Listar Colecciones de Investigación y Producción Científica - Ikerketa eta ekoizpen zientifikoko Bildumak por autor "Roldán, Miren"
Mostrando ítems 1-6 de 6
-
Association of blood-based DNA methylation markers with late-onset alzheimer disease: a potential diagnostic approach
Acha Santamaría, Blanca
; Corroza, Jon; Sánchez Ruiz de Gordoa, Javier ; Cabello, Carolina; Robles Solano, Maitane; Méndez López, Iván ; Macías, Mónica; Zueco, Sara; Roldán, Miren; Urdánoz Casado, Amaya ; Jericó Pascual, Ivonne; Erro Aguirre, María Elena; Alcolea, Daniel; Lleo, Alberto; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (Lippincott Williams & WilkinsAmerican Academy of Neurology, 2023)
Artículo / Artikulua 
Background and Objectives: There is an urgent need to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent advances in blood-based measurements of phosphorylated tau (pTau) species are promising ... -
Gender-dependent deregulation of linear and circular RNA variants of homer1 in the entorhinal cortex of Alzheimer’s disease
Urdánoz Casado, Amaya ; Sánchez Ruiz de Gordoa, Javier ; Robles Solano, Maitane; Acha Santamaría, Blanca ; Roldán, Miren; Zelaya Huerta, María Victoria ; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2021)
Artículo / Artikulua
The HOMER1 gene is involved in synaptic plasticity, learning and memory. Recent studies show that circular RNA derived from HOMER1 (circHOMER1) expression is altered in some Alzheimer’s disease (AD) brain regions. In ... -
Is the phenotype designation by PSP-MDS criteria stable throughout the disease course and consistent with tau distribution?
Sánchez Ruiz de Gordoa, Javier ; Zelaya Huerta, María Victoria ; Tellechea-Aramburo, Paula; Acha Santamaría, Blanca ; Roldán, Miren; López Molina, Carlos ; Coca, Valle; Galbete Jiménez, Arkaitz ; Mendióroz Iriarte, Maite; Erro Aguirre, María Elena (Frontiers Media, 2022)
Artículo / Artikulua
Introduction: the MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do not discriminate the phenotype diversity. Our purpose was to search for anatomopathological differences among PSP phenotypes ... -
Liquid biopsy in alzheimer's disease patients reveals epigenetic changes in the PRLHR gene
Macías, Mónica; Acha Santamaría, Blanca ; Corroza, Jon; Urdánoz Casado, Amaya ; Roldán, Miren; Robles, Maitane; Sánchez Ruiz de Gordoa, Javier ; Erro Aguirre, María Elena; Jericó Pascual, Ivonne; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2023)
Artículo / Artikulua
In recent years, new DNA methylation variants have been reported in genes biologically relevant to Alzheimer’s disease (AD) in human brain tissue. However, this AD-specific epigenetic information remains brain-locked and ... -
NXN gene epigenetic changes in an adult neurogenesis model of Alzheimer's disease
Blanco Luquin, Idoia; Acha Santamaría, Blanca ; Urdánoz Casado, Amaya ; Gómez Orte, Eva; Roldán, Miren; Pérez Rodríguez, Diego R.; Cabello, Juan; Mendióroz Iriarte, Maite (MDPI, 2022)
Artículo / Artikulua
In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis in vitro model to recapitulate DNA methylation marks in the ... -
Profile of TREM2-derived circRNA and mRNA variants in the entorhinal cortex of Alzheimer's disease patients
Urdánoz Casado, Amaya; Sánchez Ruiz de Gordoa, Javier; Robles, Maitane; Roldán, Miren; Zelaya Huerta, María Victoria ; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2022)
Artículo / Artikulua
Genetic variants in TREM2, a microglia-related gene, are well-known risk factors for Alzheimer’s disease (AD). Here, we report that TREM2 originates from circular RNAs (circRNAs), a novel class of non-coding RNAs ...
