• ADAM12 is a potential therapeutic target regulated by hypomethylation in triple-negative breast cancer 

      Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Ruiz de Azúa, Yerani (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and currently lacks any effective targeted therapy. Since epigenetic alterations are a common event in TNBC, DNA methylation profiling can ...
    • CDH22 hypermethylation is an independent prognostic biomarker in breast cancer 

      Martín Sánchez, Esperanza; Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero Setas, David (BioMed Central, 2017)   Artículo / Artikulua  OpenAccess
      Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ...
    • CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer 

      Martín Sánchez, Esperanza; Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Blanco Luquin, Idoia; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Pérez Janices, Noemi; Escors Murugarren, David; Megías, Diego (Impact Journals, 2017)   Artículo / Artikulua  OpenAccess
      The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation ...
    • Clinical, histopathologic and genetic features of rhabdoid meningiomas 

      Garrido Ruiz, Patricia Alejandra; González-Tablas, María; Pasco Peña, Alejandro; Zelaya Huerta, María Victoria Upna Orcid; Ortiz, Javier; Otero, Álvaro; Corchete, Luis Antonio; Ludeña, María Dolores; Caballero Martínez, María Cristina; Córdoba Iturriagagoitia, Alicia; Fernández, Inmaculada Catalina; González-Carreró Fojón, Joaquín; Hernández Laín, Aurelio; Orfao, Alberto; Tabernero, María Dolores (MDPI, 2023)   Artículo / Artikulua  OpenAccess
      Rhabdoid meningiomas (RM) shows heterogeneous histological findings, and a wide variety of chromosomal copy number alterations (CNA) are associated with an unpredictable course of the disease. In this study, we analyzed a ...
    • A DNA methylation-based gene signature can predict triple-negative breast cancer diagnosis 

      Mendaza Lainez, Saioa Upna; Guerrero Setas, David; Monreal Santesteban, Iñaki; Ulazia Garmendia, Ane; Córdoba Iturriagagoitia, Alicia; Cruz, Susana de la; Martín Sánchez, Esperanza (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Triple-negative breast cancer (TNBC) is the most aggressive breast cancer (BC) subtype and lacks targeted treatment. It is diagnosed by the absence of immunohistochemical expression of several biomarkers, but this method ...
    • Dual staining for p 167Ki67 is a more specific test than cytology for triage of HPV-positive women 

      Areán Cuns, Carolina; Mercado Gutiérrez, María R.; Paniello Alastruey, Irene Upna Orcid; Mallor Giménez, Fermín Upna Orcid; Córdoba Iturriagagoitia, Alicia; Lozano Escario, María; Santamaria Martínez, Mercedes (Springer, 2018)   Artículo / Artikulua
    • Subtipos moleculares del cáncer de mama: implicaciones pronósticas y características clínicas e inmunohistoquímicas 

      Arrechea Irigoyen, María Asunción; Vicente García, Francisco; Córdoba Iturriagagoitia, Alicia; Ibáñez Beroiz, B. Upna Orcid; Santamaría Martínez, M.; Guillén Grima, Francisco Upna Orcid (Gobierno de Navarra, 2011)   Artículo / Artikulua  OpenAccess
      Fundamento. Los carcinomas de mama representan un grupo heterogéneo de tumores, tanto en su comportamiento clínico como pronóstico. El objetivo del presente trabajo es clasificar los carcinomas de mama en subtipos ...
    • ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer 

      Fernández de los Reyes, Irene; Gómez Dorronsoro, María Luisa; Monreal Santesteban, Iñaki; Fernández-Fernández, Agustín; Fraga, Mario; Azcue Sanromán, Pablo; Alonso, Laura; Fernández-Marlasca, Beatriz; Suárez Alecha, Javier; Córdoba Iturriagagoitia, Alicia; Guerrero Setas, David (BMC, 2023)   Artículo / Artikulua  OpenAccess
      Background: Colon cancer (CC) is a heterogeneous disease that is categorized into four Consensus Molecular Subtypes (CMS) according to gene expression. Patients with loco-regional CC (stages II/III) lack prognostic factors, ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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