressing excessive alcohol consumption. Aim: This article aims to discuss the link between the Social Norms Approach and the Health Promoting University, and analyse estimations of peer alcohol consumption among European university students. Methods: A total of 4392 students from universities in six European countries and Turkey were asked to report their own typical alcohol consumption per day and to estimate the same for their peers of same sex. Students were classified as accurate or inaccurate estimators of peer alcohol consumption. Socio-demographic factors and personal alcohol consumption were examined as predictors for an accurate estimation. Results: 72% of male and 51% of female students were identified as having accurate estimations about the amount of alcoholic drinks consumed per day by their peers. Male students, older students, those studying year 3 and above, and Turkish and Danish students were more likely to accurately estimate their peers’ alcohol consumption. Independent from these factors, students’ accurate estimation of peers’ drinking decreased significantly with increasing personal consumption. Conclusions: As accurate estimates of peer alcohol consumption appear to affect personal drinking behaviour positively, Social Norms interventions targeted at correcting possible misperceptions about peer alcohol use among students may be a useful health promotion tool in the context of a Health Promoting University.
  • PublicationOpen Access
    Trends in hospital morbidity from Alzheimer's disease in the European Union, 2000-2014
    (SAGE, 2018) Niu, Hao; Álvarez Álvarez, Ismael; Aguinaga Ontoso, Inés; Guillén Grima, Francisco; Ciencias de la Salud; Osasun Zientziak
    Background: Alzheimer’s disease (AD) has become a concerning public health issue. We aimed to analyse the trends of hospital morbidity from AD in the European Union (EU) in the period 2000-2014. Methods: Data from hospital discharges of men and women over 50 years old hospitalised from AD in the EU were extracted from Eurostat database. We tested for secular trends computing the annual percent change, and identifying significant changes in the linear slope of the trend. Results: Hospital morbidity from AD showed a 0.8% (95% confidence intervals -2.2, 0.6) slight declining trend in the EU. In men and women, we recorded a -0.5% and -1.0% decrease in hospital morbidity rates, respectively. Several countries showed changing trends during the study period. Conclusion: AD hospital morbidity has slightly declined in the entire EU in the past years. Eastern European countries showed steadily increasing trends, whereas in western and Mediterranean countries rates decreased or levelled off.
  • PublicationOpen Access
    Factores de riesgo cardiovascular en universitarios de primer y tercer año
    (Sociedad Médica de Santiago, 2017) Morales Illanes, Gladys; Guillén Grima, Francisco; Muñoz Navarro, Sergio; Belmar, Carlos; Schifferli, Ingrid; Ciencias de la Salud; Osasun Zientziak
    Background: College students are in a critical stage in their life style due to the transition between high school and university and they may be prone to develop cardiovascular diseases. Aim: To compare the prevalence of cardiovascular risk factors (CVRF) in students from first and third year at the University of La Frontera, Temuco-Chile, according to faculty, gender and socioeconomic status (SES). Material and Methods: Cross-sectional study. Anthropometry, blood pressure, lipid profile, blood glucose, insulin resistance (IR), sedentary lifestyle, tobacco and alcohol consumption were evaluated during 2014 in randomly selected 163 freshmen aged 19.2 ± 1.8 years and 163 third year students aged 21.7 ± 2.5 years (49% females), stratified by faculty, career and gender. Results: 32.4% of students had prehypertension, 30.6% abdominal obesity, 26.3% insulin resistance, 25.7% dyslipidemia and 8.9% metabolic syndrome. Third grade students had higher prevalence of elevated total and LDL cholesterol and higher alcohol consumption, especially among students of middle and high socioeconomic level. Compared with students from the School of Medicine, students from the Education Faculty had 3.9, 3.3 and 2.7 times greater likelihood of being obese, having elevated LDLcholesterol and being smokers, respectively. Women had the highest prevalence of sedentary lifestyles and dyslipidemia. Men had the highest prevalence of prehypertension and smoking. Conclusions: Educational programs are required to promote healthy lifestyles among these students.
  • PublicationOpen Access
    Med-health: the Mediterranean health alliance
    (2016) Guillén Grima, Francisco; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
    Presentación del proyecto Med-health, de la acción K2, orientado a la formación de gestores de salud pública.
