A lock-in amplifier for magnetic nanoparticle detection using GMI sensors

dc.contributor.authorAlgueta-Miguel, Jose M.
dc.contributor.authorBeato López, Juan Jesús
dc.contributor.authorLópez Martín, Antonio
dc.contributor.authorGómez Polo, Cristina
dc.contributor.departmentCienciases_ES
dc.contributor.departmentZientziakeu
dc.contributor.departmentIngeniería Eléctrica, Electrónica y de Comunicaciónes_ES
dc.contributor.departmentIngeniaritza Elektrikoa, Elektronikoa eta Telekomunikazio Ingeniaritzaeu
dc.contributor.departmentInstitute for Advanced Materials and Mathematics - INAMAT2en
dc.contributor.departmentInstitute of Smart Cities - ISCen
dc.date.accessioned2024-12-02T10:03:43Z
dc.date.available2024-12-02T10:03:43Z
dc.date.issued2024-09-30
dc.date.updated2024-12-02T09:55:09Z
dc.description.abstractA digital lock-in amplifier (LIA) for contactless magnetic nanoparticle (MNP) detection using giant magnetoimpedance (GMI) sensors is presented. The proposed approach is based on the simultaneous detection of the second harmonic amplitude and phase. A Xilinx Artix-7 field-programmable gate array (FPGA) has been employed for efficiently implementing the phase-sensitive detection (PSD) and the subsequent digital processing. The analog GMI sensor interface has been designed for minimizing the dependence of the excitation current on the GMI sensor impedance, also enhancing the rejection of the parasitic second-order distortion produced by the setup. A subsampling process of the analog outputs has been applied, both increasing the effective resolution of the analog-to-digital converter (ADC) and facilitating signal recovery. The proposed system improves the MNP detection capability reported in previous works using the second harmonic amplitude. Moreover, a characterization of the phase response, which had not been previously studied in the literature, is also provided.en
dc.description.sponsorshipThis work was supported by MCIN/AEI/10.13039/501100011033/FEDER, UE, under Grant PID2022-138510OB-C21.
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAlgueta-Miguel, J. M., Beato-López, J. J., López-Martín, A. J., Gómez-Polo, C. (2024). A lock-in amplifier for magnetic nanoparticle detection using GMI sensors. IEEE Transactions on Instrumentation and Measurement, 73, 1-9. https://doi.org/10.1109/TIM.2024.3470988.
dc.identifier.doi10.1109/TIM.2024.3470988
dc.identifier.issn0018-9456
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/52627
dc.language.isoeng
dc.publisherIEEE
dc.relation.ispartofIEEE Transactions on Instrumentation and Measurement (2024), vol. 73, 2006809
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-138510OB-C21/ES/
dc.relation.publisherversionhttps://doi.org/10.1109/TIM.2024.3470988
dc.rights© 2024 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other work.
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.subjectLock-in amplifieren
dc.subjectGMI sensorsen
dc.subjectMagnetic nanoparticlesen
dc.subjectSecond-harmonic detectionen
dc.subjectFPGAen
dc.titleA lock-in amplifier for magnetic nanoparticle detection using GMI sensorsen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoveryd92eec50-9862-440c-9f46-3ad22e06ba95

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