dc.contributor.author	Retegui Goñi, Garazi
dc.contributor.author	Etxeberria Andueza, Jaione
dc.contributor.author	Ugarte Martínez, María Dolores
dc.contributor.department	Estatistika, Informatika eta Matematika	eu
dc.contributor.department	Institute for Advanced Materials and Mathematics - INAMAT2	en
dc.contributor.department	Estadística, Informática y Matemáticas	es_ES
dc.contributor.funder	Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa	es
dc.date.accessioned	2022-04-07T12:10:22Z
dc.date.available	2022-04-07T12:10:22Z
dc.date.issued	2021
dc.description.abstract	The distribution of lip, oral cavity, and pharynx (LOCP) cancer mortality rates in small domains (defined as the combination of province, age group, and gender) remains unknown in Spain. As many of the LOCP risk factors are preventable, specific prevention programmes could be implemented but this requires a clear specification of the target population. This paper provides an in-depth description of LOCP mortality rates by province, age group and gender, giving a complete overview of the disease. This study also presents a methodological challenge. As the number of LOCP cancer cases in small domains (province, age groups and gender) is scarce, univariate spatial models do not provide reliable results or are even impossible to fit. In view of the close link between LOCP and lung cancer, we consider analyzing them jointly by using shared component models. These models allow information-borrowing among diseases, ultimately providing the analysis of cancer sites with few cases at a very disaggregated level. Results show that males have higher mortality rates than females and these rates increase with age. Regions located in the north of Spain show the highest LOCP cancer mortality rates.	en
dc.description.sponsorship	The work was supported by Project MTM2017-82553-R (AEI, UE), Project PID2020-113125RB-I00/MCIN/ AEI/10.13039/501100011033 and Proyecto Jóvenes Investigadores PJUPNA2018-11.	en
dc.format.extent	10 p.
dc.format.mimetype	application/pdf	en
dc.identifier.doi	10.1038/s41598-021-01765-7
dc.identifier.issn	2045-2322
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/42691
dc.language.iso	eng	en
dc.publisher	Nature Research	en
dc.relation.ispartof	Scientific Reports, 11 (1), 2021
dc.relation.projectID	info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MTM2017-82553-R/ES/	en
dc.relation.projectID	info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-113125RB-I00/ES/	en
dc.relation.publisherversion	https://doi.org/10.1038/s41598-021-01765-7
dc.rights	Creative Commons Attribution 4.0 International	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess	en
dc.rights.accessRights	Acceso abierto / Sarbide irekia	es
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/
dc.subject	Cancer	en
dc.subject	Mortality rates	en
dc.subject	Incidence	en
dc.subject	Predictions	en
dc.subject	Statistics	en
dc.title	Estimating LOCP cancer mortality rates in small domains in Spain using its relationship with lung cancer	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion	en
dc.type.version	Versión publicada / Argitaratu den bertsioa	es
dspace.entity.type	Publication
relation.isAuthorOfPublication	fc50412c-5ed3-4ab9-92bf-ba966d7af279
relation.isAuthorOfPublication	7770971e-9acf-45ee-bb1a-93bf8b5f1c73
relation.isAuthorOfPublication	e87ff19e-9d36-4286-989b-cafd391dff9d
relation.isAuthorOfPublication.latestForDiscovery	7770971e-9acf-45ee-bb1a-93bf8b5f1c73

Publication: Estimating LOCP cancer mortality rates in small domains in Spain using its relationship with lung cancer

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Estimating LOCP cancer mortality rates in small domains in Spain using its relationship with lung cancer