Navarro Amezqueta, Ion
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Navarro Amezqueta
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Ion
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Ciencias de la Salud
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Publication Open Access Energy metabolism during repeated sets of leg press exercise leading to failure or not(Public Library of Science, 2012) Gorostiaga Ayestarán, Esteban; Navarro Amezqueta, Ion; Calbet, José A. L.; Hellsten, Ylva; Cusso, Roser; Guerrero, Mario; Granados, Cristina; González Izal, Miriam; Ibáñez Santos, Javier; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun ZientziakThis investigation examined the influence of the number of repetitions per set on power output and muscle metabolism during leg press exercise. Six trained men (age 3466 yr) randomly performed either 5 sets of 10 repetitions (10REP), or 10 sets of 5 repetitions (5REP) of bilateral leg press exercise, with the same initial load and rest intervals between sets. Muscle biopsies (vastus lateralis) were taken before the first set, and after the first and the final sets. Compared with 5REP, 10REP resulted in a markedly greater decrease (P,0.05) of the power output, muscle PCr and ATP content, and markedly higher (P,0.05) levels of muscle lactate and IMP. Significant correlations (P,0.01) were observed between changes in muscle PCr and muscle lactate (R2 = 0.46), between changes in muscle PCr and IMP (R2 = 0.44) as well as between changes in power output and changes in muscle ATP (R2 = 0.59) and lactate (R2 = 0.64) levels. Reducing the number of repetitions per set by 50% causes a lower disruption to the energy balance in the muscle. The correlations suggest that the changes in PCr and muscle lactate mainly occur simultaneously during exercise, whereas IMP only accumulates when PCr levels are low. The decrease in ATP stores may contribute to fatigue.Publication Open Access Changes in muscle and blood metabolites and power output during high-intensity bilateral leg press exercise, with special reference to the effect of leading or not leading to repetition failure(2017) Navarro Amezqueta, Ion; Gorostiaga Ayestarán, Esteban; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun ZientziakThe current PhD dissertation revolves around the influence of the number of repetitions per bout (leading to failure or not) on changes in metabolic and mechanical variables during high-intensity leg press resistance exercise, to attempt to better understand the mechanical and physiological aspects underlying resistance training stimuli that affect adaptations. This doctoral thesis is based on 3 scientific studies that have been published in scientific journals. The first study (Chapter 2) was designed to examine metabolic responses during a single leg press exercise set of 10 repetitions leading to failure (10RM). Study 2 (Chapter 3) was aimed at examining the influence of the number of repetitions per set on changes in muscle metabolites and power output during widely used highintensity intermittent leg press exercise. The last study (Chapter 4) is a descriptive study to investigate the changes in blood metabolites in relation to muscular metabolites and mechanical power output changes.