Heart rate and its variability are associated with resting metabolic rate and substrate oxidation in young women but not in men

Alcántara Alcántara, Juan Manuel; González-Acedo, Anabel; Amaro Gahete, Francisco J.; Plaza Florido, Abel

Heart rate and its variability are associated with resting metabolic rate and substrate oxidation in young women but not in men

dc.contributor.author	Alcántara Alcántara, Juan Manuel
dc.contributor.author	González-Acedo, Anabel
dc.contributor.author	Amaro Gahete, Francisco J.
dc.contributor.author	Plaza Florido, Abel
dc.date.accessioned	2024-11-22T11:19:59Z
dc.date.available	2024-11-22T11:19:59Z
dc.date.issued	2024-09-20
dc.date.updated	2024-11-22T11:07:56Z
dc.description.abstract	Background: This study aims to examine the relationship between resting vagal-related heart rate variability (HRV) parameters and heart rate (HR) with resting metabolic rate (RMR) and respiratory exchange ratio (RER) in young adults. Methods: A total of 74 young adults (22 ± 2 years old, 51 women) were included in this cross-sectional study. HRV was assessed using a HR monitor, whereas RMR and RER were determined by indirect calorimetry. Results: Linear regression analyses showed a positive association between HR and RER in women (standardized β = 0.384, p = 0.008), while negative associations were observed between vagal-related HRV parameters and RER in women (β ranged from -0.262 to ¿0.254, all p≤ 0.042). No significant association was found between the abovementioned physiological parameters in men. Conclusion: Here, we show that HR is positively associated with RER in young women but not in men, while vagal-related HRV parameters are inversely related to RMR, therefore suggesting a potential sexual dimorphism between cardiac rhythm and its relationship with markers of cardiometabolic health status. Trial Registration: ClinicalTrials.gov identifier: NCT02365129.	en
dc.description.sponsorship	The study was supported by the Junta de Andalucía, Consejería de Transformación Económica, Industria, Conocimiento y Universidades (P18-RT-4455), Dirección General de Investigación y Transferencia del Conocimiento and European Regional Development Funds (ERDF) (SOMM17/6107/UGR), the Spanish Ministry of Economy and Competitiveness via Retos de la Sociedad (DEP2016-79512-R), the Spanish Ministry of Education (FPU 15/04059 [to J.M.A.A.]), the University of Granada Plan Propio de Investigación 2016¿Excellence Actions: Unit of Excellence on Exercise and Health (UCEES), the University of Granada Plan Propio 2020 Programa Contratos-Puente (to J.M.A.A.), the Juan de la Cierva Formación postdoctoral grant (FJC2020-044453-I) funded by MCIN/AEI/10.13039/501100011033 and by ¿European Union NextGenerationEU/PRTR¿ (to J.M.A.A.). Finally, is supported in part by PERC Systems Biology Fund (to A.P.-F.).
dc.format.mimetype	application/pdf	en
dc.format.mimetype	application/msword	en
dc.identifier.citation	Alcantara, J., González-Acedo, A., Amaro-Gahete, F., Plaza-Florido, A. (2024). Heart rate and its variability are associated with resting metabolic rate and substrate oxidation in young women but not in men. American Journal of Human Biology, 28(9), 929-936. https://doi.org/10.1002/ajhb.24157.
dc.identifier.doi	10.1002/ajhb.24157
dc.identifier.issn	1042-0533
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/52570
dc.language.iso	eng
dc.publisher	Wiley
dc.relation.ispartof	American Journal of Human Biology (2024), vol. 36, núm. 11, e24157
dc.relation.projectID	info:eu-repo/grantAgreement/AEI//DEP2016-79512-R/ES/
dc.relation.projectID	info:eu-repo/grantAgreement/MECD//FPU15%2F04059/ES/
dc.relation.projectID	info:eu-repo/grantAgreement/AEI//FJC2020-044453-I/
dc.relation.publisherversion	https://doi.org/10.1002/ajhb.24157
dc.rights	© 2024 The Author(s). This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/
dc.subject	Gas exchange	en
dc.subject	Kubios	en
dc.subject	Parasympathetic	en
dc.subject	Substrate oxidation	en
dc.subject	Vagal nerve	en
dc.title	Heart rate and its variability are associated with resting metabolic rate and substrate oxidation in young women but not in men	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion
dspace.entity.type	Publication
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