Open Access
Psychometric properties and normative data using item response theory approach for three neuropsychological tests in Waranka children population
(MDPI, 2025-02-15) Fierro Bósquez, María José; Fuentes Mendoza, Eliana María; Olabarrieta Landa, Laiene; Abiuso Lillo, Trinidad; Orozco Acosta, Erick; Mascialino, Guido; Arango Lasprilla, Juan Carlos; Rivera, Diego; Ciencias de la Salud; Osasun Zientziak
: Objective: To evaluate the psychometric properties of the Shortened Version of the Token Test (SVTT), the Peabody Picture Vocabulary Test (PPVT-III), and the Rey–Osterrieth Complex Figure (ROCF) using an item response theory (IRT) framework and to establish normative data for Waranka children and adolescents based on their ability scores. Methods: A total of 436 healthy people aged between 6 and 17 participated in this study. The factor structure was evaluated using confirmatory factor analysis (CFA) and the difficulty and discrimination parameters using IRT through the two-parameter logistic model for the SVTT and PPTV-III, while for the ROCF, the graded response model was used. The ordinal alpha and McDonald’s omega were used for reliability. Results: For most items, a low ability was enough to achieve the highest scores for the ROCF and SVTT. For the PPVTIII, the items aligned sequentially based on the difficulty, and a low level of ability was enough to achieve the highest score for the first 40 items. The ROCF, SVTT, and PPVTIII demonstrated adequate reliability. The ROCF copy and immediate recall scores were influenced by the mean parents’ years of education (MPE) and quadratic age interaction. The SVTT performance was affected by the quadratic age and sex interaction, and the PPVT-III by the interaction effect of the MPE and quadratic age. Conclusions: This is the first study to analyze the psychometric properties of the ROCF, SVTT, and PPVT-III through IRT models that are accurate and relevant for the validity of the obtained data and generate normative data in the under-represented nation of Ecuador for clinical and research purposes.
Open Access
15-item version of the Boston naming test: normative data for the Latin American spanish-speaking adult population.
(American Psychological Association, 2023) Del Cacho Tena, Ana María; Merced, Kritzia; Perrin, Paul B.; Arango Lasprilla, Juan Carlos; Olabarrieta Landa, Laiene; Rivera, Diego; Ciencias de la Salud; Osasun Zientziak
Objective: Naming is commonly impaired in people with neurodegenerative diseases and brain injury, and as a result, its accurate assessment is essential. The aim of this study was to provide normative data for the 15-item Spanish version of the Boston Naming Test (BNT) for an adult population from eight Latin American countries/regions. Method: The total sample consisted of 2,828 participants from Argentina, Chile, Cuba, El Salvador, Mexico, Honduras, Paraguay, and Puerto Rico. Multiple regressions were used to generate normative data following a four-step process. Results: Regression models showed a linear effect of age on the 15-item BNT total score for Argentina, Chile, Mexico, and Puerto Rico. In contrast, Paraguay showed a quadratic age effect. Almost all countries showed a positive linear effect of education, except Cuba which had a quadratic effect. Sex was a significant predictor in Argentina, Chile, Cuba, and Mexico, where in women scored lower than men. Conclusions: This study generates normative data for the 15-item Spanish version of the BNT and offers a free open-source calculator that will assist in the efficacious use of this neuropsychological test in clinical practice and research.
Open Access
Sexual functioning, desire, and satisfaction in women with TBI and healthy controls
(Hindawi, 2015) Strizzi, Jenna; Olabarrieta Landa, Laiene; Pappadis, Monique; Olivera, Silvia Leonor; Valdivia Tangarife, Edgar Ricardo; Fernandez Agis, Inmaculada; Perrin, Paul B.; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun Zientziak
Traumatic brain injury (TBI) can substantially alter many areas of a person’s life and there has been little research published regarding sexual functioning in women with TBI. Methods. A total of 58 women (29 with TBI and 29 healthy controls) from Neiva, Colombia, participated. There were no statistically significant differences between groups in sociodemographic characteristics. All 58 women completed the Sexual Quality of Life Questionnaire (SQoL), Female Sexual Functioning Index (FSFI), Sexual Desire Inventory (SDI), and the Sexual Satisfaction Index (ISS). Results. Women with TBI scored statistically significantly lower on the SQoL (𝑝 < 0.001), FSFI subscales of desire (𝑝 < 0.05), arousal (𝑝 < 0.05), lubrication (𝑝 < 0.05), orgasm (𝑝 < 0.05), and satisfaction (𝑝 < 0.05), and the ISS (𝑝 < 0.001) than healthy controls. Multiple linear regressions revealed that age was negatively associated with some sexuality measures, while months since the TBI incident were positively associated with these variables. Conclusion. These results disclose that women with TBI do not fare as well as controls in these measures of sexual functioning and were less sexually satisfied. Future research is required to further understand the impact of TBI on sexual function and satisfaction to inform for rehabilitation programs.
