Amyloid structures as biofilm matrix scaffolds

Taglialegna, Agustina; Lasa Uzcudun, Íñigo; Valle Turrillas, Jaione

Publication:
Amyloid structures as biofilm matrix scaffolds

dc.contributor.author	Taglialegna, Agustina
dc.contributor.author	Lasa Uzcudun, Íñigo
dc.contributor.author	Valle Turrillas, Jaione
dc.contributor.department	IdAB. Instituto de Agrobiotecnología / Agrobioteknologiako Institutua	es_ES
dc.date.accessioned	2016-11-04T16:15:02Z
dc.date.available	2017-04-01T23:00:16Z
dc.date.issued	2016
dc.description.abstract	Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward the recognition of amyloid fibers as common building block structures that confer stability to the exopolysaccharide matrix. Here we describe the functional amyloid systems related to biofilm matrix formation in both Gram-negative and Gram-positive bacteria and recent knowledge regarding the interaction of amyloids with other biofilm matrix components such as extracellular DNA (eDNA) and the host immune system. In addition, we summarize the efforts to identify compounds that target amyloid fibers for therapeutic purposes and recent developments that take advantage of the amyloid structure to engineer amyloid fibers of bacterial biofilm matrices for biotechnological applications.	en
dc.description.sponsorship	This work, including the efforts of Jaione Valle, was funded by Ministerio de Economía y Competitividad (MINECO) (AGL2011-23954). This work, including the efforts of Íñigo Lasa, was funded by Ministerio de Economía y Competitividad (MINECO) (BIO2011-30503-C02-02 and BIO2014-53530-R).	en
dc.embargo.lift	2017-04-01
dc.embargo.terms	2017-04-01
dc.format.mimetype	application/pdf	en
dc.identifier.doi	10.1128/JB.00122-16
dc.identifier.issn	0021-9193 (Print)
dc.identifier.issn	1098-5530 (Electronic)
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/22614
dc.language.iso	eng	en
dc.publisher	American Society for Microbiology	en
dc.relation.ispartof	Journal of Bacteriology, October 2016, vol. 198, no. 19, 2579-2588	en
dc.relation.projectID	info:eu-repo/grantAgreement/ES/6PN/AGL2011-23954	en
dc.relation.projectID	info:eu-repo/grantAgreement/MICINN//BIO2011-30503-C02-02/ES/	en
dc.relation.projectID	info:eu-repo/grantAgreement/MINECO//BIO2014-53530-R/ES/	en
dc.relation.publisherversion	https://dx.doi.org/10.1128/JB.00122-16
dc.rights	© 2016, American Society for Microbiology. All Rights Reserved.	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.subject	Amyloid fibers	en
dc.subject	Bacterial biofilm matrices	en
dc.subject	Gram-negative bacteria	en
dc.subject	Gram-positive bacteria	en
dc.title	Amyloid structures as biofilm matrix scaffolds	en
dc.type	info:eu-repo/semantics/article
dc.type.version	Versión aceptada / Onetsi den bertsioa	es
dc.type.version	info:eu-repo/semantics/acceptedVersion	en
dspace.entity.type	Publication
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