Listar por tema "Staphylococcus aureus"
Mostrando ítems 41-51 de 51
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Role of biofilm-associated protein bap in the pathogenesis of bovine Staphylococcus aureus
Staphylococcus aureus is a common cause of intramammary infections, which frequently become chronic, associated with the ability of the bacteria to produce biofilm. Here, we report a relationship between the ability to ... -
Role of sodium salicylate in Staphylococcus aureus quorum sensing, virulence, biofilm formation and antimicrobial susceptibility
The widespread threat of antibiotic resistance requires new treatment options. Disrupting bacterial communication, quorum sensing (QS), has the potential to reduce pathogenesis by decreasing bacterial virulence. The aim ... -
SarA positively controls Bap-dependent biofilm formation in Staphylococcus aureus
The biofilm-associated protein Bap is a staphylococcal surface protein involved in biofilm formation. We investigated the influence of the global regulatory locus sarA on bap expression and Bap-dependent biofilm formation ... -
Sensory deprivation in Staphylococcus aureus
Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ... -
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ... -
Staphylococcus aureus develops an alternative, ica-independent biofilm in the absence of the arlRS two-component system
The biofilm formation capacity of Staphylococcus aureus clinical isolates is considered an important virulence factor for the establishment of chronic infections. Environmental conditions affect the biofilm formation capacity ... -
Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins
Staphylococcus aureus pathogenicity islands (SaPIs) have an intimate relationship with temperate staphylococcal phages. During phage growth, SaPIs are induced to replicate and are efficiently encapsidated into special small ... -
Staphylococcus aureus susceptibility to complestatin and corbomycin depends on the VraSR two-component system
The overuse of antibiotics in humans and livestock has driven the emergence and spread of antimicrobial resistance and has therefore prompted research on the discovery of novel antibiotics. Complestatin (Cm) and corbomycin ... -
Study of the molecular mechanisms underlying Bap-mediated cell-cell interactions in Staphylococcus aureus
La mayoría de los microorganismos son capaces de vivir en comunidades sésiles, siendo esta forma de crecimiento bastante más frecuente que la forma de vida planctónica. En estas comunidades microbianas, conocidas como ... -
A systematic evaluation of the two-component systems network reveals that ArlRS is a key regulator of catheter colonization by Staphylococcus aureus
Two-component systems (TCS) are modular signal transduction pathways that allow cells to adapt to prevailing environmental conditions by modifying cellular physiology. Staphylococcus aureus has 16 TCSs to adapt to the ... -
Systematic reconstruction of the complete two-component sensorial network in staphylococcus aureus
In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different ...