Open Access
Is the phenotype designation by PSP-MDS criteria stable throughout the disease course and consistent with tau distribution?
(Frontiers Media, 2022) Sánchez Ruiz de Gordoa, Javier; Zelaya Huerta, María Victoria; Tellechea-Aramburo, Paula; Acha Santamaría, Blanca; Roldán, Miren; López Molina, Carlos; Coca, Valle; Galbete Jiménez, Arkaitz; Mendióroz Iriarte, Maite; Erro Aguirre, María Elena; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
Introduction: the MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do not discriminate the phenotype diversity. Our purpose was to search for anatomopathological differences among PSP phenotypes resulting from the application of the MDS-PSP criteria comparing with the previous ones. Methods: thirty-four PSP cases from a single brain bank were retrospectively classified according to the criteria used by Respondek et al. in 2014 and the PSP-MDS criteria at 3 years (MDS-3y), 6 years (MDS-6y) and at the last clinical evaluation before death (MDS-last). Semiquantitative measurement of total, cortical and subcortical tau load was compared. For comparative analysis, PSP-Richardson syndrome and PSP postural instability were grouped (PSP-RS/PI) as well as the PSP atypical cortical phenotypes (PSP-Cx). Results: applying the Respondek's criteria, PSP phenotypes were distributed as follow: 55.9% PSP-RS/PI, 26.5% PSP-Cx, 11.8% PSP-Parkinsonism (PSP-P), and 5.9% PSP-Cerebellum. PSP-RS/PI and PSP-Cx had a higher total tau load than PSP-P; PSP-Cx showed a higher cortical tau load than PSP-RS/PI and PSP-P; and PSP-RS/PI had a higher subcortical tau load than PSP-P. Applying the MDS-3y, MDS-6y and MDS-last criteria; the PSP-RS/PI group increased (67.6, 70.6 and 70.6% respectively) whereas the PSP-Cx group decreased (8.8, and 8.8 and 11.8%). Then, only differences in total and subcortical tau burden between PSP-RS/PI and PSP-P were observed. Interpretation: after the retrospective application of the new MDS-PSP criteria, total and subcortical tau load is higher in PSP-RS/PI than in PSP-P whereas no other differences in tau load between phenotypes were found, as a consequence of the loss of phenotypic diversity.
Open Access
Application of the Sugeno integral in fuzzy rule-based classification
(Elsevier, 2024-09-27) Wieczynski, Jonata; Lucca, Giancarlo; Borges, Eduardo N.; Urío Larrea, Asier; López Molina, Carlos; Bustince Sola, Humberto; Pereira Dimuro, Graçaliz; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
Fuzzy Rule-Based Classification System (FRBCS) is a well-known technique to deal with classification problems. Recent studies have considered the usage of the Choquet integral and its generalizations (e.g.: 𝐶𝑇 -integral, 𝐶𝐹 - Integral and 𝐶𝐶-integral) to enhance the performance of such systems. Such fuzzy integrals were applied to the Fuzzy Reasoning Method (FRM) to aggregate the fired fuzzy rules when classifying new data. However, the Sugeno integral, another well-known aggregation operator, obtained good results in other applications, such as brain–computer interfaces. These facts led to the present study, in which we consider the Sugeno integral in classification problems. That is, the Sugeno integral is applied in the FRM of a widely used FRBCS, and its performance is analyzed over 33 different datasets from the literature, also considering different fuzzy measures. To show the efficiency of this new approach, the results obtained are also compared with previous studies that involved the application of different aggregation functions. Finally, we perform a statistical analysis of the application.
Open Access
From restricted equivalence functions on Ln to similarity measures between fuzzy multisets
(IEEE, 2023) Ferrero Jaurrieta, Mikel; Takáč, Zdenko; Rodríguez Martínez, Iosu; Marco Detchart, Cedric; Bernardini, Ángela; Fernández Fernández, Francisco Javier; López Molina, Carlos; Bustince Sola, Humberto; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
Restricted equivalence functions are well-known functions to compare two numbers in the interval between 0 and 1. Despite the numerous works studying the properties of restricted equivalence functions and their multiple applications as support for different similarity measures, an extension of these functions to an n-dimensional space is absent from the literature. In this paper, we present a novel contribution to the restricted equivalence function theory, allowing to compare multivalued elements. Specifically, we extend the notion of restricted equivalence functions from L to L n and present a new similarity construction on L n . Our proposal is tested in the context of color image anisotropic diffusion as an example of one of its many applications.
Open Access
Proyecto Agroinc: prevención del impacto ambiental de incendios provocados por cosechadoras
(Interempresas Media, 2022) Arazuri Garín, Silvia; Mangado Ederra, Jesús; López Maestresalas, Ainara; López Molina, Carlos; Angulo Muñoz, Blanca; Arnal Atarés, Pedro; Jarén Ceballos, Carmen; Ingeniería; Ingeniaritza; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika; Proyectos e Ingeniería Rural; Landa Ingeniaritza eta Proiektuak; Institute on Innovation and Sustainable Development in Food Chain - ISFOOD; Gobierno de Navarra / Nafarroako Gobernua
Las cosechadoras de cereales, por las condiciones ambientales en las que trabajan, alta temperatura y baja humedad, tanto ambiental como del producto que están cosechando, pueden provocar accidentalmente incendios durante la época de recolección. Los daños económicos y medioambientales que estos incendios suponen pueden ser muy importantes, ya que las condiciones de propagación del fuego son óptimas. Los principales objetivos de este proyecto han sido evaluar el impacto ambiental de los incendios producidos en Navarra en los últimos años y establecer una guía de buenas prácticas para su prevención.