Embargo
Test of memory malingering 2nd edition: normative data from cognitively intact adults living in Spain
(Routledge, 2024-11-05) Arango Lasprilla, Juan Carlos; Ayearst, Lindsay E.; Rivera, Diego; Dini, Mia E.; Olabarrieta Landa, Laiene; Ramos Usuga, Daniela; Perrin, Paul B.; McCaffrey, Robert; Ciencias de la Salud; Osasun Zientziak
This study evaluated the universality of the TOMM 2 and provided a reference sample of cognitively intact adults living in Spain whose native language was Spanish. A total of 203 adults completed the TOMM 2 from June 2019 to January 2020. When using the original TOMM cutoff scores derived from English speakers, all participants scored in a range that would suggest that they passed the TOMM. When using a cut score less than 40 on Trial 1, only one participant in this study would be mistakenly classified as providing an invalid performance. Spanish-speaking adults in Spain from this study achieved a perfect score on Trial 1 at a rate more than double that of English-speaking individuals on the original TOMM. At the item level, all but one item met the minimum standard for performance validity; this item fell only marginally below the standard at 89%. This study found a very low failure rate for the TOMM 2, suggesting that the second edition has at least as high specificity as the original in Spanish adults.
Open Access
Executive function tests: normative data for Spanish-speaking adults in the United States
(2024-09-02) Ramos Usuga, Daniela; Rivera, Diego; Xia, Bridget; Carrión, Carmen I.; Morel Valdés, Gloria M.; Moreno, Oswaldo; Rodríguez, Miriam J.; Krch, Denise; Wongserbchart, Wongthipa; Drago, Christin I.; García, Patricia; Rivera, Patricia M.; Olabarrieta Landa, Laiene; Perrin, Paul B.; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun Zientziak
Background: normative data for Spanish-speaking populations, particularly Hispanics in the U.S., is notably scarce. Objective: This study aims to establish normative data for executive function tests (M-WCST, SCWT) among Spanish-speaking Hispanics in the U.S. Methods: we assessed 245 individuals aged 18-80 from eight U.S. states (California, Connecticut, Florida, Indiana, New Jersey, Oregon, Virginia, and Wisconsin) and employed Bayesian regression to estimate norms, considering various sociodemographic factors influencing performance. Results: age impacts SCWT scores negatively, especially in older individuals, with stronger effects among those proficient in Spanish. Age also affects M-WCST performance more in individuals with longer U.S. residency. Education correlates with M-WCST outcomes, with lower attainment linked to more errors. Education interacts with Spanish proficiency, influencing SCWT scores differently based on proficiency levels. Sex and acculturation levels interact, affecting SCWT performance differently between men and women. Conclusions: establishing culturally sensitive normative data can enhance accurate identification of executive dysfunction and reduce misdiagnosis risks. This underscores the importance of considering sociocultural factors including acculturation and language proficiency in neuropsychological assessments to better serve diverse populations.
Open Access
Methodology for the generation of normative data for the U.S. adult Spanish-speaking population: a Bayesian approach
(SAGE, 2024-09-20) Rivera, Diego; Forte, Anabel; Olabarrieta Landa, Laiene; Perrin, Paul B.; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun Zientziak
Objective: To present the methodology for a study generating normative neuropsychological test data for healthy Spanish-speaking adults (18-80 years old) living in the U.S. using Bayesian inference as a novel approach. Method: The study sample consisted of 253 healthy adults from eight U.S. regions (California, Connecticut, Florida, Indiana, New Jersey, Oregon, Virginia, and Wisconsin), with individuals originating from a diverse array of Latin American countries. To participate in the study, individuals must have met the following criteria: were between 18 and 80 years of age, had lived in the U.S. for at least 1 year (12 continuous months), self-identified Spanish as their dominant language, had at least one year of formal education, were able to read and write in Spanish at the time of evaluation, scored ¿23 on the Mini-Mental State Examination, scored <10 on the Patient Health Questionnaire¿9, and scored <10 on the Generalized Anxiety Disorder scale. Participants completed 12 neuropsychological tests. Reliability statistics and norms were calculated for all tests. Conclusions: This was the first normative study for Spanish-speaking adults in the U.S. to implement demographic, acculturation, and bilingual dominance measures as possible controls. Additionally, it was the first study to use Bayesian linear or generalized linear regression models for generating normative data in neuropsychology.
