Listar Artículos de revista DCS - OZS Aldizkari artikuluak por tema "DNA methylation"
Mostrando ítems 1-11 de 11
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ADAM12 is a potential therapeutic target regulated by hypomethylation in triple-negative breast cancer
Mendaza Lainez, Saioa
; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Ruiz de Azúa, Yerani (MDPI, 2020)
Artículo / Artikulua 
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and currently lacks any effective targeted therapy. Since epigenetic alterations are a common event in TNBC, DNA methylation profiling can ... -
CDH22 hypermethylation is an independent prognostic biomarker in breast cancer
Martín Sánchez, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero Setas, David (BioMed Central, 2017)
Artículo / Artikulua
Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ... -
CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer
Martín Sánchez, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Blanco Luquin, Idoia; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Pérez Janices, Noemi; Escors Murugarren, David; Megías, Diego (Impact Journals, 2017)
Artículo / Artikulua
The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation ... -
Deciphering CHFR role in pancreatic ductal adenocarcinoma
González Borja, Iranzu; Alors-Pérez, Emilia; Amat Villegas, Irene; Alonso, Laura; Viyuela-García, Cristina; Goñi Irigoyen, Saioa 
; Reyes, José C.; Ceballos-Chávez, María; Hernández García, Irene; Sánchez-Frías, Marina E.; Santamaría, Enrique; Razquin, Socorro; Arjona Sánchez, Álvaro; Arrazubi, Virginia; Pérez Sanz, Jairo; Vera García, Ruth; Fernández Irigoyen, Joaquín ; Castaño, Justo P.; Viúdez, Antonio (Frontiers Media, 2021)
Artículo / Artikulua
Checkpoint with forkhead-associated and ring finger domains (CHFR) has been proposed as a predictive and prognosis biomarker for different tumor types, but its role in pancreatic ductal adenocarcinoma (PDAC) remains unknown. ... -
A DNA methylation-based gene signature can predict triple-negative breast cancer diagnosis
Mendaza Lainez, Saioa; Guerrero Setas, David; Monreal Santesteban, Iñaki; Ulazia Garmendia, Ane; Córdoba Iturriagagoitia, Alicia; Cruz, Susana de la; Martín Sánchez, Esperanza (MDPI, 2021)
Artículo / Artikulua
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer (BC) subtype and lacks targeted treatment. It is diagnosed by the absence of immunohistochemical expression of several biomarkers, but this method ... -
Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients
Kular, Lara; Klose, Dennis; Urdánoz Casado, Amaya ; Ewing, Ewoud; Planell, Nuria; Gómez-Cabrero, David; Needhamsen, Maria; Jagodic, Maja (Frontiers Media, 2022)
Artículo / Artikulua
Background: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS) characterized by irreversible disability at later progressive stages. A growing body of ... -
Epigenetic regulation of microRNAs in cancer: shortening the distance from bench to bedside
Pajares Villandiego, María Josefa ; Alemany Cosme, Ester; Goñi Irigoyen, Saioa ; Bandrés Elizalde, Eva ; Palanca Ballester, Cora; Sandoval, Juan (MDPI, 2021)
Artículo / Artikulua
Cancer is a complex disease involving alterations of multiple processes, with both genetic and epigenetic features contributing as core factors to the disease. In recent years, it has become evident that non-coding RNAs ... -
Methods for analysis of specific DNA methylation status
Pajares Villandiego, María Josefa ; Palanca Ballester, Cora; Urtasun Alonso, Raquel ; Alemany Cosme, Ester; Lahoz, Agustín; Sandoval, Juan (Elevier, 2021)
Artículo / Artikulua
Methylation of CpG dinucleotides plays a crucial role in the regulation of gene expression and therefore in the development of different pathologies. Aberrant methylation has been associated to the majority of the diseases, ... -
NXN gene epigenetic changes in an adult neurogenesis model of Alzheimer's disease
Blanco Luquin, Idoia; Acha Santamaría, Blanca ; Urdánoz Casado, Amaya ; Gómez Orte, Eva; Roldán, Miren; Pérez Rodríguez, Diego R.; Cabello, Juan; Mendióroz Iriarte, Maite (MDPI, 2022)
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In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis in vitro model to recapitulate DNA methylation marks in the ... -
Telomere length correlates with subtelomeric DNA methylation in long-term mindfulness practitioners
Mendióroz Iriarte, Maite; Puebla Guedea, Marta; Montero Marín, Jesús; Urdánoz Casado, Amaya ; Labarga, Alberto (Nature Research, 2020)
Artículo / Artikulua
Mindfulness and meditation techniques have proven successful for the reduction of stress and improvement in general health. In addition, meditation is linked to longevity and longer telomere length, a proposed biomarker ... -
ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer
(BMC, 2023) Artículo / Artikulua
Background: Colon cancer (CC) is a heterogeneous disease that is categorized into four Consensus Molecular Subtypes (CMS) according to gene expression. Patients with loco-regional CC (stages II/III) lack prognostic factors, ...