Open Access
Evaluation of near-infrared hyperspectral imaging for the assessment of potato processing aptitude
(Frontiers Media, 2022) López Maestresalas, Ainara; López Molina, Carlos; Oliva Lobo, Gil Alfonso; Jarén Ceballos, Carmen; Ruiz de Galarreta, José Ignacio; Peraza Alemán, Carlos Miguel; Arazuri Garín, Silvia; Ingeniaritza; Estatistika, Informatika eta Matematika; Institute on Innovation and Sustainable Development in Food Chain - ISFOOD; Ingeniería; Estadística, Informática y Matemáticas
The potato (Solanum tuberosum L.) is the world's fifth most important staple food with high socioeconomic relevance. Several potato cultivars obtained by selection and crossbreeding are currently on the market. This diversity causes tubers to exhibit different behaviors depending on the processing to which they are subjected. Therefore, it is interesting to identify cultivars with specific characteristics that best suit consumer preferences. In this work, we present a method to classify potatoes according to their cooking or frying as crisps aptitude using NIR hyperspectral imaging (HIS) combined with a Partial Least Squares Discriminant Analysis (PLS-DA). Two classification approaches were used in this study. First, a classification model using the mean spectra of a dataset composed of 80 tubers belonging to 10 different cultivars. Then, a pixel-wise classification using all the pixels of each sample of a small subset of samples comprised of 30 tubers. Hyperspectral images were acquired using fresh-cut potato slices as sample material placed on a mobile platform of a hyperspectral system in the NIR range from 900 to 1,700 nm. After image processing, PLS-DA models were built using different pre-processing combinations. Excellent accuracy rates were obtained for the models developed using the mean spectra of all samples with 90% of tubers correctly classified in the external dataset. Pixel-wise classification models achieved lower accuracy rates between 66.62 and 71.97% in the external validation datasets. Moreover, a forward interval PLS (iPLS) method was used to build pixel-wise PLS-DA models reaching accuracies above 80 and 71% in cross-validation and external validation datasets, respectively. Best classification result was obtained using a subset of 100 wavelengths (20 intervals) with 71.86% of pixels correctly classified in the validation dataset. Classification maps were generated showing that false negative pixels were mainly located at the edges of the fresh-cut slices while false positive were principally distributed at the central pith, which has singular characteristics.
Open Access
Reduction of complexity using generators of pseudo-overlap and pseudo-grouping functions
(2024) Ferrero Jaurrieta, Mikel; Paiva, Rui; Cruz, Anderson; Bedregal, Benjamin; Zhang, Xiaohong; Takáč, Zdenko; López Molina, Carlos; Bustince Sola, Humberto; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
Overlap and grouping functions can be used to measure events in which we must consider either the maximum or the minimum lack of knowledge. The commutativity of overlap and grouping functions can be dropped out to introduce the notions of pseudo-overlap and pseudo-grouping functions, respectively. These functions can be applied in problems where distinct orders of their arguments yield different values, i.e., in non-symmetric contexts. Intending to reduce the complexity of pseudo-overlap and pseudo-grouping functions, we propose new construction methods for these functions from generalized concepts of additive and multiplicative generators. We investigate the isomorphism between these families of functions. Finally, we apply these functions in an illustrative problem using them in a time series prediction combined model using the IOWA operator to evidence that using these generators and functions implies better performance.
Embargo
Non-symmetric over-time pooling using pseudo-grouping functions for convolutional neural networks
(Elsevier, 2024-07-01) Ferrero Jaurrieta, Mikel; Paiva, Rui; Cruz, Anderson; Bedregal, Benjamin; Miguel Turullols, Laura de; Takáč, Zdenko; López Molina, Carlos; Bustince Sola, Humberto; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika; Institute of Smart Cities - ISC
Convolutional Neural Networks (CNNs) are a family of networks that have become state-of-the-art in several fields of artificial intelligence due to their ability to extract spatial features. In the context of natural language processing, they can be used to build text classification models based on textual features between words. These networks fuse local features to generate global features in their over-time pooling layers. These layers have been traditionally built using the maximum function or other symmetric functions such as the arithmetic mean. It is important to note that the order of input local features is significant (i.e. the symmetry is not an inherent characteristic of the model). While this characteristic is appropriate for image-oriented CNNs, where symmetry might make the network robust to image rigid transformations, it seems counter-productive for text processing, where the order of the words is certainly important. Our proposal is, hence, to use non-symmetric pooling operators to replace the maximum or average functions. Specifically, we propose to perform over-time pooling using pseudo-grouping functions, a family of non-symmetric aggregation operators that generalize the maximum function. We present a construction method for pseudo-grouping functions and apply different examples of this family to over-time pooling layers in text-oriented CNNs. Our proposal is tested on seven different models and six different datasets in the context of engineering applications, e.g. text classification. The results show an overall improvement of the models when using non-symmetric pseudo-grouping functions over the traditional pooling function.
