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TNF-α-secreting tumor-infiltrated monocytes play a pivotal role during anti-PD-L1 immunotherapy
(Frontiers Media, 2022)
Artículo / Artikulua,
Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1+ NSCLC patients are refractory to anti-PD-L1 therapy. ...
Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: identification of a Se-indomethacin analog as a potential therapeutic for breast cancer
(Elsevier, 2022)
Artículo / Artikulua,
A total of twenty-five novel carboxylic acid, methylester, methylamide or cyano nonsteroidal anti-inflammatory drug (NSAID) derivatives incorporating Se in the chemical form of selenoester were reported. Twenty Se-NSAID ...
Inhibiting the two‑component system GraXRS with verteporfin to combat Staphylococcus aureus infections
(Nature Research, 2020)
Artículo / Artikulua,
Infections caused by Staphylococcus aureus pose a serious and sometimes fatal health issue. With the
aim of exploring a novel therapeutic approach, we chose GraXRS, a Two-Component System (TCS)
that determines bacterial ...
Association between parental attitudes towards their offspring’s diet and children’s actual dietary habits: the SENDO project
(Arán Ediciones, 2021)
info:eu-repo/semantics/article,
Introducción: la etapa preescolar es un período crítico para enseñar y modelar hábitos saludables que influyan positivamente en la salud y el bienestar de los niños a lo largo de su vida. Objetivos: evaluar la influencia ...
Relevance of sex, age and gait kinematics when predicting fall-risk and mortality in older adults
(Elsevier, 2020)
info:eu-repo/semantics/article,
Approximately one-third of elderly people fall each year with severe consequences, including death. The aim of this study was to identify the most relevant features to be considered to maximize the accuracy of a logistic ...
Papel de la nutrición en la recuperación del jugador de baloncesto
(Arán Ediciones, 2020)
info:eu-repo/semantics/article,
Son escasos los trabajos que ofrecen una solución práctica a los requerimientos nutricionales del baloncesto actual. Este trabajo ofrece una propuesta teórico-práctica, basada en una revisión de la literatura de los últimos ...
La ciencia determinará el origen de Colón
(Sociedad Cultural Peña Pregón, 2020)
info:eu-repo/semantics/article,
Todavía permanece oculto el origen de Don Cristóbal Colón, descubridor de las Indias Occidentales. El enigma no fue casual, sino querido por él y por los poderes políticos de la época. Entre las tesis más fiables, que el ...
Horizonte 2025 para la atención a la cronicidad
(Gobierno de Navarra. Departamento de Salud, 2020)
info:eu-repo/semantics/article,
Reflexiones en torno al futuro de la atención a los pacientes con enfermedades crónicas. Las autoras apuestan por una estrategia integral e integradora, multidisciplinar, coordinada entre niveles asistenciales, intersectorial, ...
Deciphering the constrained total energy expenditure model in humans by associating accelerometer-measured physical activity from wrist and hip
(Nature Research, 2021)
Artículo / Artikulua,
The constrained total energy expenditure (TEE) model posits that progressive increases in physical activity (PA) lead to increases in TEE; but after certain PA threshold, TEE plateaus. Then, a compensatory reduction in the ...
Handgrip strength as a moderator of the influence of age on olfactory impairment in US adult population ≥ 40 years of age
(Nature Research, 2021)
Artículo / Artikulua,
The aim of this study was to determine whether handgrip strength attenuates the negative relationship between age and olfactory function in a representative US population sample 40 years old and over. A cross-sectional ...