Open Access
Factor structure of the 10-item CES-D scale among patients with persistent COVID-19
(Wiley, 2022) Ramírez Vélez, Robinson; Olabarrieta Landa, Laiene; Rivera, Diego; Izquierdo Redín, Mikel; Ciencias de la Salud; Osasun Zientziak; Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa
The presence of persistent coronavirus disease 2019 (COVID-19) might beassociated with significant levels of psychological distress that would meet thethreshold for clinical relevance. The Center for Epidemiologic Studies DepressionScale (CES-D) version 10 has been widely used in assessing psychological distressamong general and clinical populations from different cultural backgrounds. To ourknowledge, however, researchers have not yet validated these findings amongpatients with persistent COVID-19. A cross-sectional validation study wasconducted with 100 patients from the EXER-COVID project (69.8% women;mean (±standard deviation) ages: 47.4 ± 9.5 years). Confirmatory factor analyses(CFAs) were performed on the 10-item CES-D to test four model fits: (a)unidimensional model, (b) two-factor correlated model, (c) three-factor correlatedmodel, and (d) second-order factor model. The diagonal-weighted least-squares estimator was used, as it is commonly applied to latent variable modelswith ordered categorical variables. The reliability indices of the 10-item CES-D in patients with persistent COVID-19 were as follows: depressive affect factor(α=0.82Ord;ω=0.78u−cat), somatic retardation factor (α=0.78Ord;ω=0.56u−cat),and positive affect factor (α=0.56Ord;ω=0.55u−cat). The second‐order model fitshowed good Omega reliability (ω=0.87ho). Regarding CFAs, the unidimensional‐factor model shows poor goodness of fit, especially residuals analysis (root meansquare error of approximation [RMSEA] = 0.081 [95% confidence interval,CI = 0.040–0.119]; standardized root mean square residual [SRMR] = 0.101). The two‐factor correlated model, three‐factor correlated model, and second‐order factormodel showed adequate goodness of fit, and theχ2difference test (∆X2) did not show significant differences between the goodness of fit for these models(∆X= 4.11282;p= 0.127). Several indices showed a good fit with the three‐factor correlated model: goodness‐of‐fit index = 0.974, comparative fit index = 0.990,relative noncentrality index = 0.990, and incremental fit index = 0.990, which were all above 0.95, the traditional cut‐off establishing adequate fit. On the other hand RMSEA = 0.049 (95% CI = 0.000–0.095), where an RMSEA < 0.06–0.08 indicates anadequate fit. Item loadings on the factors were statistically significant (λ≥0.449j;p's < 0.001), indicating that the items loaded correctly on the corresponding factors and the relationship between factors (φ≥0.382;p's≤0.001. To our knowledge, thisis the first study to provide validity and reliability to 10‐item CES‐D in a persistentCOVID‐19 Spanish patient sample. The validation and reliability of this shortscreening tool allow us to increase the chance of obtaining complete data in aparticular patient profile with increased fatigue and brain fog that limit patients' capacity to complete questionnaires.
Open Access
Treatment effectiveness for male intimate partner violence perpetrators depending on problematic alcohol use
(Elsevier, 2022) Siria Mendaza, Sandra; Fernández-Montalvo, Javier; Echauri, José Antonio; Azkárate, Juana; Martínez, María; Olabarrieta Landa, Laiene; Rivera, Diego; Ciencias de la Salud; Osasun Zientziak
Background: Problematic alcohol use (PAU) is highly correlated with intimate partner violence perpetration (IPV). However, when treatments for male IPV perpetrators that address alcohol consumption are evaluated, the results are varied. Therefore, the main goal of this study was to assess the differential long-term effectiveness of a standard individual treatment programme for male IPV perpetrators depending on the presence of PAU. Methods: The sample was composed of 641 male IPV perpetrators who completed a specialized individual treatment programme for gender violence perpetrators. All of the participants were followed for one year after treatment completion. Results: The effects of PAU on treatment success were evaluated by means of multiple logistic regression analyses. The full model was reliable (χ2 = 10.243; df = 3; p = .016), and overall, 88.8% of the predictions were accurate. The findings indicated that the probability of successful treatment does not depend on the presence of PAU. Conclusions: The relationship between IPV perpetration and PAU is highly complex, and several underlying mechanisms should be further evaluated. Accordingly, interventions should not only screen for alcohol consumption but also for all individual characteristics that might necessitate tailored treatment.
