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Normative reference values for the 20 m shuttle-run test in a population-based sample of school-aged youth in Bogota, Colombia: the FUPRECOL study
(Wiley, 2017)
info:eu-repo/semantics/article,
Objectives: Our aim was to determine the normative reference values of cardiorespiratory fitness (CRF) and to establish the proportion of subjects with low CRF suggestive of future cardio‐metabolic risk. Methods:
A total ...
Neuromuscular adaptations to combined strength and endurance training: order and time-of-day
(Thieme, 2017)
info:eu-repo/semantics/article,
The present study examined the effects of 24 weeks of morning vs. evening same-session combined strength (S) and endurance (E) training on neuromuscular and endurance performance. Fifty-one men were assigned to the morning ...
Effects of 10 min vs. 20 min passive rest after warm-up on 100 m freestyle time-trial performance: a randomized crossover study
(Elsevier, 2017)
info:eu-repo/semantics/article,
Objectives: The aim of this study was to compare the effect of 10 min vs. 20 min passive rest post warm-up on performance in a 100 m freestyle time-trial. Design: Randomized crossover. Methods: Eleven competitive male ...
PD1 signal transduction pathways in T cells
(Impact Journals, 2017)
Artículo / Artikulua,
The use of immune checkpoint inhibitors for the treatment of cancer is revolutionizing oncology. Amongst these therapeutic agents, antibodies that block PD-L1/PD1 interactions between cancer cells and T cells are demonstrating ...
Molecular mechanisms of programmed cell death-1 dependent T cell suppression: relevance for immunotherapy
(AME Publishing, 2017)
Artículo / Artikulua,
Programmed cell death-1 (PD1) has become a significant target for cancer immunotherapy. PD1 and its receptor programmed cell death 1 ligand 1 (PDL1) are key regulatory physiological immune checkpoints that maintain ...
PDL1 signals through conserved sequence motifs to overcome interferon-mediated cytotoxicity
(Elsevier, 2017)
Artículo / Artikulua,
PDL1 blockade produces remarkable clinical responses, thought to occur by T cell reactivation
through prevention of PDL1-PD1 T cell inhibitory interactions. Here, we find that PDL1 cell-intrinsic
signaling protects cancer ...
El deterioro funcional y la polifarmacia como predictoras de riesgo en el paciente mayor de 65 años en urgencias
(Grupo ENE de Investigación en Lenguajes Enfermeros, 2017)
Artículo / Artikulua,
Introducción y objetivo. El objetivo ha sido analizar la asociación entre el deterioro funcional y la polifarmacia del paciente anciano con la mortalidad, la frecuentación en urgencias y la hospitalización a corto plazo, ...