Reply to Thinnes: to include plasmalemmal VDAC/porin pays

Date

2012-02-06

Authors

Ujwal, Rachna
Hillerdal, Carl-Olof
Kullman, Lisen
Rostovtseva, Tatiana K.
Abramson, Jeff

Director

Publisher

American Society for Biochemistry and Molecular Biology
Acceso abierto / Sarbide irekia
Otros / Bestelakoak
Versión publicada / Argitaratu den bertsioa

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No disponible en Scopus

Abstract

Our study was focused entirely on the properties of VDAC from the mitochondrial outer membrane; therefore, discussion of possible VDAC N-terminal exposure on the plasma membrane surface is totally irrelevant to this work. Our experiments did not aim to test the position of the VDAC1Nterminus in the channel¿s closed conformation. We cannot rule out the possibility that, when closed, the first amino acids of the VDAC N terminus could be exposed at the channel entrance, but these speculations are beyond our present study.

Description

Keywords

Voltage-dependent anion channel (VDAC), Mitochondrial outer membrane

Department

Ciencias de la Salud / Osasun Zientziak

Faculty/School

Degree

Doctorate program

item.page.cita

Teijido, O., Ujwal, R., Hillerdal, C. O., Kullman, L., Rostovtseva, T. K., Abramson, J. (2012). Reply to Thinnes: to include plasmalemmal VDAC/porin pays. Journal of the Biological Chemistry, 287(15), 12156-12156. https://doi.org/10.1074/jbc.N111.314229.

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Creative Commons Attribution 4.0 International

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