Open Access
Moderate, little, or no improvements in neurobehavioral symptoms among individuals with long COVID: A 34-country retrospective study
(MDPI, 2022) Ramos Usuga, Daniela; Perrin, Paul B.; Bogdanova, Yelena; Olabarrieta Landa, Laiene; Alzueta, Elisabet; Baker, Fiona C.; Iacovides, Stella; Cortes, Mar; Arango Lasprilla, Juan Carlos; Ciencias de la Salud; Osasun Zientziak
(1) Background: Some people with COVID-19 develop a series of symptoms that last for several months after infection, known as Long COVID. Although these symptoms interfere with people’s daily functioning and quality of life, few studies have focused on neurobehavioral symptoms and the risk factors associated with their development; (2) Methods: 1001 adults from 34 countries who had previously tested positive for COVID-19 completed the Neurobehavioral Symptom Inventory reporting the symptoms before their COVID-19 diagnosis, during the COVID-19 infection, and currently; (3) Results: Participants reported large-sized increases before vs. during COVID-19 in all domains. Participants reported a medium-sized improvement (during COVID-19 vs. now) in somatic symptoms, a small-sized improvement in affective symptoms, and very minor/no improvement in cognitive symptoms. The risk factors for increased neurobehavioral symptoms were: being female/trans, unemployed, younger age, low education, having another chronic health condition, greater COVID-19 severity, greater number of days since the COVID-19 diagnosis, not having received oxygen therapy, and having been hospitalized. Additionally, participants from North America, Europe, and Central Asia reported higher levels of symptoms across all domains relative to Latin America and Sub-Saharan Africa; (4) Conclusions: The results highlight the importance of evaluating and treating neurobehavioral symptoms after COVID-19, especially targeting the higher-risk groups identified. General rehabilitation strategies and evidence-based cognitive rehabilitation are needed in both the acute and Long COVID phases.
Open Access
A multidimensional approach to assessing factors impacting health-related quality of life after pediatric traumatic brain injury
(MDPI, 2023) Steinbuechel, Nicole von; Krenz, Ugne; Bockhop, Fabian; Koerte, Inga; Timmermann, Dagmar; Cunitz, Katrin; Zeldovich, Marina; Andelic, Nada; Rojczyk, Philine; Bonfert, Michaela Veronika; Berweck, Steffen; Kieslich, Matthias; Brockmann, Knut; Roediger, Maike; Lendt, Michael; Buchheim, Anna; Muehlan, Holger; Holloway, Ivana; Olabarrieta Landa, Laiene; Ciencias de la Salud; Osasun Zientziak
In the field of pediatric traumatic brain injury (TBI), relationships between pre-injury and injury-related characteristics and post-TBI outcomes (functional recovery, post-concussion depression, anxiety) and their impact on disease-specific health-related quality of life (HRQoL) are under-investigated. Here, a multidimensional conceptual model was tested using a structural equation model (SEM). The final SEM evaluates the associations between these four latent variables. We retrospectively investigated 152 children (8–12 years) and 148 adolescents (13–17 years) after TBI at the recruiting clinics or online. The final SEM displayed a fair goodness-of-fit (SRMR = 0.09, RMSEA = 0.08 with 90% CI [0.068, 0.085], GFI = 0.87, CFI = 0.83), explaining 39% of the variance across the four latent variables and 45% of the variance in HRQoL in particular. The relationships between pre-injury and post-injury outcomes and between post-injury outcomes and TBI-specific HRQoL were moderately strong. Especially, pre-injury characteristics (children’s age, sensory, cognitive, or physical impairments, neurological and chronic diseases, and parental education) may aggravate post-injury outcomes, which in turn may influence TBI-specific HRQoL negatively. Thus, the SEM comprises potential risk factors for developing negative post-injury outcomes, impacting TBI-specific HRQoL. Our findings may assist healthcare providers and parents in the management, therapy, rehabilitation, and care of pediatric individuals after TBI.