Centile reference curves of the ultrasound-based characteristics of the rectus femoris muscle composition in children at 4–11 years old

García Alonso, Yesenia; Alonso Martínez, Alicia; García Hermoso, Antonio; Legarra Gorgoñón, Gaizka; Izquierdo Redín, Mikel; Ramírez Vélez, Robinson

Centile reference curves of the ultrasound-based characteristics of the rectus femoris muscle composition in children at 4–11 years old

dc.contributor.author	García Alonso, Yesenia
dc.contributor.author	Alonso Martínez, Alicia
dc.contributor.author	García Hermoso, Antonio
dc.contributor.author	Legarra Gorgoñón, Gaizka
dc.contributor.author	Izquierdo Redín, Mikel
dc.contributor.author	Ramírez Vélez, Robinson
dc.contributor.department	Ciencias de la Salud	es_ES
dc.contributor.department	Osasun Zientziak	eu
dc.date.accessioned	2023-11-07T19:13:32Z
dc.date.available	2023-11-07T19:13:32Z
dc.date.issued	2023
dc.date.updated	2023-11-07T18:50:27Z
dc.description.abstract	Quantitative diagnostic ultrasound has been proposed as a way to characterize muscle structure, but there is a lack of normative data for children. This study aims to establish age-specific normal ranges for echo-intensity (EI), cross-sectional area (CSA), muscular thickness (MT), and subcutaneous adipose thickness (SAT) values of the rectus femoris muscle in typically developing children. The study recruited 497 children (288 boys and 209 girls) aged 4–10.9 years (mean age 7.39 years), and muscle parameters were measured using 2D B-mode ultrasound. Percentile values and reference curves were calculated using the Lambda, Mu, and Sigma method (LMS). The results showed small variation between measurements for boys compared to girls, with the most significant difference in EI, CSA, and MT values. EI decreased with age, with the most pronounced curve in boys. SAT increased in both sexes, with a slightly higher increase in girls after the age of 9.0 years. This study provides the first age-specific reference norms for the rectus femoris muscle architecture in children, and further research is needed to validate these curves and determine their clinical utility.	en
dc.description.sponsorship	This work was supported by the Department of Education of the Government of Navarra (Spain), Grant/Award Number: CENEDUCA1/2019; Instituto de Salud Carlos III. Acknowledgments	en
dc.format.mimetype	application/pdf	en
dc.format.mimetype	application/msword	en
dc.identifier.citation	García-Alonso, Y., Alonso-Martínez, A. M., García-Hermoso, A., Legarra-Gorgoñon, G., Izquierdo, M., Ramírez-Vélez, R. (2023) Centile reference curves of the ultrasound-based characteristics of the rectus femoris muscle composition in children at 4-11 years old. Frontiers in Pediatrics, 11, 1-9. https://doi.org/10.3389/fped.2023.1168253.	en
dc.identifier.doi	10.3389/fped.2023.1168253
dc.identifier.issn	2296-2360
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/46710
dc.language.iso	eng	en
dc.publisher	Frontiers Media	en
dc.relation.ispartof	Frontiers in Pediatrics 11, 2023	en
dc.relation.projectID	info:eu-repo/grantAgreement/Gobierno de Navarra///
dc.relation.publisherversion	https://doi.org/10.3389/fped.2023.1168253
dc.rights	© 2023 García-Alonso, Alonso-Martínez, García-Hermoso, Legarra-Gorgoñon, Izquierdo and Ramírez-Vélez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.subject	Histogram	en
dc.subject	Percentile	en
dc.subject	Reference values	en
dc.subject	Subcutaneous fat	en
dc.subject	Ultrasound	en
dc.title	Centile reference curves of the ultrasound-based characteristics of the rectus femoris muscle composition in children at 4–11 years old	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion
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