Listar Artículos de revista - Aldizkari artikuluak por autor UPNA "Lasa Uzcudun, Íñigo"

Mostrando ítems 41-58 de 58

    • RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria 

      Ferrer, María Desamparados; Quiles Puchalt, Nuria; Harwich, Michael D.; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Barbé, Jordi; Lasa Uzcudun, Íñigo Upna Orcid; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2011)   Artículo / Artikulua  OpenAccess
      Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...

    • The role of ArlRS and VraSR in regulating ceftaroline hypersusceptibility in methicillin-resistant Staphylococcus aureus 

      Villanueva San Martín, Maite Upna Orcid; Roch, Melanie; Lasa Uzcudun, Íñigo Upna Orcid; Renzoni, Adriana; Kelley, William L. (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Methicillin-resistant Staphylococcus aureus infections are a global health problem. New control strategies, including fifth-generation cephalosporins such as ceftaroline, have been developed, however rare sporadic resistance ...

    • Role of biofilm-associated protein bap in the pathogenesis of bovine Staphylococcus aureus 

      Cucarella, Carme; Tormo Más, María Ángeles; Ubeda, Carles; Trotonda, María Pilar; Monzon, Marta; Peris, Cristòfol; Amorena Zabalza, Beatriz Upna; Lasa Uzcudun, Íñigo Upna Orcid; Penadés, José R. (American Society for Microbiology, 2004)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus is a common cause of intramammary infections, which frequently become chronic, associated with the ability of the bacteria to produce biofilm. Here, we report a relationship between the ability to ...

    • Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer 

      Maiques, Elisa; Ubeda, Carles; Tormo Más, María Ángeles; Ferrer, María Desamparados; Lasa Uzcudun, Íñigo Upna Orcid; Novick, Richard P.; Penadés, José R. (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
      SaPIbov2 is a member of the SaPI family of staphylococcal pathogenicity islands and is very closely related to SaPIbov1. Typically, certain temperate phages can induce excision and replication of one or more of these islands ...

    • RsaI, un ARN régulateur aux multiples facettes, module le métabolisme du pathogène opportuniste Staphylococcus aureus 

      Desgranges, Emma; Bronesky, Delphine; Corvaglia, Anna; François, Patrice; Caballero Sánchez, Carlos Upna; Prado, Laura; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Moreau, Karen; Vandenesch, François; Marzi, Stefano; Romby, Pascale; Caldelari, Isabelle (EDP Sciences, 2019)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus est une bactérie commensale retrouvée chez environ 30 % des individus sains dont elle colonise la peau et la muqueuse nasale. Cependant, c’est également une bactérie pathogène opportuniste ...

    • Salmonella biofilm development depends on the phosphorylation status of RcsB 

      Latasa Osta, Cristina Upna; García Martínez, Begoña Upna Orcid; Echeverz Sarasúa, Maite Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...

    • SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development 

      Tormo Más, María Ángeles; Martí, Miguel; Valle Turrillas, Jaione Upna Orcid; Manna, Adhar C.; Cheung, Ambrose L.; Lasa Uzcudun, Íñigo Upna Orcid; Penadés, José R. (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      Staphylococcus epidermidis biofilm formation is associated with the production of the polysaccharide intercellular adhesin (PIA)--poly-N-acetylglucosamine polysaccharide (PNAG) by the products of the icaADBC operon. ...

    • SarA positively controls Bap-dependent biofilm formation in Staphylococcus aureus 

      Trotonda, María Pilar; Manna, Adhar C.; Cheung, Ambrose L.; Lasa Uzcudun, Íñigo Upna Orcid; Penadés, José R. (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      The biofilm-associated protein Bap is a staphylococcal surface protein involved in biofilm formation. We investigated the influence of the global regulatory locus sarA on bap expression and Bap-dependent biofilm formation ...

    • Sensory deprivation in Staphylococcus aureus 

      Villanueva San Martín, Maite Upna Orcid; García Martínez, Begoña Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Rapún Araiz, Beatriz Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna Orcid; Martí, Miguel; Penadés, José R.; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Springer Nature, 2018)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ...

    • Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals 

      Taglialegna, Agustina Upna; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Matthews, Steve; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
      Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...

    • Staphylococcus aureus develops an alternative, ica-independent biofilm in the absence of the arlRS two-component system 

      Toledo Arana, Alejandro Upna Orcid; Merino, Nekane Upna; Vergara Irigaray, Marta Upna; Débarbouillé, Michel; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      The biofilm formation capacity of Staphylococcus aureus clinical isolates is considered an important virulence factor for the establishment of chronic infections. Environmental conditions affect the biofilm formation capacity ...

    • Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins 

      Tormo Más, María Ángeles; Ferrer, María Desamparados; Maiques, Elisa; Ubeda, Carles; Selva, Laura; Lasa Uzcudun, Íñigo Upna Orcid; Calvete, Juan J.; Novick, Richard P.; Penadés, José R. (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus pathogenicity islands (SaPIs) have an intimate relationship with temperate staphylococcal phages. During phage growth, SaPIs are induced to replicate and are efficiently encapsidated into special small ...

    • Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch 

      Ma, Junfeng; Cheng, Xiang; Xu, Zhonghe; Zhang, Yikan; Valle Turrillas, Jaione Upna Orcid; Fan, Xianyang; Lasa Uzcudun, Íñigo Upna Orcid (EMBO Press, 2021)   Artículo / Artikulua  OpenAccess
      The Staphylococcal Bap proteins sense environmental signals (such as pH, [Ca2+]) to build amyloid scaffold biofilm matrices via unknown mechanisms. We here report the crystal structure of the aggregation-prone region of ...

    • A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria 

      Quiles Puchalt, Nuria; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Toledo Arana, Alejandro Upna Orcid; Monedero, Vicente; Lasa Uzcudun, Íñigo Upna Orcid; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2013)   Artículo / Artikulua  OpenAccess
      The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families ...

    • A systematic evaluation of the two-component systems network reveals that ArlRS is a key regulator of catheter colonization by Staphylococcus aureus 

      Burgui Erice, Saioa Upna Orcid; Gil Puig, Carmen Upna Orcid; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      Two-component systems (TCS) are modular signal transduction pathways that allow cells to adapt to prevailing environmental conditions by modifying cellular physiology. Staphylococcus aureus has 16 TCSs to adapt to the ...

    • Systematic reconstruction of the complete two-component sensorial network in staphylococcus aureus 

      Rapún Araiz, Beatriz Upna Orcid; Haag, Andreas F.; Gil Puig, Carmen Upna Orcid; Dorado Morales, Pedro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2020)   Artículo / Artikulua  OpenAccess
      In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different ...

    • Towards the identification of the common features of bacterial biofilm development 

      Lasa Uzcudun, Íñigo Upna Orcid (Sociedad Española de Microbiología, 2006)   Artículo / Artikulua  OpenAccess
      Los microorganismos pueden vivir y proliferar como células individuales que nadan libremente en el medio o crecer en comunidades multicelulares muy bien organizadas dentro de una matriz que ellas mismas han sintetizado y ...

    • Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray 

      Segura, Víctor; Toledo Arana, Alejandro Upna Orcid; Uzqueda, Maite; Lasa Uzcudun, Íñigo Upna Orcid; Muñoz Barrutia, Arrate (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: High-density oligonucleotide microarray is an appropriate technology for genomic analysis, and is particulary useful in the generation of transcriptional maps, ChIP-on-chip studies and re-sequencing of the ...
      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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