Synergic removal of Aflatoxin B1 in oily matrices by focusing on the peroxidase-like nanozymes-driven strategies: mechanisms and intermediate toxicity, nutritional impact, advances and challenges

Date

2025-09-01

Authors

Faraji, Ali Reza
Farahanipour, Alireza
Tehrani, Elnaz
Khoramdareh, Niloufar Bakhshi
Dashtabadi, E.
Jafari, Seyede Zeynab
Shojaei, Najmeh
Hekmatian, Zahra
Saeedi, S.

Director

Publisher

Elsevier
Acceso abierto / Sarbide irekia
Artículo / Artikulua
Versión publicada / Argitaratu den bertsioa

Project identifier

Impacto
Google Scholar
No disponible en Scopus

Abstract

Background: oilseeds and extracted oils, as the supplier of at least 40 % of calories, dietary essential fatty acids, and food flavor, due to insufficient cultivation-harvesting techniques, processing and long-term storage in improper conditions, and lack of adequate food-safety standards and/or official consideration, are prone to contamination by AFB1. Given its irreversible adverse effects on consumer health and food/feed safety due to various factors (e.g., high chemical stability of lipophilic AFB1, transformation to other toxic derivatives, and chemical interaction with oily matrices), developing a decontamination approach from a safety/efficiency perspective is imperative. Scope and approach: this review provides the recent progress on the AFB1 detoxification from oily matrices by focusing on the peroxidase-based nanozymes technologies and enzymatic-like mechanisms of reactive species in detail for the first time. Significantly, the superiority of enzymatic-like activity in capturing/detoxifying AFB1 from oily matrices, change in nutritional quality, organoleptic profiles, and physicochemical properties of oils, and mechanism of action are highlighted by a comparison with various edible oil remediation systems (i.e., physicochemical, physical, chemical, and biological). Key findings and conclusions: The peroxidase nanozyme-based technologies could be of primary importance in the remediation of AFB1 from oily matrices due to the unique merits of nanozymes (e.g., low-cost, size/surface-dependent properties, excellent efficiency and durability/stability, recoverability, biocompatibility, many capabilities to maintain the nutritional quality, and without require to any pre-treatment). Finally, this review aimed to provide several beneficial insights regarding safety, universality, finance, ecology, rapidity, selectivity, detoxification path, and toxicity/biological nature of transformed products in peroxidase-mimicking nanozyme technologies.

Description

Keywords

Aflatoxin B1, Nanozyme, Peroxidase-like, Enzyme-mimetic degradation, Edible oil, Detoxification

Department

Ciencias / Zientziak / Institute for Advanced Materials and Mathematics - INAMAT2

Faculty/School

Degree

Doctorate program

item.page.cita

Faraji, A. R., Gil, A., Farahanipour, A., Tehrani, E., Khoramdareh, N. B., Dashtabadi, E., Jafari, S., Shojaei, N., Hekmatian, Z., Saeedi, S. (2025). Synergic removal of Aflatoxin B1 in oily matrices by focusing on the peroxidase-like nanozymes-driven strategies: mechanisms and intermediate toxicity, nutritional impact, advances and challenges. Trends in Food Science & Technology, 163, 1-22. https://doi.org/10.1016/j.tifs.2025.105135.

item.page.rights

© 2025 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.

Licencia

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