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Diverse methods with stereoselective induction in the asymmetric Biginelli reaction

dc.contributor.authorDíaz Fernández, Marcos
dc.contributor.authorAlgarra González, Manuel
dc.contributor.authorCalvo Losada, Saturnino
dc.contributor.authorQuirante, José Joaquín
dc.contributor.authorSarabia, Francisco
dc.contributor.authorPino-González, María Soledad
dc.contributor.departmentInstitute for Advanced Materials and Mathematics - INAMAT2en
dc.date.accessioned2024-10-03T11:37:49Z
dc.date.available2024-10-03T11:37:49Z
dc.date.issued2024-08-15
dc.date.updated2024-10-03T11:34:02Z
dc.description.abstractThe relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric synthetic advances in the formation of dihydropyrimidinones (DHPMs), dihydropyrimidinethiones (DHPMTs), and related compounds. The relevant bibliography on general processes in the Biginelli reaction and some methods of separation of isomers have also been referenced.en
dc.description.sponsorshipFinancial support has been received from the Spanish Ministry of Science and Innovation RTI2018-098296-BI00 (MINECO and FEDER), and M. Algarra would like to thank the Ministry of Science and Innovation (MCIN/AEI/https://doi.org/10.13039/501100011033) for their support under the grant number PID2021-122613OB-I00
dc.format.mimetypeapplication/pdf
dc.identifier.citationDíaz-Fernández, M., Algarra, M., Calvo-Losada, S., Quirante, J. J., Sarabia, F., Pino-González, M. S. (2024) Diverse methods with stereoselective induction in the asymmetric Biginelli reaction. Molecules, 29(16), 1-20. https://doi.org/10.3390/molecules29163864
dc.identifier.doi10.3390/molecules29163864
dc.identifier.issn1420-3049
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/51961
dc.language.isoeng
dc.publisherMDPI Publishing
dc.relation.ispartofMolecules, 29(16), 1-20
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-098296-BI00
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2021-122613OB-I00/ES/
dc.relation.publisherversionhttps://doi.org/10.3390/molecules29163864
dc.rights© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectPyrimidinesen
dc.subjectMulticomponent reactionsen
dc.subjectAsymmetricen
dc.subjectEnantioselectiveen
dc.subjectN-heterocyclesen
dc.subjectBiginelli reactionen
dc.titleDiverse methods with stereoselective induction in the asymmetric Biginelli reactionen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication
relation.isAuthorOfPublicationac68d8d5-2b22-478e-878b-bb0893409ddf
relation.isAuthorOfPublication.latestForDiscoveryac68d8d5-2b22-478e-878b-bb0893409ddf

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