Adherence to the Mediterranean diet reduces mortality in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain)
Fecha
2011Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión publicada / Argitaratu den bertsioa
Impacto
|
10.1017/s0007114511002078
Resumen
Epidemiological studies show that adherence to a Mediterranean diet (MD) increases longevity; however, few studies are restricted to
Mediterranean populations or explore the effect of a MD pattern that directly incorporates olive oil. Therefore the relationship between
adherence to the MD and mortality was studied within the the Spanish cohort of the European Prospective Investigation into Cancer ...
[++]
Epidemiological studies show that adherence to a Mediterranean diet (MD) increases longevity; however, few studies are restricted to
Mediterranean populations or explore the effect of a MD pattern that directly incorporates olive oil. Therefore the relationship between
adherence to the MD and mortality was studied within the the Spanish cohort of the European Prospective Investigation into Cancer
and Nutrition (EPIC-Spain). The EPIC-Spain analysis included 40 622 participants (37·7% males) aged 29–69 years who were recruited
from five Spanish regions in 1992–1996. During a mean follow-up of 13·4 years, 1855 deaths were documented: 913 from cancer, 399
from CVD, 425 from other causes and 118 from unknown causes of death. Risk of all-cause and cause-specific mortality was assessed
according to the level of adherence to a relative MD (rMED) score, measured using an 18-unit scale incorporating nine selected dietary
components. A high compared with a low rMED score was associated with a significant reduction in mortality from all causes (hazard
ratio (HR) 0·79; 95% CI 0·69, 0·91), from CVD (HR 0·66; 95% CI 0·49, 0·89), but not from overall cancer (HR 0·92; 95% CI 0·75, 1·12).
A 2-unit increase in rMED score was associated with a 6% (P,0·001) decreased risk of all-cause mortality. A high olive oil intake and
moderate alcohol consumption contributed most to this association. In this Spanish cohort, following an olive oil-rich MD was related
to a significant reduction in all-cause mortality, and reduced the risk of mortality from CVD. These results support the important role
that the MD pattern has on reducing mortality in Mediterranean countries. [--]
Materias
Mediterranean diet,
Mortality,
EPIC-Spain,
Cohort studies
Editor
Cambridge University Press
Publicado en
British Journal of Nutrition, (2011), 106, 1581–1591
Departamento
Universidad Pública de Navarra. Departamento de Estadística e Investigación Operativa /
Nafarroako Unibertsitate Publikoa. Estatistika eta Ikerketa Operatiboa Saila
Versión del editor
Entidades Financiadoras
The present study was supported by the European Commission
(DG-SANCO), the International Agency for Research on
Cancer (IARC), the Health Research Funds (FIS) of the Spanish
Ministry of Health (grant no. Exp P10710130) from the Instituto
de Salud Carlos III; the Spanish Regional Governments
of Andalucía, Asturias, Basque Country, Murcia (no. 6236)
and Navarra and the Catalan Institute of Oncology, and Red
Temática de Investigación Cooperativa en Cáncer (RTICC)
(grant no. C03/10, R06/0020).
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