Obesity-and lipid-related parameters in the identification of older adults with a high risk of prediabetes according to the American diabetes association: an analysis of the 2015 health, well-being, and aging study

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dc.contributor.authorRamírez Vélez, Robinson
dc.contributor.authorPérez Sousa, Miguel A.
dc.contributor.authorGonzález Ruiz, Katherine
dc.contributor.authorCano Gutiérrez, Carlos Alberto
dc.contributor.authorSchmidt Río-Valle, Jacqueline
dc.contributor.authorCorrea Rodríguez, María
dc.contributor.authorIzquierdo Redín, Mikel
dc.contributor.authorRomero García, Jesús Astolfo
dc.contributor.authorCampos Rodríguez, Adriana Yolanda
dc.contributor.authorTriana Reina, Héctor Reynaldo
dc.contributor.authorGonzález Jiménez, Emilio
dc.contributor.departmentCiencias de la Saludes_ES
dc.contributor.departmentOsasun Zientziakeu
dc.date.accessioned2020-05-19T06:57:55Z
dc.date.available2020-05-19T06:57:55Z
dc.date.issued2019
dc.description.abstractThis study evaluated the predictive ability of 11 obesity-and lipid-related parameters, including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WtHR), body roundness index (BRI), 'A' body-shape index (ABSI), conicity index (CI), visceral adiposity index (VAI), triglyceride-to-glucose fasting index (TyG), triglyceride-to-glucose fasting related to BMI (TyG-BMI), triglyceride-to-glucose fasting related to WC (TyG-WC), and triglyceride-to-glucose fasting related to WtHR (TyG-WtHR), to identify patients from an elderly Colombian population with a high risk of prediabetes according to the 2016 American Diabetes Association criteria. The data were obtained from the 2015 Colombian Health and Wellbeing and Aging Survey. A total of 3307 elderly Colombian individuals (aged over 60 years) were included. Anthropometric data, fasting plasma glucose, blood lipid profiles, family history, and health-related behaviors were assessed, and prediabetes was defined as a fasting plasma glucose of 100 to 125 mg/dL. The areas under the receiver operating characteristic (ROC) curves (AUCs) were calculated for each anthropometric indicator, using the prediabetes classification to identify their sensitivity and specificity, and these indicated that the prevalence of prediabetes was 25.3% in this population. After adjusting for potential confounding factors, the TyG index was strongly associated with the odds of having prediabetes in both sexes, and multivariate logistic regression analysis showed that the ORs for prediabetes increased across quartiles (p < 0.001). The TyG index was best able to identify prediabetes in either sex (AUC and optimal cut-off = 0.700 and 8.72, and 0.695 and 8.92 for men and women, respectively), suggesting that compared to the other parameters, the TyG index has the best discriminative power to predict prediabetes in the whole population. Thus, we propose the TyG index be used as a complementary marker for assessing prediabetes in older adults.en
dc.description.sponsorshipThis study is part of a larger project that has been funded by a Colciencias y Ministerio de Salud y la Protección Social de Colombia (The SABE Study ID 2013, no. 764). Mikel Izquierdo is funded in part by a research grant PI17/01814 of the Ministerio de Economía, Industria y Competitividad (ISCIII, FEDER).en
dc.format.extent21 p.
dc.format.mimetypeapplication/pdfen
dc.identifier.doi10.3390/nu11112654
dc.identifier.issn2072-6643
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/36913
dc.language.isoengen
dc.publisherMDPIen
dc.relation.ispartofNutrients, 2019, 11 (11), 2654en
dc.relation.publisherversionhttps://doi.org/10.3390/nu11112654
dc.rights© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY)en
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAdiposityen
dc.subjectPrediabetesen
dc.subjectLipidsen
dc.subjectAnthropometric measureen
dc.subjectElderlyen
dc.titleObesity-and lipid-related parameters in the identification of older adults with a high risk of prediabetes according to the American diabetes association: an analysis of the 2015 health, well-being, and aging studyen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication
relation.isAuthorOfPublicationd0c2c11e-01d0-46ff-93b4-36b11beaf269
relation.isAuthorOfPublicationef73585d-4750-4f56-9d4f-0d759232dbca
relation.isAuthorOfPublication.latestForDiscoveryd0c2c11e-01d0-46ff-93b4-36b11beaf269

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