Listar Dpto. Ciencias de la Salud - Osasun Zientziak Saila por título
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Obesidad en la era del sedentarismo. Programa de intervención con ejercicio
Se expone un estudio piloto realizado con el objetivo de evaluar el efecto de un programa de ejercicio físico en adultos con sobrepeso/obesidad antes de su implantación en la comunidad. -
Obesity-and lipid-related parameters in the identification of older adults with a high risk of prediabetes according to the American diabetes association: an analysis of the 2015 health, well-being, and aging study
This study evaluated the predictive ability of 11 obesity-and lipid-related parameters, including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WtHR), body roundness index (BRI), 'A' body-shape ... -
Objetivos de presión arterial para la hipertensión en pacientes con enfermedad renal crónica
(2022) Tesis doctoral / Doktoretza tesiaThe objective of this doctoral thesis is to determine whether intensive blood pressure targets are associated with a reduction in mortality and morbidity as compared with standard blood pressure targets in the treatment ... -
Objetivos de tensión arterial en el tratamiento de pacientes con hipertensión y enfermedad cardiovascular
Antecedentes: La hipertensión es una importante causa prevenible de morbilidad y mortalidad prematura. Los pacientes con enfermedad cardiovascular establecida se hallan en un especial alto riesgo, de modo que algunas ... -
Olas de esperanza familiar: narrativas de las familias en el contexto de la enfermedad crónica pediátrica
(Universidad de São Paulo, Escuela de Enfermería de Ribeirão PretoCentro Colaborador de la OPS/OMS para el Desarrollo de la Investigación en Enfermería, 2021) Artículo / ArtikuluaObjetivo: analizar las narrativas sobre la experiencia de esperanza de las familias en el contexto de la enfermedad crónica pediátrica. Método: investigación narrativa que utilizó la Enfermería de Sistemas Familiares como ... -
Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies
Background: Previous studies have shown that functional systemic immunity is required for the efficacy of PD-1/PD-L1 blockade immunotherapies in cancer. Hence, systemic reprogramming of immunosuppressive dysfunctional ... -
Olfaction and neurodegeneration: olfactory proteotyping across proteinopathies
La disfunción olfatoria es un síntoma temprano y común en diversas enfermedades neurodegenerativas (ENs). Según el grado de disfunción olfatoria que presentan, existen ENs con disfunción olfatoria pronunciada, como la ... -
Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression
Olfactory dysfunction is among the earliest features of Alzheimer’s disease (AD). Although neuropathological abnormalities have been detected in the olfactory bulb (OB), little is known about its dynamic biology. Here, OB- ... -
Olfactory bulb proteomics reveals widespread proteostatic disturbances in mixed dementia and guides for potential serum biomarkers to discriminate alzheimer disease and mixed dementia phenotypes
The most common form of mixed dementia (MixD) is constituted by abnormal protein deposits associated with Alzheimer's disease (AD) that coexist with vascular disease. Although olfactory dysfunction is considered a clinical ... -
Omics approaches in pancreatic adenocarcinoma
Pancreatic ductal adenocarcinoma, which represents 80% of pancreatic cancers, is mainly diagnosed when treatment with curative intent is not possible. Consequently, the overall five-year survival rate is extremely dismal—around ... -
Oncolytic adenovirus Delta-24-RGD induces a widespread glioma proteotype remodeling during autophagy
Adenovirus Delta-24-RGD has shown a remarkable efficacy in a phase I clinical trial for glioblastoma. Delta-24-RGD induces autophagy in glioma cells, however, the molecular derangements associated with Delta-24-RGD infection ... -
Operones no-contiguos: una nueva estrategia para coordinar la expresión de genes en bacterias
En esta tesis demostramos la existencia de un nivel superior de organización en la estructura del operón que denominamos operón no-contiguo y que consiste en un operón que contiene un gen o genes que se transcriben en la ... -
Opposite cannabis-cognition associations in psychotic patients depending on family history
The objective of this study is to investigate cognitive performance in a first-episode psychosis sample, when stratifying the interaction by cannabis use and familial or non-familial psychosis. Hierarchical-regression ... -
Optimal reactive strength index: is it an accurate variable to optimize plyometric training effects on measures of physical fitness in young soccer players?
This study aimed to compare the effects of drop-jump training using a fixed drop-box height (i.e., 30-cm [FIXED]) vs. an optimal (OPT) drop-box height (i.e., 10-cm to 40-cm: generating an OPT reactive strength index [RSI]) ... -
The order effect of combined endurance and strength loadings on force and hormone responses: effects of prolonged training
Purpose To examine acute responses and recovery of force and serum hormones to combined endurance and strength loadings utilizing different orders of exercises before and after training. Methods Physically active men were ... -
Organoseleno cytostatic derivatives: autophagic cell death with AMPK and JNK activation
Selenocyanates and diselenides are potential antitumor agents. Here we report two series of selenium derivatives related to selenocyanates and diselenides containing carboxylic, amide and imide moieties. These compounds ... -
Origen de los programas de cribado neonatal y sus inicios en España
Los primeros programas de cribado neonatal de errores congénitos del metabolismo y otras enfermedades endocrinas comenzaron a finales de los años cincuenta y, una década más tarde, se introdujeron en España. Desde ... -
Overall proportion of orthorexia nervosa symptoms: a systematic review and meta-analysis including 30 476 individuals from 18 countries
Background. To date, no previous meta-analysis has determined the overall proportion of orthorexia nervosa symptoms on a global scale. The aim of the present study was 2-fold: first, to establish the overall proportion ... -
El ozono no consigue la desinfección de los vehículos de emergencias de virus similares al SARS-CoV-2
Ante la pandemia generada por el coronavirus SARS-CoV-2, la desinfección de los vehículos de emergencias supone una cuestión crucial. No en vano, son medio de transporte de pacientes contagiados y podrían ser vector de ... -
Papel de la galectina-3 en la degeneración valvular en pacientes con estenosis aórtica severa
Objetivo: La estenosis aórtica degenerativa (EA) es una enfermedad inflamatoria crónica. La calcificación juega un papel importante en la progresión de la enfermedad. La Galectina-3 (Gal-3) es una molécula proinflamatoria ...