The network and dimensionality structure of affective psychoses: an exploratory graph analysis approach

Peralta Martín, Víctor; Gil Berrozpe, Gustavo José; Sánchez Torres, Ana María; Cuesta, Manuel J.

The network and dimensionality structure of affective psychoses: an exploratory graph analysis approach

dc.contributor.author	Peralta Martín, Víctor
dc.contributor.author	Gil Berrozpe, Gustavo José
dc.contributor.author	Sánchez Torres, Ana María
dc.contributor.author	Cuesta, Manuel J.
dc.contributor.department	Ciencias de la Salud	es_ES
dc.contributor.department	Osasun Zientziak	eu
dc.contributor.funder	Gobierno de Navarra / Nafarroako Gobernua
dc.date.accessioned	2025-08-07T15:43:55Z
dc.date.available	2025-08-07T15:43:55Z
dc.date.issued	2020-12-01
dc.date.updated	2025-08-07T15:30:56Z
dc.description.abstract	Background: The dimensional symptom structure of classes of affective psychoses, and more specifically the relationships between affective and mood symptoms, has been poorly researched. Here, we examined these questions from a network analysis perspective. Methods: Using Exploratory Graph Analysis (EGA) and network centrality parameters, we examined the dimensionality and network structure of 28 mood and psychotic symptoms in subjects diagnosed with schizoaffective disorder (n=124), psychotic bipolar disorder (n=345) or psychotic depression (n=245), such as in the global sample of affective psychoses. Results: EGA identified four dimensions in subjects with schizoaffective or bipolar disorders (depression, mania, positive and negative) and three dimensions in subjects with psychotic depression (depression, psychosis and activation). The item composition of dimensions and the most central symptoms varied substantially across diagnoses. The most central (i.e., interconnected) symptoms in schizoaffective disorder, psychotic bipolar disorder and psychotic depression were hallucinations, delusions and depressive mood, respectively. Classes of affective psychoses significantly differed in terms of network structure but not in network global strength. Limitations: The cross-sectional nature of this study precludes conclusions about the causal dynamics between affective and psychotic symptoms. Conclusion: EGA is a powerful tool for examining the dimensionality and network structure of symptoms in affective psychoses showing that both the interconnectivity pattern between affective and psychotic symptoms and the most central symptoms vary across classes of affective psychoses. The findings outline the value of specific diagnoses in explaining the relationships between mood and affective symptoms.	en
dc.description.sponsorship	The study was funded by the Carlos III Health Institute (FEDER Funds) from the Spanish Ministry of Economy and Competitiveness (grant number PI16/02148) and the Regional Government of Navarra (grant number 31/17).
dc.format.mimetype	application/pdf
dc.format.mimetype	application/msword
dc.identifier.citation	Peralta, V., Gil-Berrozpe, G. J., Sánchez-Torres, A., Cuesta, M. J. (2020) The network and dimensionality structure of affective psychoses: an exploratory graph analysis approach. Journal of Affective Disorders, 277, 182-191. https://doi.org/10.1016/j.jad.2020.08.008.
dc.identifier.doi	10.1016/j.jad.2020.08.008
dc.identifier.issn	0165-0327
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/54632
dc.language.iso	eng
dc.publisher	Elsevier
dc.relation.ispartof	Journal of Affective Disorders 277, 2020, 182-191
dc.relation.projectID	info:eu-repo/grantAgreement/MINECO//PI16%2F02148/ES/
dc.relation.projectID	info:eu-repo/grantAgreement/Gobierno de Navarra///
dc.relation.publisherversion	https://doi.org/10.1016/j.jad.2020.08.008
dc.rights	© 2020 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject	Network analysis	en
dc.subject	Network structure	en
dc.subject	Factor analysis	en
dc.subject	Dimensionality	en
dc.subject	Affective psychoses	en
dc.subject	Symptom connectivity	en
dc.title	The network and dimensionality structure of affective psychoses: an exploratory graph analysis approach	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/acceptedVersion
dspace.entity.type	Publication
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