Open Access
A framework for active contour initialization with application to liver segmentation in MRI
(Springer, 2022) Mir Torres, Arnau; Antunes dos Santos, Felipe; Fernández Fernández, Francisco Javier; López Molina, Carlos; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
Object segmentation is a prominent low-level task in image processing and computer vision. A technique of special relevance within segmentation algorithms is active contour modeling. An active contour is a closed contour on an image which can be evolved to progressively fit the silhouette of certain area or object. Active contours shall be initialized as a closed contour at some position of the image, further evolving to precisely fit to the silhouette of the object of interest. While the evolution of the contour has been deeply studied in literature [5, 11], the study of strategies to define the initial location of the contour is rather absent from it. Typically, such contour is created as a small closed curve around an inner position in the object. However, literature contains no general-purpose algorithms to determine those inner positions, or to quantify their fitness. In fact, such points are frequently set manually by human experts, hence turning the segmentation process into a semi-supervised one. In this work, we present a method to find inner points in relevant object using spatial-tonal fuzzy clustering. Our proposal intends to detect dominant clusters of bright pixels, which are further used to identify candidate points or regions around which active contours can be initialized.
Open Access
Fuzzy integrals for edge detection
(Springer, 2023) Marco Detchart, Cedric; Lucca, Giancarlo; Pereira Dimuro, Graçaliz; Da Cruz Asmus, Tiago; López Molina, Carlos; Borges, Eduardo N.; Rincón Arango, Jaime Andrés; Julian, Vicente; Bustince Sola, Humberto; Estadística, Informática y Matemáticas; Estatistika, Informatika eta Matematika
In this work, we compare different families of fuzzy integrals in the context of feature aggregation for edge detection. We analyze the behaviour of the Sugeno and Choquet integral and some of its generalizations. In addition, we study the influence of the fuzzy measure over the extracted image features. For testing purposes, we follow the Bezdek Breakdown Structure for edge detection and compare the different fuzzy integrals with some classical feature aggregation methods in the literature. The results of these experiments are analyzed and discussed in detail, providing insights into the strengths and weaknesses of each approach. The overall conclusion is that the configuration of the fuzzy measure does have a paramount effect on the results by the Sugeno integral, but also that satisfactory results can be obtained by sensibly tuning such parameter. The obtained results provide valuable guidance in choosing the appropriate family of fuzzy integrals and settings for specific applications. Overall, the proposed method shows promising results for edge detection and could be applied to other image-processing tasks.
Open Access
Exploring the potential of hyperspectral imaging to detect Esca disease complex in asymptomatic grapevine leaves
(Elsevier, 2022) Pérez Roncal, Claudia; Arazuri Garín, Silvia; López Molina, Carlos; Jarén Ceballos, Carmen; Santesteban García, Gonzaga; López Maestresalas, Ainara; Ingeniaritza; Estatistika, Informatika eta Matematika; Agronomia, Bioteknologia eta Elikadura; Institute on Innovation and Sustainable Development in Food Chain - ISFOOD; Ingeniería; Estadística, Informática y Matemáticas; Agronomía, Biotecnología y Alimentación; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
Precise and reliable identification of specific plant diseases is a challenge within precision agriculture nowadays. This is the case of esca, a complex grapevine trunk disease, that represents a major threat to modern viticulture as it is responsible for large economic losses annually. The lack of effective control strategies and the complexity of esca disease expression make essential the identification of affected plants, before symptoms become evident, for a better management of the vineyard. This study evaluated the suitability of a near-infrared hyperspectral imaging (HSI) system to detect esca disease in asymptomatic grapevine leaves of Tempranillo red-berried cultivar. For this, 72 leaves from an experimental vineyard, naturally infected with esca, were collected and scanned with a lab-scale HSI system in the 900-1700 nm spectral range. Then, effective image processing and multivariate analysis techniques were merged to develop pixel-based classification models for the distinction of healthy, asymptomatic and symptomatic leaves. Automatic and interval partial least squares variable selection methods were tested to identify the most relevant wavelengths for the detection of esca-affected vines using partial least squares discriminant analysis and different pre-processing techniques. Three-class and two-class classifiers were carried out to differentiate healthy, asymptomatic and symptomatic leaf pixels, and healthy from asymptomatic pixels, respectively. Both variable selection methods performed similarly, achieving good classification rates in the range of 82.77-97.17% in validation datasets for either three-class or two-class classifiers. The latter results demonstrated the capability of hyperspectral imaging to distinguish two groups of seemingly identical leaves (healthy and asymptomatic). These findings would ease the annual monitoring of disease incidence in the vineyard and, therefore, better crop management and decision making.