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Temporal evolution of brain cancer incidence in the municipalities of Navarre and the Basque Country, Spain

dc.contributor.authorUgarte Martínez, María Dolores
dc.contributor.authorAdin Urtasun, Aritz
dc.contributor.authorGoicoa Mangado, Tomás
dc.contributor.authorCasado, Itziares_ES
dc.contributor.authorArdanaz, Evaes_ES
dc.contributor.authorLarrañaga, Nereaes_ES
dc.contributor.departmentEstatistika eta Ikerketa Operatiboaeu
dc.contributor.departmentInstitute for Advanced Materials and Mathematics - INAMAT2en
dc.contributor.departmentEstadística e Investigación Operativaes_ES
dc.contributor.funderGobierno de Navarra / Nafarroako Gobernua: proyecto 113 Res. 2186/2014es
dc.date.accessioned2016-02-10T11:57:24Z
dc.date.available2016-02-10T11:57:24Z
dc.date.issued2015
dc.description.abstractBackground: Brain cancer incidence rates in Spain are below the European’s average. However, there are two regions in the north of the country, Navarre and the Basque Country, ranked among the European regions with the highest incidence rates for both males and females. Our objective here was two-fold. Firstly, to describe the temporal evolution of the geographical pattern of brain cancer incidence in Navarre and the Basque Country, and secondly, to look for specific high risk areas (municipalities) within these two regions in the study period (1986–2008). Methods: A mixed Poisson model with two levels of spatial effects is used. The model also included two levels of spatial effects (municipalities and local health areas). Model fitting was carried out using penalized quasi-likelihood. High risk regions were detected using upper one-sided confidence intervals. Results: Results revealed a group of high risk areas surrounding Pamplona, the capital city of Navarre, and a few municipalities with significant high risks in the northern part of the region, specifically in the border between Navarre and the Basque Country (Gipuzkoa). The global temporal trend was found to be increasing. Differences were also observed among specific risk evolutions in certain municipalities. Conclusions: Brain cancer incidence in Navarre and the Basque Country (Spain) is still increasing with time. The number of high risk areas within those two regions is also increasing. Our study highlights the need of continuous surveillance of this cancer in the areas of high risk. However, due to the low percentage of cases explained by the known risk factors, primary prevention should be applied as a general recommendation in these populations.en
dc.description.sponsorshipThis research has been supported by the Spanish Ministry of Science and Innovation (project MTM 2011-22664, jointly sponsored with FEDER grants and project MTM2014-51992-R), and by the Health Department of the Navarre Government (project 113, Res.2186/2014).en
dc.format.mimetypeapplication/pdfen
dc.identifier.doi10.1186/s12889-015-2354-5
dc.identifier.issn1471-2458 (Print)
dc.identifier.issn1471-2458 (Electronic)
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/20012
dc.language.isoengen
dc.publisherBioMed Centralen
dc.relation.ispartofBMC Public Health (2015) 15:1018en
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN//MTM2011-22664/ES/en
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO//MTM2014-51992-R/ES/en
dc.relation.publisherversionhttps://dx.doi.org/10.1186/s12889-015-2354-5
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://​creativecommons.​org/​licenses/​by/​4.​0/​), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://​creativecommons.​org/​publicdomain/​zero/​1.​0/​) applies to the data made available in this article, unless otherwise stated.en
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.subjectBrain cancer incidenceen
dc.subjectSmall areasen
dc.subjectSpace-time modelsen
dc.subjectRelative risksen
dc.titleTemporal evolution of brain cancer incidence in the municipalities of Navarre and the Basque Country, Spainen
dc.typeArtículo / Artikuluaes
dc.typeinfo:eu-repo/semantics/articleen
dc.type.versionVersión publicada / Argitaratu den bertsioaes
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dspace.entity.typePublication
relation.isAuthorOfPublicatione87ff19e-9d36-4286-989b-cafd391dff9d
relation.isAuthorOfPublication6f8418c3-eae2-4388-b12a-0690e60d468f
relation.isAuthorOfPublication77ba75f3-a30d-4f01-8cc5-9de6d3a10d8d
relation.isAuthorOfPublication.latestForDiscoverye87ff19e-9d36-4286-989b-cafd391dff9d

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