Listar Colecciones de Investigación y Producción Científica - Ikerketa eta ekoizpen zientifikoko Bildumak por autor UPNA "Reina Arias, Ramsés"
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Base genética del tropismo de lentivirus de pequeños rumiantes y estudio de la resistencia innata por APOBEC3
Glaría Ezquer, Idoia
(2015)
Tesis doctoral / Doktoretza tesia 
Los lentivirus de pequeños rumiantes (SRLV), que incluyen al virus Visna/Maedi (VMV) y al de la artritis encefalitis caprina (CAEV), infectan ovejas y cabras distribuidas por todo el mundo causando un cuadro multisistémico ... -
Characterization of ovine A3Z1 restriction properties against small ruminant lentiviruses (SRLVs)
Pablo Maiso, Lorena de 
; Glaría Ezquer, Idoia ; Crespo, Helena ; Nistal Villán, Estanislao; Andrésdóttir, Valgerdur; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz ; Reina Arias, Ramsés (MDPI, 2017)
Artículo / Artikulua
Intrinsic factors of the innate immune system include the apolipoprotein B editing enzyme catalytic polypeptide-like 3 (APOBEC3) protein family. APOBEC3 inhibits replication of different virus families by cytosine ... -
Detection of PrPSc in lung and mammary gland is favored by the presence of Visna/maedi virus lesions in naturally coinfected sheep
Salazar, Eider; Monleón, Eva; Bolea, Rosa; Acín, Cristina; Pérez, Marta María; Álvarez, Neila; Leginagoikoa, Iratxe; Juste, Ramón; Minguijón, Esmeralda; Reina Arias, Ramsés ; Glaría Ezquer, Idoia ; Berriatua, Eduardo; Andrés Cara, Damián de ; Badiola, Juan José; Amorena Zabalza, Beatriz ; Luján, Lluís (EDP Sciences, 2010)
Artículo / Artikulua
There are few reports on the pathogenesis of scrapie (Sc) and Visna/maedi virus (VMV) coinfections. The aim of this work was to study in vivo as well as post mortem both diseases in 91 sheep. Diagnosis of Sc and VMV ... -
Diagnosing infection with small ruminant lentiviruses of genotypes A and B by combining synthetic peptides in ELISA
Sanjosé, Leticia; Crespo, Helena; Glaría Ezquer, Idoia ; Andrés Cara, Damián de ; Reina Arias, Ramsés (Elsevier, 2015)
Artículo / Artikulua
The major challenges in diagnosing small ruminant lentivirus (SRLV) infection include early detection and genotyping of strains of epidemiological interest. A longitudinal study was carried out in Rasa Aragonesa sheep ... -
Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq
Bilbao Arribas, Martin; Abendaño, Naiara; Varela Martínez, Endika; Reina Arias, Ramsés ; Andrés Cara, Damián de ; Jugo, Begoña M. (BioMed Central, 2019)
Artículo / Artikulua
Background: MicroRNAs (miRNAs) are short endogenous, single-stranded, noncoding small RNA molecules of approximately 22 nucleotides in length. They regulate gene expression posttranscriptionally by silencing mRNA expression, ... -
Growth performance and clinicopathological analyses in lambs repetitively inoculated with aluminum-hydroxide containing vaccines or aluminum-hydroxide only
Miguel, Ricardo de; Asín, Javier; Rodríguez Largo, Ana; Echeverría Garín, Irache ; Lacasta, Delia; Andrés Cara, Damián de ; Reina Arias, Ramsés ; Pinczowski, Pedro; Gimeno, Marina; Molín, Jéssica; Fernández, Antonio; Blas, Ignacio de; Pérez, Marta María; Luján, Lluís (MDPI, 2021)
Artículo / Artikulua
Aluminum (Al) hydroxide is an effective adjuvant used in sheep vaccines. However, Al-adjuvants have been implicated as potential contributors to a severe wasting syndrome in sheep— the so-called ovine autoimmune-inflammatory ... -
Identificación de lentivirus de pequeños rumiantes en granulomas post-vacunales y evaluación de métodos de diagnóstico y selección genética en la lucha frente a la infección
Echeverría Garín, Irache (2021)
Tesis doctoral / Doktoretza tesia
Esta tesis plantea tres objetivos que se desarrollarán en tres capítulos independientes, correspondientes a sus respectivas publicaciones. Por un lado, se ha caracterizado la presencia y replicación de SRLV en macrófagos ... -
Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection
Crespo, Helena; Reina Arias, Ramsés ; Glaría Ezquer, Idoia ; Ramírez, Hugo ; Andrés, Ximena de; Jauregui, Paula; Luján, Lluís; Martínez Pomares, Luisa; Amorena Zabalza, Beatriz ; Andrés Cara, Damián de (BioMed Central, 2011)
Artículo / Artikulua
This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ... -
Immunization against small ruminant lentiviruses
Reina Arias, Ramsés ; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz (MDPI, 2013)
Artículo / Artikulua
Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered ... -
Innate immunity against small ruminant lentiviruses (SRLV): characterization of APOBEC3-derived restriction
Pablo Maiso, Lorena de (2020)
Tesis doctoral / Doktoretza tesia
En esta tesis se han llevado a cabo los siguientes estudios: 1. Identificación y caracterización de la restricción por APOBEC3 ovino frente a los SRLV. Se han estudiado dos tipos celulares que muestran restricción natural ... -
Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers
Salazar, Eider; Berriatua, Eduardo; Pérez, Marta María; Marín, Belén; Acín, Cristina; Martín Burriel, Inmaculada; Reina Arias, Ramsés ; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz ; Badiola, Juan José; Luján, Lluís (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)
Artículo / Artikulua
The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and ... -
Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit
Crespo, Helena; Guillén, Hugo; Pablo Maiso, Lorena de ; Gómez Arrebola, Carmen ; Rodríguez, Gregorio; Glaría Ezquer, Idoia ; Andrés Cara, Damián de ; Reina Arias, Ramsés (Taylor & Francis, 2017)
Artículo / Artikulua
β-glucans exhibited in cell walls of several pathogens as bacteria or fungi are sensed by pathogen recognition receptors such as scavenger receptors present in antigen presenting cells, i.e., macrophages. β-glucans obtained ... -
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
Crespo, Helena; Jauregui, Paula; Glaría Ezquer, Idoia ; Sanjosé, Leticia; Polledo, Laura; García Marín, Juan F.; Luján, Lluís; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz ; Reina Arias, Ramsés (BioMed Central, 2012)
Artículo / Artikulua
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ... -
Molecular signature of aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing
Varela Martínez, Endika; Abendaño, Naiara; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta María; Reina Arias, Ramsés ; Andrés Cara, Damián de ; Luján, Lluís; Jugo, Begoña M. (Frontiers Media, 2018)
Artículo / Artikulua
There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ... -
Multi-platform detection of small ruminant lentivirus antibodies and provirus as biomarkers of production losses
Echeverría Garín, Irache ; Miguel, Ricardo de; Pablo Maiso, Lorena de ; Glaría Ezquer, Idoia ; Benito, Alfredo A.; Blas, Ignacio de; Andrés Cara, Damián de ; Luján, Lluís; Reina Arias, Ramsés (Frontiers Media, 2020)
Artículo / Artikulua
Small ruminant lentiviruses (SRLVs) are endemic in most areas of Europe, causing a chronic infection and a multisystemic disease affecting the udder, carpal joints, lungs, and central nervous system. Due to the lack of ... -
Ovine TRIM5α can restrict visna/maedi virus
Jauregui, Paula; Crespo, Helena; Glaría Ezquer, Idoia ; Luján, Lluís; Contreras, A.; Rosati, Sergio; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz ; Towers, G. J.; Reina Arias, Ramsés (American Society for Microbiology, 2012)
Artículo / Artikulua
The restrictive properties of tripartite motif-containing 5 alpha (TRIM5α) from small ruminant species have not been explored. Here, we identify highly similar TRIM5α sequences in sheep and goats. Cells transduced with ... -
Post-entry blockade of small ruminant lentiviruses by wild ruminants
Sanjosé, Leticia; Crespo, Helena; Blatti-Cardinaux, Laure; Glaría Ezquer, Idoia ; Martínez Carrasco, Carlos; Berriatua, Eduardo; Amorena Zabalza, Beatriz ; Andrés Cara, Damián de ; Bertoni, Giuseppe; Reina Arias, Ramsés (BioMed Central, 2016)
Artículo / Artikulua
Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ... -
Replication of small ruminant lentiviruses in aluminum hydroxide-induced granulomas in sheep: a potential new factor for viral dissemination
Echeverría Garín, Irache ; Miguel, Ricardo de; Asín, Javier; Rodríguez Largo, Ana; Fernández, Antonio; Pérez, Marta María; Andrés Cara, Damián de ; Luján, Lluís; Reina Arias, Ramsés (American Society for Microbiology, 2021)
Artículo / Artikulua
Aluminum (Al)-based salts are widely used adjuvants in ruminants and other species to strengthen the immune response elicited against vaccine antigen(s). However, they can lead to the formation of long-lasting granulomas ... -
Sendai virus, a strong inducer of anti-lentiviral state in ovine cells
Pablo Maiso, Lorena de ; Echeverría Garín, Irache ; Rius-Rocabert, Sergio; Luján, Lluís; Garcin, Dominique; Andrés Cara, Damián de ; Nistal Villán, Estanislao; Reina Arias, Ramsés (MDPI, 2020)
Artículo / Artikulua
Small ruminant lentiviruses (SRLVs) are widely spread in the ovine and caprine populations, causing an incurable disease aecting animal health and production. Vaccine development is hindered owing to the high genetic ... -
Small ruminant lentiviruses: genetic variability, tropism and diagnosis
Ramírez, Hugo ; Reina Arias, Ramsés ; Amorena Zabalza, Beatriz ; Andrés Cara, Damián de ; Martínez, Humberto A. (MDPI, 2013)
Artículo / Artikulua
Small ruminant lentiviruses (SRLV) cause a multisystemic chronic disease affecting animal production and welfare. SRLV infections are spread across the world with the exception of Iceland. Success in controlling SRLV spread ...
