Ugarte Martínez, María Dolores
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Ugarte Martínez
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María Dolores
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Estadística, Informática y Matemáticas
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InaMat2. Instituto de Investigación en Materiales Avanzados y Matemáticas
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Publication Open Access High-dimensional order-free multivariate spatial disease mapping(Springer, 2023) Vicente Fuenzalida, Gonzalo; Adin Urtasun, Aritz; Goicoa Mangado, Tomás; Ugarte Martínez, María Dolores; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika; Institute for Advanced Materials and Mathematics - INAMAT2; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, PJUPNA2001Despite the amount of research on disease mapping in recent years, the use of multivariate models for areal spatial data remains limited due to difficulties in implementation and computational burden. These problems are exacerbated when the number of areas is very large. In this paper, we introduce an order-free multivariate scalable Bayesian modelling approach to smooth mortality (or incidence) risks of several diseases simultaneously. The proposal partitions the spatial domain into smaller subregions, fits multivariate models in each subdivision and obtains the posterior distribution of the relative risks across the entire spatial domain. The approach also provides posterior correlations among the spatial patterns of the diseases in each partition that are combined through a consensus Monte Carlo algorithm to obtain correlations for the whole study region. We implement the proposal using integrated nested Laplace approximations (INLA) in the R package bigDM and use it to jointly analyse colorectal, lung, and stomach cancer mortality data in Spanish municipalities. The new proposal allows for the analysis of large datasets and yields superior results compared to fitting a single multivariate model. Additionally, it facilitates statistical inference through local homogeneous models, which may be more appropriate than a global homogeneous model when dealing with a large number of areas.Publication Open Access Predicting cancer incidence in regions without population-based cancer registries using mortality(Oxford University Press, 2023) Retegui Goñi, Garazi; Etxeberria Andueza, Jaione; Riebler, Andrea; Ugarte Martínez, María Dolores; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika; Institute for Advanced Materials and Mathematics - INAMAT2; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, PJUPNA2018-11Cancer incidence numbers are routinely recorded by national or regional population-based cancer registries (PBCRs). However, in most southern European countries, the local PBCRs cover only a fraction of the country. Therefore, national cancer incidence can be only obtained through estimation methods. In this paper, we predict incidence rates in areas without cancer registry using multivariate spatial models modelling jointly cancer incidence and mortality. To evaluate the proposal, we use cancer incidence and mortality data from all the German states. We also conduct a simulation study by mimicking the real case of Spain considering different scenarios depending on the similarity of spatial patterns between incidence and mortality, the levels of lethality, and varying the amount of incidence data available. The new proposal provides good interval estimates in regions without PBCRs and reduces the relative error in estimating national incidence compared to one of the most widely used methodologies.Publication Open Access Multivariate Bayesian spatio-temporal P-spline models to analyze crimes against women(Oxford University Press, 2021) Vicente Fuenzalida, Gonzalo; Goicoa Mangado, Tomás; Ugarte Martínez, María Dolores; Estatistika, Informatika eta Matematika; Institute for Advanced Materials and Mathematics - INAMAT2; Estadística, Informática y MatemáticasUnivariate spatio-temporal models for areal count data have received great attention in recent years for estimating risks. However, models for studying multivariate responses are less commonly used mainly due to the computational burden. In this article, multivariate spatio-temporal P-spline models are proposed to study different forms of violence against women. Modeling distinct crimes jointly improves the precision of estimates over univariate models and allows to compute correlations among them. The correlation between the spatial and the temporal patterns may suggest connections among the different crimes that will certainly benefit a thorough comprehension of this problem that affects millions of women around the world. The models are fitted using integrated nested Laplace approximations and are used to analyze four distinct crimes against women at district level in the Indian state of Maharashtra during the period 2001-2013.