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An antibacterial submicron fiber mat with in situ synthesized silver nanoparticles

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dc.contributor.authorRivero Fuente, Pedro J.
dc.contributor.authorUrrutia Azcona, Aitor
dc.contributor.authorGoicoechea Fernández, Javier
dc.contributor.authorRodríguez, Yoany
dc.contributor.authorCorres Sanz, Jesús María
dc.contributor.authorArregui San Martín, Francisco Javier
dc.contributor.authorMatías Maestro, Ignacio
dc.contributor.departmentIngeniería Eléctrica, Electrónica y de Comunicaciónes_ES
dc.contributor.departmentIngeniaritza Elektrikoa, Elektronikoa eta Telekomunikazio Ingeniaritzaeu
dc.contributor.departmentInstitute of Smart Cities - ISCen
dc.contributor.departmentIngenieríaes_ES
dc.contributor.departmentIngeniaritzaeu
dc.contributor.departmentInstitute for Advanced Materials and Mathematics - INAMAT2en
dc.date.accessioned2024-08-08T08:20:21Z
dc.date.available2024-08-08T08:20:21Z
dc.date.issued2012
dc.date.updated2024-08-08T08:09:47Z
dc.description.abstractThis work presents an alternative approachfor fabricating electrospun submicron highly hydrophilicfiber mats loaded with silver nanoparticles. These fiber matsshow a high efficient antibacterial behavior, very attractivefor applications like wound healing and skin regenerationprocesses. The fabrication method is divided in two steps.First, poly(acrylic acid) (PAA) and b-cyclodextrin (b-CD)submicron fibers were electrospun and further stabilizedusing a thermal treatment, yielding stable hydrogel-likefibers with diameters ranging from 100 nm up to severalmicrons. In the second step, silver ions were loaded into thefibers and then reduced to silver nanoparticles in-situ. Theelectrospinning parameters were adjusted to achieve thedesired properties of the fiber mat (density, size) and after-wards, the characteristics of the silver nanoparticles(amount, size, aggregation) were tuned by controlling thesilver ion loading mechanism. Highly biocide surfaces wereachieved showing more than 99.99% of killing efficiency.The two-step process improves the reproducibility and tun-ability of the fiber mats. To our knowledge, this is the firsttime that stable hydrogel fibers with a highly biocide behav-ior have been fabricated using electrospinning.en
dc.description.sponsorshipSpanish Ministry of Educationand Science, CICYT-FEDER TEC2010-17805, Fuentes DutorFoundation research grant (COIINA).
dc.format.mimetypeapplication/pdf
dc.identifier.citationRivero P.J., Urrutia A., Goicoechea J., Rodriguez Y., Corres J.M., Arregui F.J., Matias I.R. (2012) An antibacterial submicron fiber mat with in situ synthesized silver nanoparticles. Journal of Applied Polymer Science, 126(4), 1228-1235. https://doi.org/10.1002/app.36886.
dc.identifier.doi10.1002/app.36886
dc.identifier.issn0021-8995
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/50634
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofJournal of Applied Polymer Science (2012), vol. 126, núm. 4
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN//TEC2010-17805/ES/en
dc.relation.publisherversionhttps://doi.org/10.1002/app.36886
dc.rights© 2012 Wiley Periodicals, Inc.
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.subjectAntibacterialen
dc.subjectSubmicron fiber maten
dc.subjectSilver nanoparticlesen
dc.titleAn antibacterial submicron fiber mat with in situ synthesized silver nanoparticlesen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePublication
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