Prevalence and risk factors for wheezing in infants in the region of Pamplona, Spain

dc.contributor.authorÁlvarez Álvarez, Ismael
dc.contributor.authorNiu, Hao
dc.contributor.authorAguinaga Ontoso, Inés
dc.contributor.authorGuillén Grima, Francisco
dc.contributor.departmentCiencias de la Saludes_ES
dc.contributor.departmentOsasun Zientziakeu
dc.contributor.funderGobierno de Navarra / Nafarroako Gobernua: 6106es
dc.date.accessioned2017-09-09T11:52:19Z
dc.date.issued2016
dc.description.abstractBackground: Wheezing in the first year of life affects life’s quality of the baby and the family. Risk factors such as male gender, nursery attending or a family history of asthma, and protective factors such as breastfeeding more than 6 months have been previously described. The aim of this study is to study the prevalence and risk factors for wheezing ever and recurrent wheezing in the first year of life in infants in the region of Pamplona, Spain. Material and methods: This cross-sectional study was part of the International Study of Wheezing in Infants (Estudio Internacional de Sibilancias en Lactantes, EISL). Between 2006 and 2008, participating families answered a standardized validated questionnaire on respiratory symptoms, environmental factors or family issues. An analysis with the chi square test (statistical significance p<0.05) identified the risk factors for wheezing ever and recurrent wheezing, which were assessed using logistic regression. Results: 1065 questionnaires were answered. The prevalence of wheezing ever and recurrent wheezing were 31.2% and 12.3%, respectively. Male gender (p=<0.001), a history of pneumonia (p=<0.001) or nursery attendance (p=<0.001) were some of the risk factors found for wheezing ever. Infant eczema (p=<0.001), nursery attendance (p=<0.001) or prematurity (p=<0.001) were risk factors for recurrent wheezing. No associations with duration of breastfeeding (p=0.116 and p=0.851) or mould stains at home (p=0.153 and p=0.992) were found. Conclusion: The study of prevalence and risk factors for wheezing shows the importance of this public health problem, and allows the development of control and treatment strategies against preventable factors.en
dc.description.sponsorshipThis study has been funded by two Research Grants from Carlos III Institute, Spanish Ministry of Health and Consumer Affairs Ref, PI 050918, and from the Department of Health, Government of Navarra, Spain, Ref 6106.en
dc.format.mimetypeapplication/pdfen
dc.identifier.doi10.1016/j.aller.2015.08.002
dc.identifier.issn0301-0546 (Print)
dc.identifier.issn1578-1267 (Electronic)
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/25555
dc.language.isoengen
dc.publisherElsevieren
dc.publisherSociedad Española de Inmunología Clínica y Alergología Pediátrica (SEICAP)es_ES
dc.relation.ispartofAllergologia et Immunopathologia, Volume 44, Issue 5, September–October 2016, Pages 415-421en
dc.relation.publisherversionhttps://doi.org/10.1016/j.aller.2015.08.002
dc.rights© 2015 SEICAP. Published by Elsevier España, S.L.U. The manuscript version is made available under the CC BY-NC-ND 4.0 license.en
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAsthmaen
dc.subjectEpidemiologyen
dc.subjectInfanten
dc.subjectPrevalenceen
dc.subjectRisk factorsen
dc.subjectWheezingen
dc.titlePrevalence and risk factors for wheezing in infants in the region of Pamplona, Spainen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePublication
relation.isAuthorOfPublication8a049a5c-d203-4214-b6c0-1587949ae327
relation.isAuthorOfPublicatione7178013-f5e6-4100-80b2-23f1d6cb6408
relation.isAuthorOfPublicationdfbf180f-dd66-42b9-ba45-2de0b3a334d5
relation.isAuthorOfPublication.latestForDiscoverye7178013-f5e6-4100-80b2-23f1d6cb6408

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