Listar Dpto. Ciencias de la Salud - Osasun Zientziak Saila por autor "Parini, Paolo"

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Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

Liang, Ning; Damdimopoulos, Anastasius; Goñi Irigoyen, Saioa ; Huang, Zhiqiang; Vedin, Lise-Lotte; Jakobsson, Tomas; Giudici, Marco; Ahmed, Osman; Pedrelli, Matteo; Barilla, Serena; Alzaid, Fawaz; Mendoza, Arturo; Schröder, Tarja; Kuiper, Raoul; Parini, Paolo; Hollenberg, Anthony; Lefebvre, Philippe; Francque, Sven; Van Gaal, Luc; Staels, Bart; Venteclef, Nicolas; Treuter, Eckardt; Fan, Rongrong (Nature Research, 2019) Artículo / Artikulua

Obesity triggers the development of non-alcoholic fatty liver disease (NAFLD), which involves alterations of regulatory transcription networks and epigenomes in hepatocytes. Here we demonstrate that G protein pathway ...