Quality of life of male breast cancer survivors: a systematic review

dc.contributor.authorLópez Wilson, Arleen
dc.contributor.authorLeite, Ana Carolina Andrade Biaggi
dc.contributor.authorSoto Ruiz, María Nelia
dc.contributor.authorEscalada Hernández, Paula
dc.contributor.authorGarcía Vivar, Cristina
dc.contributor.departmentCiencias de la Saludes-ES
dc.contributor.departmentOsasun Zientziakeu
dc.date.accessioned2025-06-24T15:08:10Z
dc.date.available2025-06-24T15:08:10Z
dc.date.issued2025-04-30
dc.date.updated2025-06-24T14:33:23Z
dc.description.abstractIntroduction: Breast cancer treatments signifcantly infuence the quality of life of cancer survivors. While most studies havefocused on female breast cancer survivors, data on the quality of life of men who have undergone medical, surgical or radiologicaltreatments for breast cancer are limited. Objective: To evaluate the quality of life of male breast cancer survivors. Methods: A systematic review was conducted according to the PRISMA statement with a search in four databases: PubMed,Embase, Cochrane and Web of Science. We screened and extracted data and assessed the methodological quality of the studies viathe Cochrane RoB-2 and ROBINS-I tools for randomised clinical trials and follow-up studies, respectively. Te data werepresented in a narrative synthesis format. Results: In total, 993 records were identifed, of which three studies were included for analysis: two randomised clinical trials andone cohort study. Te interventions in the randomised clinical trials involved evaluating the impact of endocrine therapy and theimplementation of online physical training. Although there was a reduction in the overall quality of life during cancer treatment,patients who received tamoxifen monotherapy did not report a clinically signifcant change in their sexual function. Additionally,moderate exercise was shown to improve physical health and enhance social well-being. In the cohort study, quality of life andsymptom burden were evaluated in men with breast cancer treated with endocrine therapies at the time of diagnosis via symptomassessment scales. Conclusions: Male breast cancer survivors experience a decrease in quality of life during and after treatment. While tamoxifenmonotherapy preserves sexual function, moderate-intensity physical rehabilitation signifcantly improves both quality of life andsocial functioning. Te limited number of studies included in this review highlights the need for further research to address thephysical, psychological and social needs of male breast cancer survivors.en
dc.description.sponsorshipThis work was supported by the Carolina Foundation [Graduate Scholarships 2023, Spain].
dc.format.mimetypeapplication/pdf
dc.identifier.citationLópez Wilson, A., Leite, A. C. A. B., Soto-Ruiz, N., Escalada-Hernández, P., García-Vivar, C. (2025) Quality of life of male breast cancer survivors: a systematic review. European Journal of Cancer Care, 2025(1), 1-11. https://doi.org/10.1155/ecc/6941281.
dc.identifier.doi10.1155/ecc/6941281
dc.identifier.issn0961-5423
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/54307
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofEuropean Journal of Cancer Care 2025(1), 1-11
dc.relation.publisherversionhttps://doi.org/10.1155/ecc/6941281
dc.rights© 2025 Arleen López Wilson et al. European Journal of Cancer Care published by John Wiley & Sons Ltd. Tis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution andreproduction in any medium, provided the original work is properly cited.
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCancer survivorsen
dc.subjectChemotherapyen
dc.subjectImmunotherapyen
dc.subjectMale breast canceren
dc.subjectMastectomyen
dc.subjectQuality of lifeen
dc.subjectRadiotherapyen
dc.subjectSystematic reviewen
dc.subjectTamoxifenen
dc.titleQuality of life of male breast cancer survivors: a systematic reviewen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery90fe0c7a-2ad8-46ec-9bbf-b939a93ec431

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