  • PublicationOpen Access
    Efectividad de la atención primaria de salud en el diagnóstico y tratamiento de la hipertensión arterial
    (Gobierno de Navarra, 2008) Brugos Larumbe, Antonio; Guillén Grima, Francisco; Díez, J.; Buil, P.; Ciaurriz, M.; Fernández Valdivielso, Carlos; Cenoz, J. C.; Ciencias de la Salud; Osasun Zientziak
    La hipertensión arterial (HTA) es un importante problema de salud pública, por su elevada morbimortalidad cardiovascular y sus costes económicos y sociales. Fundamento. Identificar la prevalencia de HTA detectada en atención primaria y su grado de control; conocer los tipos de tratamientos utilizados y factores asociados a su control. Pacientes y métodos. Estudio transversal comparativo de dos años en el Centro de Salud de Villava. Se analizan los datos de la historia clínica informatizada en los años 2003 y 2006. Se estudian las variables: edad, género, pensión arterial sistólica y diastólica, colesterol total, HDL, LDL, triglicéridos, tabaquismo, índice de masa corporal en ambos años. Tratamiento hipotensor en el año 2006. Mediante regresión logística se identifican las variables del año 2006 asociadas a buen control. Resultados. Prevalencia detectada de HTA en ≥18 años: 2003: 11,6% (IC:10,9-12,3); 2006: 16,6% (IC:15,8-17,4) (p<0,001). En hipertensos con registro de presión arterial estaban controlados (PA:<140/90) en 2003: 45,1% (IC: 41,0- 48,0) y en 2006: 40,4% (IC: 37,7-43,2) (p<0,05). Variables asociadas a buen control: ser varón [OR 1,60 (IC: 1,26-2,03)] tratamiento con ARA II [OR 2,16 (IC: 1,50-3,09)] y ser diabético [OR 1,50 (IC: 1,10-2,03]. Se asocian a mal control: presentar enfermedad vascular cerebral, vasculopatía periférica y el tratamiento con IECA. Conclusiones. La prevalencia de HTA detectada es baja. El nivel de control es superior para la PAD que para la PAS. El tratamiento con ARA II, ser varón o ser diabético se asocia a mejor control. La vasculopatía periférica, la cardiopatía isquémica, la enfermedad vascular cerebral, el tratamiento con IECA y edad se asocian a peor control.
  • PublicationOpen Access
    Validation study of a Spanish version of the modified Telephone Interview for Cognitive Status (STICS-m)
    (Elsevier, 2018) Muñoz-García, Mariana; Cervantes, Sebastián; Razquin, Cristina; Guillén Grima, Francisco; Toledo, Juan B.; Martínez González, Miguel Ángel; Toledo, Estefanía; Ciencias de la Salud; Osasun Zientziak
    Objetivo: Estudiar la correlación de la Telephone Interview for Cognitive Status modificada en español(STICS-m) con el Mini-Mental State Examination (MMSE) y predecir la capacidad de la primera para detectar el desarrollo de demencia. Método: Ciento seis sujetos de un estudio de intervención dietética fueron evaluados personalmente con el MMSE y por teléfono con la STICS-m. La correlación entre ambos se midió con el coeficiente de correlación intraclase (CCI) de consistencia. Además, 932 participantes mayores de 55 años de la cohorte 'Seguimiento Universidad de Navarra' fueron evaluados con la STICS-m. Durante una mediana de seguimiento de 6,5 años, se recogió información sobre el desarrollo de demencia. Mediante regresión logística se estudió la asociación entre la puntuación de la STICS-m o el cambio a 2 años en la puntuación y el riesgo de desarrollar demencia, ajustando por apolipoproteína E, edad y años de educación universitaria. Resultados: El CCI entre el MMSE y la STICS-m fue de 0,31 (intervalo de confianza del 95% [IC95%]:0,13-0,48). La odds ratio (OR) ajustada para el desarrollo de demencia para cada punto adicional en la puntuación basal de la STICS-m fue de 0,85 (IC95%: 0,72-1,02; p = 0,084). Al considerar el cambio en la puntuación a los 2 años como variable independiente, la OR fue de 0,79 (IC95%: 0,67-0,93; p = 0,006).
