Publication:
Effects of exercise in addition to a family-based lifestyle intervention program on hepatic fat in children with overweight

Simple item page
dc.contributor.authorLabayen Goñi, Idoia
dc.contributor.authorMedrano Echeverría, María
dc.contributor.authorArenaza Etxeberría, Lide
dc.contributor.authorMaiz, Edurne
dc.contributor.authorOsés Recalde, Maddi
dc.contributor.authorMartínez Vizcaíno, Vicente
dc.contributor.authorRuiz, Jonatan R.
dc.contributor.authorOrtega, Francisco B.
dc.contributor.departmentInstitute on Innovation and Sustainable Development in Food Chain - ISFOODen
dc.date.accessioned2020-05-29T07:13:45Z
dc.date.available2020-05-29T07:13:45Z
dc.date.issued2020
dc.description.abstractOBJECTIVE Pediatric hepatic steatosis is highly prevalent and closely related to type 2 diabetes. This study aimed to determine whether the addition of supervised exercise to a family-based lifestyle and psycho-educational intervention results in greater reduction of percentage of hepatic fat (HF), adiposity, and cardiometabolic risk factors in children with overweight/obesity. RESEARCH DESIGN AND METHODS The study subjects of this nonrandomized, two-arm, parallel design clinical trial were 116 overweight/obese children (10.6 +/- 1.1 years of age, 53.4% girls) living in Vitoria-Gasteiz (Spain). For 22 weeks, they followed either a lifestyle and psycho-education program (control intervention [CInt], N = 57), consisting of two family-based education sessions/month, or the same plus supervised exercise (intensive intervention [II], N = 59) focused mainly on high-intensity aerobic workouts (3 sessions/week, 90 min/session). The primary outcome was the change in percentage of HF (as measured by MRI) between baseline and the end of the intervention period. Secondary outcomes included changes in BMI, fat mass index (FMI), abdominal fat (measured by DEXA), blood pressure, triglycerides, HDL, LDL, gamma-glutamyl transferase, glucose, and insulin concentrations. RESULTS A total of 102 children completed the trial (N = 53 and N = 49 in the CInt and II groups, respectively). Percentage of HF decreased only in the II group (-1.20 +/- 0.31% vs. 0.04 +/- 0.30%, II and CInt groups, respectively), regardless of baseline value and any change in adiposity (P < 0.01). BMI, FMI, abdominal fat (P <= 0.001), and insulin (P < 0.05) were reduced in both groups. CONCLUSIONS Multicomponent intervention programs that include exercise training may help to reduce adiposity, insulin resistance, and hepatic steatosis in overweight/obese children.en
dc.description.sponsorshipThis project was funded by the Spanish Ministry of Health 'Fondos de Investigation Sanitaria del Institute de Salud Carlos III' (PI13/01335), the Spanish Ministry of Industry and Competitiveness (DEP2016-78377-R), and by EU Fondos Estructurales de la Unión Europea (FEDER) funds ('Una manera de hacer Europa'). Support was also provided by grants from the Spanish Ministry of Education, Culture and Sports (FPU14/03329), the Education Department of the Government of the Basque Country (PRE_2016_1_0057, PRE_2017_2_0224, PRE_2018_2_0057), the University of Granada Plan Propio de Investigacion 2016-Excellence actions: Unit of Excellence on Exercise and Health (UCEES), and Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades (FEDER, ref. SOMM17/6107/UGR).en
dc.format.extent32 p.
dc.format.mimetypeapplication/pdfen
dc.format.mimetypeapplication/zipen
dc.identifier.doi10.2337/dc19-0351
dc.identifier.issn0149-5992
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/37005
dc.language.isoengen
dc.publisherAmerican Diabetes Associationen
dc.relation.ispartofDiabetes Care, 2020, 43 (2), 306-313en
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/1PE/DEP2016-78377-Ren
dc.relation.publisherversionhttps://doi.org/10.2337/dc19-0351
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.subjectHepatic steatosisen
dc.subjectChildhooden
dc.subjectPhysical activityen
dc.subjectNutritionen
dc.subjectPsychologyen
dc.subjectObesityen
dc.titleEffects of exercise in addition to a family-based lifestyle intervention program on hepatic fat in children with overweighten
dc.typeinfo:eu-repo/semantics/articleen
dc.typeArtículo / Artikuluaes
dc.type.versioninfo:eu-repo/semantics/acceptedVersionen
dc.type.versionVersión aceptada / Onetsi den bertsioaes
dspace.entity.typePublication
relation.isAuthorOfPublicationb36e2b1d-3088-4089-806e-fd3040e9583a
relation.isAuthorOfPublication304856ca-cc85-4094-8ca3-b17f4c5f33de
relation.isAuthorOfPublication40824565-b282-4525-900f-f590b8aeb642
relation.isAuthorOfPublicationa3f4aa23-172a-47fb-9faf-647f655f7085
relation.isAuthorOfPublication.latestForDiscoveryb36e2b1d-3088-4089-806e-fd3040e9583a

Files

Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
2020020547_Labayen_EffectsExercise.pdf
Size:
384.76 KB
Format:
Adobe Portable Document Format
Download
No Thumbnail Available
Name:
MatCompl.zip
Size:
677.36 KB
Format:
ZIP
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

Artículos de revista ISFOOD - ISFOOD aldizkari artikuluak
Artículos de revista - Aldizkari artikuluak