Publication:
Ideal cardiovascular health and incident cardiovascular disease among adults: a systematic review and meta-analysis

Date

2018

Authors

Saavedra, José M.
Lobelo, Felipe
Celis Morales, Carlos
Pozo Cruz, Borja del
García Hermoso, Antonio

Director

Publisher

Mayo Foundation
Acceso abierto / Sarbide irekia
Artículo / Artikulua
Versión aceptada / Onetsi den bertsioa

Project identifier

Abstract

Objective: To investigate the association between ideal cardiovascular health (CVH) metrics and incident cardiovascular disease (CVD) by conducting a systematic review and meta-analysis of prospective cohort studies. Methods: The MEDLINE, EMBASE, and CINAHL databases were searched from January 1, 2010, through July 31, 2017, for studies that met the following criteria: (1) prospective studies conducted in adults, (2) with outcome data on CVD incidence and (3) a measure of ideal CVH metrics. Results: Twelve studies (210,443 adults) were included in this analysis. Compared with adults who met 0 to 2 of the ideal CVH metrics (high-risk individuals), a significantly lower hazard for CVD incidence was observed in those who had 3 to 4 points for the ideal CVH metrics (hazard ratio [HR]=0.53; 95% CI, 0.47-0.59) and 5 to 7 points (HR=0.28; 95% CI, 0.23-0.33). Weaker associations were observed in studies with older individuals, suggesting that there is a positive relationship between age and HR. Conclusion: Although meeting 5 to 7 metrics is associated with the lowest hazard for CVD incidence, meeting 3 to 4 metrics still offers an important protective effect for CVD. Therefore, a realistic goal in the general population in the short term could be to promote at least an intermediate ideal CVH profile (3 to 4 metrics).

Description

Keywords

Risk factors, Health behaviors, Life's Simple 7, Stroke, Cardiac prevention

Department

Ciencias de la Salud / Osasun Zientziak

Faculty/School

Degree

Doctorate program

item.page.cita

Ramírez-Vélez, R., Saavedra, J. M., Lobelo, F., Celis-Morales, C. A., Del Pozo-Cruz, B., García-Hermoso, A. (2018) Ideal cardiovascular health and incident cardiovascular disease among adults: a systematic review and meta-analysis. Mayo Clinic Proceedings, 93(11), 1589-1599. https://doi.org/10.1016/j.mayocp.2018.05.035

item.page.rights

© 2018 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0

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