  • PublicationOpen Access
    Perfil de la demanda urgente e influencia del fútbol televisado en un servicio extrahospitalario en la Zona Básica de Salud de Tafalla, Navarra
    (Ministerio de Sanidad y Consumo, 2003) Pérez Ciordia, Ignacio; Catalán Fabo, Francisca; Zalacain Nicolay, Fernando; Barriendo Antoñanzas, Maite; Solaegui Díaz de Guereñu, Ramón; Guillén Grima, Francisco; Ciencias de la Salud; Osasun Zientziak
    Fundamento: la demanda a los servicios de urgencias, tanto hospitalarios como extrahospitalarios, mantiene un ritmo creciente. El objetivo del presente trabajo es doble: cuantificación y estudio de las características personales de los usuarios demandantes de atención urgente y valorar si el fútbol televisado influye en la utilización del servicio de urgencias. Métodos: Estudio descriptivo longitudinal (9.723 usuarios demandantes) y estudio de casos y controles (1.284 usuarios demandantes) según presencia o no de fútbol televisado mediante modelo de regresión logística. Las asociaciones se han cuantificado mediante la odds ratio (OR). Se excluyen del estudio las consultas telefónicas y las de enfermería. Resultados: El 10,6% de la demanda ha correspondido a consultas en domicilio y se han remitido al hospital el 4,8% del total. El 13,3% de la demanda corresponde a personas desplazadas de otras zonas de salud y son 65 los usuarios hiperfrecuentadores con 8 o más consultas. El mes de agosto (32,3%), el domingo (44,56%) y el grupo horario de 12 a 14 horas (8,38%) son los momento de mayor demanda de atención, siendo las diferencias estadísticamente significativas. El fútbol televisado se asoció a un aumento de la demanda del 19,8% (p<0,001) respecto al periodo control. Conclusiones: Se observa una alta frecuentación a los servicios de urgencia extrahospitalaria, con una importante concentración de la demanda en momentos muy concretos. Es muy importante la atención prestada a personas desplazadas. La retransmisión de fútbol televisado se asocia con una mayor utilización del servicio de urgencias.
  • PublicationOpen Access
    Coverage and development of specialist palliative care services across the World Health Organization European Region (2005-2012): results from a European Association for Palliative Care Task Force survey of 53 countries
    (SAGE, 2016) Centeno, Carlos; Lynch, Thomas; Garralda, Eduardo; Carrasco, José Miguel; Guillén Grima, Francisco; Ciencias de la Salud; Osasun Zientziak
    Background: The evolution of the provision of palliative care specialised services is important for planning and evaluation. Aim: To examine the development between 2005 and 2012 of three specialised palliative care services across the World Health Organization European Region – home care teams, hospital support teams and inpatient palliative care services. Design and setting: Data were extracted and analysed from two editions of the European Association for Palliative Care Atlas of Palliative Care in Europe. Significant development of each type of services was demonstrated by adjusted residual analysis, ratio of services per population and 2012 coverage (relationship between provision of available services and demand services estimated to meet the palliative care needs of a population). For the measurement of palliative care coverage, we used European Association for Palliative Care White Paper recommendations: one home care team per 100,000 inhabitants, one hospital support team per 200,000 inhabitants and one inpatient palliative care service per 200,000 inhabitants. To estimate evolution at the supranational level, mean comparison between years and European sub-regions is presented. Results: Of 53 countries, 46 (87%) provided data. Europe has developed significant home care team, inpatient palliative care service and hospital support team in 2005–2012. The improvement was statistically significant for Western European countries, but not for Central and Eastern countries. Significant development in at least a type of services was in 21 of 46 (46%) countries. The estimations of 2012 coverage for inpatient palliative care service, home care team and hospital support team are 62%, 52% and 31% for Western European and 20%, 14% and 3% for Central and Eastern, respectively. Conclusion: Although there has been a positive development in overall palliative care coverage in Europe between 2005 and 2012, the services available in most countries are still insufficient to meet the palliative care needs of the population.