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Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
(Public Library of Science, 2016)
Artículo / Artikulua,
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
Bacterial biofilm functionalization through Bap amyloid engineering
(Springer Nature, 2022)
Artículo / Artikulua,
Biofilm engineering has emerged as a controllable way to fabricate living structures with programmable functionalities. The amyloidogenic proteins comprising the biofilms can be engineered to create self-assembling ...
Base pairing interaction between 5′- and 3′-UTRs controls icaR mRNA translation in Staphylococcus aureus
(Public Library of Science, 2013)
Artículo / Artikulua,
The presence of regulatory sequences in the 39 untranslated region (39-UTR) of eukaryotic mRNAs controlling RNA stability
and translation efficiency is widely recognized. In contrast, the relevance of 39-UTRs in bacterial ...
Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection
(American Society for Microbiology, 2014)
Artículo / Artikulua,
The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due
to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ...
Evaluation of surface microtopography engineered by direct laser interference for bacterial anti-biofouling
(2015)
Artículo / Artikulua,
Biofilm formation by bacterial pathogens on the surface of medical and industrial settings is a 25 serious health problem. Modification of the biomaterial surface topography is a promising 26 strategy to prevent bacterial ...
Antibiofilm activity of flavonoids on staphylococcal biofilms through targeting BAP amyloids
(Nature Research, 2020)
info:eu-repo/semantics/article,
The opportunistic pathogen Staphylococcus aureus is responsible for causing infections related to indwelling medical devices, where this pathogen is able to attach and form biofilms. The intrinsic properties given by the ...
Regulation of heterogenous lexA expression in staphylococcus aureus by an antisense RNA originating from transcriptional read-through upon natural mispairings in the sbrB intrinsic terminator
(MDPI, 2022)
Artículo / Artikulua,
Bacterial genomes are pervasively transcribed, generating a wide variety of antisense RNAs (asRNAs). Many of them originate from transcriptional read-through events (TREs) during the transcription termination process. ...
Near-infrared fluorescence imaging as an alternative to bioluminescent bacteria to monitor biomaterial-associated infections
(Elsevier, 2014)
info:eu-repo/semantics/article,
Biomaterial-associated infection is one of the most common complications related with the
implantation of any biomedical device. Several in vivo imaging platforms have emerged as
powerful diagnostic tools to longitudinally ...
Sensory deprivation in Staphylococcus aureus
(Springer Nature, 2018)
info:eu-repo/semantics/article,
Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16
TCSs, one of which (WalRK) is essential. Here we show ...