Reference values for handgrip strength and their association with intrinsic capacity domains among older adults
| dc.contributor.author | Ramírez Vélez, Robinson | |
| dc.contributor.author | Correa Bautista, Jorge Enrique | |
| dc.contributor.author | García Hermoso, Antonio | |
| dc.contributor.author | Cano Gutiérrez, Carlos Alberto | |
| dc.contributor.author | Izquierdo Redín, Mikel | |
| dc.contributor.department | Ciencias de la Salud | es_ES |
| dc.contributor.department | Osasun Zientziak | eu |
| dc.date.accessioned | 2019-11-25T13:16:02Z | |
| dc.date.available | 2019-11-25T13:16:02Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Objective The purposes of this study were three-fold: (i) to describe handgrip strength in older individuals aged >= 60 years in Colombia; (ii) to identify sex-specific and age-specific muscle weakness cut-off points in older adults; and (iii) to determine the odds of adverse events for each of the intrinsic capacity domains for individuals with handgrip strength greater than the muscle weakness cut-off points, as compared with their weaker counterparts. Methods A cross-sectional study was conducted in Colombia, among 5237 older adults aged >= 60 years old (58.5% women, 70.5 +/- 7.8 years), according to 'SABE Survey 2015'. Handgrip strength data were obtained with a Takei dynamometer. Sociodemographic variables, five domains of intrinsic capacity (i.e. locomotion, vitality, cognition, psychological, and sensory), and medical conditions were assessed and analyzed. Adjustments variables were age, ethnicity, socio-economic status, urbanicity, body mass index, smoking status, alcohol intake, drug use, physical activity, and co-morbid chronic diseases. Sex-stratified analyses were conducted with logistic regression models. Results Handgrip strength was greater among men than among women (26.7 +/- 8.5 vs. 16.7 +/- 5.7 kg, respectively, P < 0.001) at all ages. Weak handgrip strength cut-off points ranged from 17.4 to 8.6 and from 10.1 to 4.9 in men and women, respectively. Overall, participants with optimal handgrip strength had better intrinsic capacity [in men, odds ratio (OR) = 0.62, 95% confidence interval (CI) 0.53 to 0.71; P < 0.001; and in women, OR = 0.79, 95% CI 0.68 to 0.92; P = 0.002] than their weaker counterparts. Also, men with optimal handgrip strength had a lower risk of hospitalization (OR = 0.47, 95% CI 0.29 to 0.78; P = 0.004) than their weaker counterparts. Conclusions This study is the first to describe handgrip strength values and cut-off points for muscle weakness among a nationally representative sample of Colombian older adults by age and sex. After categorizing older adults as weak or not weak based on the handgrip cut-off points, non-weakness was associated with a decreased odds of intrinsic capacity impairments. These cut-off points may be good candidates for clinical assessment of risks to physical and mental health in older Colombian adults. | en |
| dc.description.sponsorship | The SABE study is supported by a fund (2013, no. 764) from the Colciencias y Ministerio de Salud y la Protección Social de Colombia. Mikel Izquierdo is funded by ISCIII and Fondos FEDER (PI17/01814). | en |
| dc.format.extent | 9 p. | |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.doi | 10.1002/jcsm.12373 | |
| dc.identifier.issn | 2190-5991 | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/35457 | |
| dc.language.iso | eng | en |
| dc.publisher | Wiley | en |
| dc.relation.ispartof | Journal of Cachexia Sarcopenia and Muscle, 2019, 10: 278-286 | en |
| dc.relation.publisherversion | https://doi.org/10.1002/jcsm.12373 | |
| dc.rights | © 2019 The Authors. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | en |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Skeletal muscle | en |
| dc.subject | Handgrip | en |
| dc.subject | Older adults | en |
| dc.subject | Locomotion | en |
| dc.subject | Vitality | en |
| dc.subject | Cognition | en |
| dc.subject | Mental health | en |
| dc.title | Reference values for handgrip strength and their association with intrinsic capacity domains among older adults | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication | |
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