Accelerated forgetting in temporal lobe epilepsy: When does it occur?

Contador Castillo, Israel; Sánchez, Abraham; Kopelman, Michael D.; González de la Aleja, Jesús; Ruisoto, Pablo

Publication:
Accelerated forgetting in temporal lobe epilepsy: When does it occur?

dc.contributor.author	Contador Castillo, Israel	es_ES
dc.contributor.author	Sánchez, Abraham	es_ES
dc.contributor.author	Kopelman, Michael D.	es_ES
dc.contributor.author	González de la Aleja, Jesús	es_ES
dc.contributor.author	Ruisoto, Pablo
dc.contributor.department	Ciencias de la Salud	es_ES
dc.contributor.department	Osasun Zientziak	eu
dc.date.accessioned	2022-02-04T12:24:59Z
dc.date.available	2022-05-05T23:00:10Z
dc.date.issued	2021
dc.description.abstract	Objective: the main goal of the study was to analyse differences in the forgetting rates of Temporal Lobe Epilepsy (TLE) patients at different intervals (30 sec, 10 min, 1 day and 1 week) compared with those of healthy controls. A secondary aim of this research was to provide an assessment of the relationship between clinical epilepsy-related variables and forgetting rates in TLE patients. Method: the sample was composed of 14 TLE patients and 14 healthy matched controls. All participants underwent a full standardised neuropsychological assessment including general intelligence, executive functioning, memory, language and other variables, such as depression, anxiety or everyday memory failures. Two specific memory tasks, consisting of cued recall of 4 short stories and 4 routes, were carried out at four different intervals. Results: there was a significant difference between groups at 10-min interval on the stories task, with the TLE group displaying greater forgetting than healthy controls. None of the other intervals on either task showed significant group differences. No differences were found when controlling for clinical epilepsy-related variables. Conclusion: forgetting of verbal information at 10 min was greater in patients with TLE compared with controls, but accelerated longer term forgetting was not found. This study suggests that a late consolidation process is not necessarily impaired in TLE patients.	en
dc.description.sponsorship	Israel Contador was supported by a post-doc fellowship (JC 2011-0012) from the Spanish Ministry of Education.	en
dc.embargo.lift	2022-05-05
dc.embargo.terms	2022-05-05
dc.format.extent	43 p.
dc.format.mimetype	application/pdf	en
dc.format.mimetype	application/msword	en
dc.identifier.doi	10.1016/j.cortex.2021.03.035
dc.identifier.issn	0010-9452
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/42110
dc.language.iso	eng	en
dc.publisher	Elsevier
dc.relation.ispartof	Cortex, Vol. 141, August 2021, Pages 190-200
dc.relation.publisherversion	https://doi.org/10.1016/j.cortex.2021.03.035
dc.rights	© 2021 Elsevier Ltd. Published by Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess	en
dc.rights.accessRights	Acceso abierto / Sarbide irekia	es
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject	Accelerated long-term forgetting	en
dc.subject	Forgetting	en
dc.subject	Memory consolidation	en
dc.subject	Temporal lobe epilepsy	en
dc.title	Accelerated forgetting in temporal lobe epilepsy: When does it occur?	en
dc.type	info:eu-repo/semantics/article	en
dc.type	Artículo / Artikulua	es
dc.type.version	info:eu-repo/semantics/acceptedVersion	en
dc.type.version	Versión aceptada / Onetsi den bertsioa	es
dspace.entity.type	Publication
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relation.isAuthorOfPublication.latestForDiscovery	67d90c33-1a8d-4a17-b259-940ae5d3674a